Tags

Type your tag names separated by a space and hit enter

Iatrogenic occlusion of the ophthalmic artery after cosmetic facial filler injections: a national survey by the Korean Retina Society.

Abstract

IMPORTANCE

Iatrogenic occlusion of the ophthalmic artery and its branches is a rare but devastating complication of cosmetic facial filler injections.

OBJECTIVE

To investigate clinical and angiographic features of iatrogenic occlusion of the ophthalmic artery and its branches caused by cosmetic facial filler injections.

DESIGN, SETTING, AND PARTICIPANTS

Data from 44 patients with occlusion of the ophthalmic artery and its branches after cosmetic facial filler injections were obtained retrospectively from a national survey completed by members of the Korean Retina Society from 27 retinal centers. Clinical features were compared between patients grouped by angiographic findings and injected filler material.

MAIN OUTCOMES AND MEASURES

Visual prognosis and its relationship to angiographic findings and injected filler material.

RESULTS

Ophthalmic artery occlusion was classified into 6 types according to angiographic findings. Twenty-eight patients had diffuse retinal and choroidal artery occlusions (ophthalmic artery occlusion, generalized posterior ciliary artery occlusion, and central retinal artery occlusion). Sixteen patients had localized occlusions (localized posterior ciliary artery occlusion, branch retinal artery occlusion, and posterior ischemic optic neuropathy). Patients with diffuse occlusions showed worse initial and final visual acuity and less visual gain compared with those having localized occlusions. Patients receiving autologous fat injections (n = 22) had diffuse ophthalmic artery occlusions, worse visual prognosis, and a higher incidence of combined brain infarction compared with patients having hyaluronic acid injections (n = 13).

CONCLUSIONS AND RELEVANCE

Clinical features of iatrogenic occlusion of the ophthalmic artery and its branches following cosmetic facial filler injections were diverse according to the location and extent of obstruction and the injected filler material. Autologous fat injections were associated with a worse visual prognosis and a higher incidence of combined cerebral infarction. Extreme caution and care should be taken during these injections, and physicians should be aware of a diverse spectrum of complications following cosmetic facial filler injections.

Links

  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Gyeonggi, Korea.

    ,

    Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Gyeonggi, Korea.

    ,

    Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Gyeonggi, Korea.

    ,

    Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

    ,

    Department of Ophthalmology, College of Medicine, Seoul St Mary's Hospital, The Catholic University of Korea, Seoul, Korea.

    ,

    Department of Ophthalmology, Soonchunhyang University Hospital, Seoul, Korea.

    ,

    Department of Ophthalmology, Kyung Hee University Medical Center, College of Medicine, Kyung Hee University, Seoul, Korea.

    ,

    Department of Ophthalmology, Inje University College of Medicine, Busan Paik Hospital, Busan, Korea.

    ,

    Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea.

    ,

    Department of Ophthalmology, Kim's Eye Hospital, Konyang University College of Medicine, Seoul, Korea.

    Source

    JAMA ophthalmology 132:6 2014 Jun pg 714-23

    MeSH

    Adipose Tissue
    Adult
    Arterial Occlusive Diseases
    Cosmetic Techniques
    Cross-Sectional Studies
    Face
    Female
    Fluorescein Angiography
    Humans
    Hyaluronic Acid
    Iatrogenic Disease
    Incidence
    Injections, Intradermal
    Male
    Middle Aged
    Ophthalmic Artery
    Prognosis
    Radiography
    Republic of Korea
    Retinal Artery Occlusion
    Retrospective Studies
    Risk Assessment
    Societies, Medical
    Transplantation, Autologous
    Young Adult

    Pub Type(s)

    Comparative Study
    Journal Article
    Multicenter Study
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    24676334

