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Acute generalized exanthematous pustulosis induced by piroxicam: a case report.
Indian J Pharmacol. 2014 Mar-Apr; 46(2):232-3.IJ

Abstract

Acute generalized exanthematous pustulosis (AGEP) is a severe adverse cutaneous reaction characterized by an acute episode of sterile pustules over erythematous-edematous skin. The main triggering drugs are antibiotics, mainly beta-lactam and macrolides. Non-steroid anti-inflammatory drugs may rarely be responsible. We describe a case of a woman with AGEP, who presented with generalized pustulosis lesions after the use of piroxicam for renal colic. The diagnosis was confirmed by the clinical and histological correlations and the dermatosis resolved after withdrawal of the drug.

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Authors+Show Affiliations

Cherif Y
Department of Internal Medicine, Hedi Chaker University Hospital, Sfax, Tunisia.
Jallouli M
Department of Internal Medicine, Hedi Chaker University Hospital, Sfax, Tunisia.
Mseddi M
Department of Dermatology, Hedi Chaker University Hospital, Sfax, Tunisia.
Turki H
Department of Dermatology, Hedi Chaker University Hospital, Sfax, Tunisia.
Bahloul Z
Department of Internal Medicine, Hedi Chaker University Hospital, Sfax, Tunisia.

MeSH

Acute Generalized Exanthematous PustulosisAnti-Inflammatory Agents, Non-SteroidalBiopsyFemaleHumansMiddle AgedPiroxicamRenal ColicSkin

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

24741202

Citation

Cherif, Y, et al. "Acute Generalized Exanthematous Pustulosis Induced By Piroxicam: a Case Report." Indian Journal of Pharmacology, vol. 46, no. 2, 2014, pp. 232-3.
Cherif Y, Jallouli M, Mseddi M, et al. Acute generalized exanthematous pustulosis induced by piroxicam: a case report. Indian J Pharmacol. 2014;46(2):232-3.
Cherif, Y., Jallouli, M., Mseddi, M., Turki, H., & Bahloul, Z. (2014). Acute generalized exanthematous pustulosis induced by piroxicam: a case report. Indian Journal of Pharmacology, 46(2), 232-3. https://doi.org/10.4103/0253-7613.129332
Cherif Y, et al. Acute Generalized Exanthematous Pustulosis Induced By Piroxicam: a Case Report. Indian J Pharmacol. 2014 Mar-Apr;46(2):232-3. PubMed PMID: 24741202.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Acute generalized exanthematous pustulosis induced by piroxicam: a case report. AU - Cherif,Y, AU - Jallouli,Moez, AU - Mseddi,M, AU - Turki,H, AU - Bahloul,Z, PY - 2013/06/27/received PY - 2013/07/30/revised PY - 2014/01/21/accepted PY - 2014/4/18/entrez PY - 2014/4/18/pubmed PY - 2014/12/15/medline KW - Acute generalized exanthematous pustulosis KW - adverse drug reactions KW - piroxicam KW - pustulosis SP - 232 EP - 3 JF - Indian journal of pharmacology JO - Indian J Pharmacol VL - 46 IS - 2 N2 - Acute generalized exanthematous pustulosis (AGEP) is a severe adverse cutaneous reaction characterized by an acute episode of sterile pustules over erythematous-edematous skin. The main triggering drugs are antibiotics, mainly beta-lactam and macrolides. Non-steroid anti-inflammatory drugs may rarely be responsible. We describe a case of a woman with AGEP, who presented with generalized pustulosis lesions after the use of piroxicam for renal colic. The diagnosis was confirmed by the clinical and histological correlations and the dermatosis resolved after withdrawal of the drug. SN - 1998-3751 UR - https://www.unboundmedicine.com/medline/citation/24741202/Acute_generalized_exanthematous_pustulosis_induced_by_piroxicam:_a_case_report_ DB - PRIME DP - Unbound Medicine ER -