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A comparison of the sensitivity of four Staphylococcus aureus isolates to two chlorine-based disinfectants and an eco-friendly commercially available cleaning agent.
Int J Environ Health Res. 2015; 25(2):115-25.IJ

Abstract

The aim of this study was to determine the effect of household bleach, a sodium dichloroisocyanurate (NaDCC)-based disinfectant and an eco-friendly cleaning agent (EFCA) on four Staphylococcus aureus strains, including two isolated from community infections. The products were assessed using the suspension (EN 1276) and surface (EN 13697) tests, while biofilm activity was determined using the 96-well plate method. Bleach and NaDCC caused > 5 log reduction in viable counts within 5 min in suspension, whilst on surfaces the reduction was < 3 log. Bleach at 5000 ppm free available chlorine completely eradicated MSSA NCTC 13297 and PVL CA MSSA biofilms within 10 min, but not at 500 and 50 ppm, NaDCC was less effective against biofilms. The EFCA demonstrated no antimicrobial activity. It is of concern that at the recommended "use" dilution, bleach did not eradicate biofilms. Although increasing contact time and/or concentration should improve the activity, this may not be acceptable to the user.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Adukwu EC
a Department of Biology and Biomedical Science , University of the West of England , Bristol , UK.
Allen SC
No affiliation info available
Phillips CA
No affiliation info available

MeSH

BiofilmsCitratesCyclohexenesDisinfectantsEthanolLactic AcidLimoneneMicrobial Sensitivity TestsSodium CitrateSodium HypochloriteStaphylococcus aureusTerpenesTriazines

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24725246

Citation

Adukwu, Emmanuel C., et al. "A Comparison of the Sensitivity of Four Staphylococcus Aureus Isolates to Two Chlorine-based Disinfectants and an Eco-friendly Commercially Available Cleaning Agent." International Journal of Environmental Health Research, vol. 25, no. 2, 2015, pp. 115-25.
Adukwu EC, Allen SC, Phillips CA. A comparison of the sensitivity of four Staphylococcus aureus isolates to two chlorine-based disinfectants and an eco-friendly commercially available cleaning agent. Int J Environ Health Res. 2015;25(2):115-25.
Adukwu, E. C., Allen, S. C., & Phillips, C. A. (2015). A comparison of the sensitivity of four Staphylococcus aureus isolates to two chlorine-based disinfectants and an eco-friendly commercially available cleaning agent. International Journal of Environmental Health Research, 25(2), 115-25. https://doi.org/10.1080/09603123.2014.903905
Adukwu EC, Allen SC, Phillips CA. A Comparison of the Sensitivity of Four Staphylococcus Aureus Isolates to Two Chlorine-based Disinfectants and an Eco-friendly Commercially Available Cleaning Agent. Int J Environ Health Res. 2015;25(2):115-25. PubMed PMID: 24725246.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A comparison of the sensitivity of four Staphylococcus aureus isolates to two chlorine-based disinfectants and an eco-friendly commercially available cleaning agent. AU - Adukwu,Emmanuel C, AU - Allen,Stuart C, AU - Phillips,Carol Ann, Y1 - 2014/04/14/ PY - 2014/4/15/entrez PY - 2014/4/15/pubmed PY - 2015/11/17/medline KW - biofilm KW - disinfection KW - staphylococcus SP - 115 EP - 25 JF - International journal of environmental health research JO - Int J Environ Health Res VL - 25 IS - 2 N2 - The aim of this study was to determine the effect of household bleach, a sodium dichloroisocyanurate (NaDCC)-based disinfectant and an eco-friendly cleaning agent (EFCA) on four Staphylococcus aureus strains, including two isolated from community infections. The products were assessed using the suspension (EN 1276) and surface (EN 13697) tests, while biofilm activity was determined using the 96-well plate method. Bleach and NaDCC caused > 5 log reduction in viable counts within 5 min in suspension, whilst on surfaces the reduction was < 3 log. Bleach at 5000 ppm free available chlorine completely eradicated MSSA NCTC 13297 and PVL CA MSSA biofilms within 10 min, but not at 500 and 50 ppm, NaDCC was less effective against biofilms. The EFCA demonstrated no antimicrobial activity. It is of concern that at the recommended "use" dilution, bleach did not eradicate biofilms. Although increasing contact time and/or concentration should improve the activity, this may not be acceptable to the user. SN - 1369-1619 UR - https://www.unboundmedicine.com/medline/citation/24725246/A_comparison_of_the_sensitivity_of_four_Staphylococcus_aureus_isolates_to_two_chlorine_based_disinfectants_and_an_eco_friendly_commercially_available_cleaning_agent_ DB - PRIME DP - Unbound Medicine ER -