    Citation

    Park, Kyu Hyung, et al. "Iatrogenic Occlusion of the Ophthalmic Artery After Cosmetic Facial Filler Injections: a National Survey By the Korean Retina Society." JAMA Ophthalmology, vol. 132, no. 6, 2014, pp. 714-23.
    Park KH, Kim YK, Woo SJ, et al. Iatrogenic occlusion of the ophthalmic artery after cosmetic facial filler injections: a national survey by the Korean Retina Society. JAMA Ophthalmol. 2014;132(6):714-23.
    Park, K. H., Kim, Y. K., Woo, S. J., Kang, S. W., Lee, W. K., Choi, K. S., ... Kim, J. W. (2014). Iatrogenic occlusion of the ophthalmic artery after cosmetic facial filler injections: a national survey by the Korean Retina Society. JAMA Ophthalmology, 132(6), pp. 714-23. doi:10.1001/jamaophthalmol.2013.8204.
    Park KH, et al. Iatrogenic Occlusion of the Ophthalmic Artery After Cosmetic Facial Filler Injections: a National Survey By the Korean Retina Society. JAMA Ophthalmol. 2014;132(6):714-23. PubMed PMID: 24676334.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Iatrogenic occlusion of the ophthalmic artery after cosmetic facial filler injections: a national survey by the Korean Retina Society. AU - Park,Kyu Hyung, AU - Kim,Yong-Kyu, AU - Woo,Se Joon, AU - Kang,Se Woong, AU - Lee,Won Ki, AU - Choi,Kyung Seek, AU - Kwak,Hyung Woo, AU - Yoon,Ill Han, AU - Huh,Kuhl, AU - Kim,Jong Woo, AU - ,, PY - 2014/3/29/entrez PY - 2014/3/29/pubmed PY - 2014/8/19/medline SP - 714 EP - 23 JF - JAMA ophthalmology JO - JAMA Ophthalmol VL - 132 IS - 6 N2 - IMPORTANCE: Iatrogenic occlusion of the ophthalmic artery and its branches is a rare but devastating complication of cosmetic facial filler injections. OBJECTIVE: To investigate clinical and angiographic features of iatrogenic occlusion of the ophthalmic artery and its branches caused by cosmetic facial filler injections. DESIGN, SETTING, AND PARTICIPANTS: Data from 44 patients with occlusion of the ophthalmic artery and its branches after cosmetic facial filler injections were obtained retrospectively from a national survey completed by members of the Korean Retina Society from 27 retinal centers. Clinical features were compared between patients grouped by angiographic findings and injected filler material. MAIN OUTCOMES AND MEASURES: Visual prognosis and its relationship to angiographic findings and injected filler material. RESULTS: Ophthalmic artery occlusion was classified into 6 types according to angiographic findings. Twenty-eight patients had diffuse retinal and choroidal artery occlusions (ophthalmic artery occlusion, generalized posterior ciliary artery occlusion, and central retinal artery occlusion). Sixteen patients had localized occlusions (localized posterior ciliary artery occlusion, branch retinal artery occlusion, and posterior ischemic optic neuropathy). Patients with diffuse occlusions showed worse initial and final visual acuity and less visual gain compared with those having localized occlusions. Patients receiving autologous fat injections (n = 22) had diffuse ophthalmic artery occlusions, worse visual prognosis, and a higher incidence of combined brain infarction compared with patients having hyaluronic acid injections (n = 13). CONCLUSIONS AND RELEVANCE: Clinical features of iatrogenic occlusion of the ophthalmic artery and its branches following cosmetic facial filler injections were diverse according to the location and extent of obstruction and the injected filler material. Autologous fat injections were associated with a worse visual prognosis and a higher incidence of combined cerebral infarction. Extreme caution and care should be taken during these injections, and physicians should be aware of a diverse spectrum of complications following cosmetic facial filler injections. SN - 2168-6173 UR - https://www.unboundmedicine.com/medline/citation/24676334/Iatrogenic_occlusion_of_the_ophthalmic_artery_after_cosmetic_facial_filler_injections:_a_national_survey_by_the_Korean_Retina_Society_ L2 - https://jamanetwork.com/journals/jamaophthalmology/fullarticle/10.1001/jamaophthalmol.2013.8204 DB - PRIME DP - Unbound Medicine ER -