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Trends in prevalence and control of diabetes in the United States, 1988-1994 and 1999-2010.
Ann Intern Med. 2014 Apr 15; 160(8):517-25.AIM

Abstract

BACKGROUND

Trends in the prevalence and control of diabetes defined by hemoglobin A1c (HbA1c) levels are important for health care policy and planning.

OBJECTIVE

To update trends in the prevalence of diabetes, prediabetes, and glycemic control.

DESIGN

Cross-sectional.

SETTING

NHANES (National Health and Nutrition Examination Survey) in 1988-1994 and 1999-2010.

PARTICIPANTS

Adults aged 20 years or older.

MEASUREMENTS

We used calibrated HbA1c levels to define undiagnosed diabetes (≥6.5%); prediabetes (5.7% to 6.4%); and, among persons with diagnosed diabetes, glycemic control (<7.0% or <8.0%). Trends in HbA1c categories were compared with fasting glucose levels (≥7.0 mmol/L [≥126 mg/dL] and 5.6 to 6.9 mmol/L [100 to 125 mg/dL]).

RESULTS

In 2010, approximately 21 million U.S. adults aged 20 years or older had total confirmed diabetes (self-reported diabetes or diagnostic levels for both fasting glucose and calibrated HbA1c). During 2 decades, the prevalence of total confirmed diabetes increased, but the prevalence of undiagnosed diabetes remained fairly stable, reducing the proportion of total diabetes cases that are undiagnosed to 11% in 2005-2010. The prevalence of prediabetes was lower when defined by calibrated HbA1c levels than when defined by fasting glucose levels but has increased from 5.8% in 1988-1994 to 12.4% in 2005-2010 when defined by HbA1c levels. Glycemic control improved overall, but total diabetes prevalence was greater and diabetes was less controlled among non-Hispanic blacks and Mexican Americans compared with non-Hispanic whites.

LIMITATION

Cross-sectional design.

CONCLUSION

Over the past 2 decades, the prevalence of total diabetes has increased substantially. However, the proportion of undiagnosed diabetes cases decreased, suggesting improvements in screening and diagnosis. Among the growing number of persons with diagnosed diabetes, glycemic control improved but remains a challenge, particularly among non-Hispanic blacks and Mexican Americans.

PRIMARY FUNDING SOURCE

National Institutes of Health.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, N.I.H., Intramural

Language

eng

PubMed ID

24733192

Citation

Selvin, Elizabeth, et al. "Trends in Prevalence and Control of Diabetes in the United States, 1988-1994 and 1999-2010." Annals of Internal Medicine, vol. 160, no. 8, 2014, pp. 517-25.
Selvin E, Parrinello CM, Sacks DB, et al. Trends in prevalence and control of diabetes in the United States, 1988-1994 and 1999-2010. Ann Intern Med. 2014;160(8):517-25.
Selvin, E., Parrinello, C. M., Sacks, D. B., & Coresh, J. (2014). Trends in prevalence and control of diabetes in the United States, 1988-1994 and 1999-2010. Annals of Internal Medicine, 160(8), 517-25. https://doi.org/10.7326/M13-2411
Selvin E, et al. Trends in Prevalence and Control of Diabetes in the United States, 1988-1994 and 1999-2010. Ann Intern Med. 2014 Apr 15;160(8):517-25. PubMed PMID: 24733192.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Trends in prevalence and control of diabetes in the United States, 1988-1994 and 1999-2010. AU - Selvin,Elizabeth, AU - Parrinello,Christina M, AU - Sacks,David B, AU - Coresh,Josef, PY - 2014/4/16/entrez PY - 2014/4/16/pubmed PY - 2014/6/10/medline SP - 517 EP - 25 JF - Annals of internal medicine JO - Ann Intern Med VL - 160 IS - 8 N2 - BACKGROUND: Trends in the prevalence and control of diabetes defined by hemoglobin A1c (HbA1c) levels are important for health care policy and planning. OBJECTIVE: To update trends in the prevalence of diabetes, prediabetes, and glycemic control. DESIGN: Cross-sectional. SETTING: NHANES (National Health and Nutrition Examination Survey) in 1988-1994 and 1999-2010. PARTICIPANTS: Adults aged 20 years or older. MEASUREMENTS: We used calibrated HbA1c levels to define undiagnosed diabetes (≥6.5%); prediabetes (5.7% to 6.4%); and, among persons with diagnosed diabetes, glycemic control (<7.0% or <8.0%). Trends in HbA1c categories were compared with fasting glucose levels (≥7.0 mmol/L [≥126 mg/dL] and 5.6 to 6.9 mmol/L [100 to 125 mg/dL]). RESULTS: In 2010, approximately 21 million U.S. adults aged 20 years or older had total confirmed diabetes (self-reported diabetes or diagnostic levels for both fasting glucose and calibrated HbA1c). During 2 decades, the prevalence of total confirmed diabetes increased, but the prevalence of undiagnosed diabetes remained fairly stable, reducing the proportion of total diabetes cases that are undiagnosed to 11% in 2005-2010. The prevalence of prediabetes was lower when defined by calibrated HbA1c levels than when defined by fasting glucose levels but has increased from 5.8% in 1988-1994 to 12.4% in 2005-2010 when defined by HbA1c levels. Glycemic control improved overall, but total diabetes prevalence was greater and diabetes was less controlled among non-Hispanic blacks and Mexican Americans compared with non-Hispanic whites. LIMITATION: Cross-sectional design. CONCLUSION: Over the past 2 decades, the prevalence of total diabetes has increased substantially. However, the proportion of undiagnosed diabetes cases decreased, suggesting improvements in screening and diagnosis. Among the growing number of persons with diagnosed diabetes, glycemic control improved but remains a challenge, particularly among non-Hispanic blacks and Mexican Americans. PRIMARY FUNDING SOURCE: National Institutes of Health. SN - 1539-3704 UR - https://www.unboundmedicine.com/medline/citation/24733192/Trends_in_prevalence_and_control_of_diabetes_in_the_United_States_1988_1994_and_1999_2010_ L2 - https://www.acpjournals.org/doi/10.7326/M13-2411?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -