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Comparative study of the effect of 50% pyruvic and 30% salicylic peels on the skin lipid film in patients with acne vulgaris.
J Cosmet Dermatol. 2014 Mar; 13(1):15-21.JC

Abstract

Pyruvic (alfa-keto acid) and salicylic (beta-hydroxy acid) acids are superficial peels frequently used in patients with acne vulgaris.

AIM

The aim of the study was to compare the effect of 50% pyruvic and 30% salicylic peels on facial sebum secretion in patients with acne vulgaris, aged 13-30.

MATERIAL AND METHODS

The level of secreted sebum was determined in 20 men and women. Ten patients were treated with 50% pyruvic acid and the remaining 10 with 30% salicylic acid. Each peel was applied five times at 2-week intervals. The sebum measurements were taken in the T- and U-zones using a Sebumeter SM 815 (Courage & Khazaka, Germany). The last, sixth measurement was taken 2 weeks after the treatment.

RESULTS

A statistically significant decrease in the level of secreted sebum in both U- and T- zones was observed in the patients studied after the third application of 50% pyruvic peel and the second application of 30% salicylic peel. Two weeks following the completion of therapy, sebumetric measurements demonstrated a greater reduction in the facial skin lipid film among the patients treated with salicylic peel.

CONCLUSIONS

Peels with 50% pyruvic acid and 30% salicylic acid are the procedures that significantly contributed to a decrease in the level of secreted sebum on the facial skin surface in the group of patients studied. A greater therapeutic effect was observed following 30% salicylic peel, which might be associated with its high lipophilic properties and easier penetration through the lipid barriers of the epidermis.

Authors+Show Affiliations

Department of Cosmetology, Medical University of Lodz, Lodz, Poland.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24641601

Citation

Marczyk, Beata, et al. "Comparative Study of the Effect of 50% Pyruvic and 30% Salicylic Peels On the Skin Lipid Film in Patients With Acne Vulgaris." Journal of Cosmetic Dermatology, vol. 13, no. 1, 2014, pp. 15-21.
Marczyk B, Mucha P, Budzisz E, et al. Comparative study of the effect of 50% pyruvic and 30% salicylic peels on the skin lipid film in patients with acne vulgaris. J Cosmet Dermatol. 2014;13(1):15-21.
Marczyk, B., Mucha, P., Budzisz, E., & Rotsztejn, H. (2014). Comparative study of the effect of 50% pyruvic and 30% salicylic peels on the skin lipid film in patients with acne vulgaris. Journal of Cosmetic Dermatology, 13(1), 15-21. https://doi.org/10.1111/jocd.12050
Marczyk B, et al. Comparative Study of the Effect of 50% Pyruvic and 30% Salicylic Peels On the Skin Lipid Film in Patients With Acne Vulgaris. J Cosmet Dermatol. 2014;13(1):15-21. PubMed PMID: 24641601.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparative study of the effect of 50% pyruvic and 30% salicylic peels on the skin lipid film in patients with acne vulgaris. AU - Marczyk,Beata, AU - Mucha,Paulina, AU - Budzisz,Elżbieta, AU - Rotsztejn,Helena, PY - 2013/04/05/accepted PY - 2014/3/20/entrez PY - 2014/3/20/pubmed PY - 2014/12/15/medline KW - acne vulgaris KW - pyruvic peel KW - salicylic peel KW - sebumeter SP - 15 EP - 21 JF - Journal of cosmetic dermatology JO - J Cosmet Dermatol VL - 13 IS - 1 N2 - UNLABELLED: Pyruvic (alfa-keto acid) and salicylic (beta-hydroxy acid) acids are superficial peels frequently used in patients with acne vulgaris. AIM: The aim of the study was to compare the effect of 50% pyruvic and 30% salicylic peels on facial sebum secretion in patients with acne vulgaris, aged 13-30. MATERIAL AND METHODS: The level of secreted sebum was determined in 20 men and women. Ten patients were treated with 50% pyruvic acid and the remaining 10 with 30% salicylic acid. Each peel was applied five times at 2-week intervals. The sebum measurements were taken in the T- and U-zones using a Sebumeter SM 815 (Courage & Khazaka, Germany). The last, sixth measurement was taken 2 weeks after the treatment. RESULTS: A statistically significant decrease in the level of secreted sebum in both U- and T- zones was observed in the patients studied after the third application of 50% pyruvic peel and the second application of 30% salicylic peel. Two weeks following the completion of therapy, sebumetric measurements demonstrated a greater reduction in the facial skin lipid film among the patients treated with salicylic peel. CONCLUSIONS: Peels with 50% pyruvic acid and 30% salicylic acid are the procedures that significantly contributed to a decrease in the level of secreted sebum on the facial skin surface in the group of patients studied. A greater therapeutic effect was observed following 30% salicylic peel, which might be associated with its high lipophilic properties and easier penetration through the lipid barriers of the epidermis. SN - 1473-2165 UR - https://www.unboundmedicine.com/medline/citation/24641601/Comparative_study_of_the_effect_of_50_pyruvic_and_30_salicylic_peels_on_the_skin_lipid_film_in_patients_with_acne_vulgaris_ L2 - https://doi.org/10.1111/jocd.12050 DB - PRIME DP - Unbound Medicine ER -