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Antibiotic prescribing practice for acute, uncomplicated respiratory tract infections in primary care settings in New Delhi, India.
Trop Med Int Health. 2014 Jul; 19(7):761-8.TM

Abstract

OBJECTIVE

To obtain information on prescribing rates and choice of antibiotics for acute, uncomplicated respiratory tract infections (RTIs) in the community.

METHODS

Antibiotic use in acute, uncomplicated RTIs consisting of common cold/sore throat/cough for not more than five days was surveyed in the community (December 2007-November 2008) using patient exit interviews at public and private facilities from four localities in New Delhi. Data were collected from 10 public sector facilities and 20 private clinics over one year. The percentage of acute, uncomplicated RTIs patients receiving antibiotics in general and using the Anatomical Therapeutic Chemical classification and the Defined Daily Dose (ATS/DDD) were analysed.

RESULTS

At public and private facilities, 45% (746/1646) and 57% (259/457) of acute, uncomplicated RTI patients were prescribed at least one antibiotic, respectively. The main antibiotic class calculated as percentage of total antibiotics DDDs/1000 prescribed to acute, uncomplicated RTI patients at private clinics was cephalosporins, J01DA (39%), followed by fluoroquinolones, J01MA (24%), penicillins, J01C (19%) and macrolides, J01FA (15%). Newer members from each class were prescribed; older antibiotics such as co-trimoxazole or tetracyclines were rarely prescribed. At public facilities, the main class of antibiotic prescribed was penicillins (31%), followed by macrolides (25%), fluoroquinolones (20%) and cephalosporins (10%).

CONCLUSIONS

Study clearly shows overuse and inappropriate choice of antibiotics for the treatment of acute, uncomplicated RTIs which are mainly due to virus and do not require antibiotic treatment. Results of the study warrant interventional strategies to promote rational use of antibiotics to decrease the overgrowing threat of antibiotic resistance.

Authors+Show Affiliations

Department of Pharmacology, V. P. Chest Institute, University of Delhi, Delhi, India.No affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24750565

Citation

Kotwani, Anita, and Kathleen Holloway. "Antibiotic Prescribing Practice for Acute, Uncomplicated Respiratory Tract Infections in Primary Care Settings in New Delhi, India." Tropical Medicine & International Health : TM & IH, vol. 19, no. 7, 2014, pp. 761-8.
Kotwani A, Holloway K. Antibiotic prescribing practice for acute, uncomplicated respiratory tract infections in primary care settings in New Delhi, India. Trop Med Int Health. 2014;19(7):761-8.
Kotwani, A., & Holloway, K. (2014). Antibiotic prescribing practice for acute, uncomplicated respiratory tract infections in primary care settings in New Delhi, India. Tropical Medicine & International Health : TM & IH, 19(7), 761-8. https://doi.org/10.1111/tmi.12327
Kotwani A, Holloway K. Antibiotic Prescribing Practice for Acute, Uncomplicated Respiratory Tract Infections in Primary Care Settings in New Delhi, India. Trop Med Int Health. 2014;19(7):761-8. PubMed PMID: 24750565.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antibiotic prescribing practice for acute, uncomplicated respiratory tract infections in primary care settings in New Delhi, India. AU - Kotwani,Anita, AU - Holloway,Kathleen, Y1 - 2014/04/22/ PY - 2014/4/23/entrez PY - 2014/4/23/pubmed PY - 2014/8/12/medline KW - Cuidados primarios KW - Infecciones del tracto respiratorio superior KW - Prescripción de antibióticos KW - Resistencia a antibióticos KW - Uso racional de antibióticos KW - antibiotic resistance KW - antibiotics prescribing KW - community pharmacists KW - farmacias comunitarias KW - infections des voies respiratoires supérieures KW - pharmaciens d'officine KW - prescription des antibiotiques KW - primary care KW - rational use of antibiotics KW - résistance aux antibiotiques KW - soins primaires KW - upper respiratory tract infections KW - utilisation rationnelle des antibiotiques SP - 761 EP - 8 JF - Tropical medicine & international health : TM & IH JO - Trop. Med. Int. Health VL - 19 IS - 7 N2 - OBJECTIVE: To obtain information on prescribing rates and choice of antibiotics for acute, uncomplicated respiratory tract infections (RTIs) in the community. METHODS: Antibiotic use in acute, uncomplicated RTIs consisting of common cold/sore throat/cough for not more than five days was surveyed in the community (December 2007-November 2008) using patient exit interviews at public and private facilities from four localities in New Delhi. Data were collected from 10 public sector facilities and 20 private clinics over one year. The percentage of acute, uncomplicated RTIs patients receiving antibiotics in general and using the Anatomical Therapeutic Chemical classification and the Defined Daily Dose (ATS/DDD) were analysed. RESULTS: At public and private facilities, 45% (746/1646) and 57% (259/457) of acute, uncomplicated RTI patients were prescribed at least one antibiotic, respectively. The main antibiotic class calculated as percentage of total antibiotics DDDs/1000 prescribed to acute, uncomplicated RTI patients at private clinics was cephalosporins, J01DA (39%), followed by fluoroquinolones, J01MA (24%), penicillins, J01C (19%) and macrolides, J01FA (15%). Newer members from each class were prescribed; older antibiotics such as co-trimoxazole or tetracyclines were rarely prescribed. At public facilities, the main class of antibiotic prescribed was penicillins (31%), followed by macrolides (25%), fluoroquinolones (20%) and cephalosporins (10%). CONCLUSIONS: Study clearly shows overuse and inappropriate choice of antibiotics for the treatment of acute, uncomplicated RTIs which are mainly due to virus and do not require antibiotic treatment. Results of the study warrant interventional strategies to promote rational use of antibiotics to decrease the overgrowing threat of antibiotic resistance. SN - 1365-3156 UR - https://www.unboundmedicine.com/medline/citation/24750565/Antibiotic_prescribing_practice_for_acute_uncomplicated_respiratory_tract_infections_in_primary_care_settings_in_New_Delhi_India_ L2 - https://doi.org/10.1111/tmi.12327 DB - PRIME DP - Unbound Medicine ER -