Tags

Type your tag names separated by a space and hit enter

Diet and risk of kidney stones in the Oxford cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC).
Eur J Epidemiol. 2014 May; 29(5):363-9.EJ

Abstract

The lifetime prevalence of kidney stones is around 10 % and incidence rates are increasing. Diet may be an important determinant of kidney stone development. Our objective was to investigate the association between diet and kidney stone risk in a population with a wide range of diets. This association was examined among 51,336 participants in the Oxford arm of the European Prospective Investigation into Cancer and Nutrition using data from Hospital Episode Statistics in England and Scottish Morbidity Records. In the cohort, 303 participants attended hospital with a new kidney stone episode. Cox proportional hazards regression was performed to calculate hazard ratios (HR) and their 95 % confidence intervals (95 % CI). Compared to those with high intake of meat (>100 g/day), the HR estimates for moderate meat-eaters (50-99 g/day), low meat-eaters (<50 g/day), fish-eaters and vegetarians were 0.80 (95 % CI 0.57-1.11), 0.52 (95 % CI 0.35-0.8), 0.73 (95 % CI 0.48-1.11) and 0.69 (95 % CI 0.48-0.98), respectively. High intakes of fresh fruit, fibre from wholegrain cereals and magnesium were also associated with a lower risk of kidney stone formation. A high intake of zinc was associated with a higher risk. In conclusion, vegetarians have a lower risk of developing kidney stones compared with those who eat a high meat diet. This information may be important to advise the public about prevention of kidney stone formation.

Authors+Show Affiliations

Department of Urology, Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK, ben.turney@nds.ox.ac.uk.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24752465

Citation

Turney, Benjamin W., et al. "Diet and Risk of Kidney Stones in the Oxford Cohort of the European Prospective Investigation Into Cancer and Nutrition (EPIC)." European Journal of Epidemiology, vol. 29, no. 5, 2014, pp. 363-9.
Turney BW, Appleby PN, Reynard JM, et al. Diet and risk of kidney stones in the Oxford cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC). Eur J Epidemiol. 2014;29(5):363-9.
Turney, B. W., Appleby, P. N., Reynard, J. M., Noble, J. G., Key, T. J., & Allen, N. E. (2014). Diet and risk of kidney stones in the Oxford cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC). European Journal of Epidemiology, 29(5), 363-9. https://doi.org/10.1007/s10654-014-9904-5
Turney BW, et al. Diet and Risk of Kidney Stones in the Oxford Cohort of the European Prospective Investigation Into Cancer and Nutrition (EPIC). Eur J Epidemiol. 2014;29(5):363-9. PubMed PMID: 24752465.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diet and risk of kidney stones in the Oxford cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC). AU - Turney,Benjamin W, AU - Appleby,Paul N, AU - Reynard,John M, AU - Noble,Jeremy G, AU - Key,Timothy J, AU - Allen,Naomi E, Y1 - 2014/04/22/ PY - 2013/12/18/received PY - 2014/04/11/accepted PY - 2014/4/23/entrez PY - 2014/4/23/pubmed PY - 2014/8/13/medline SP - 363 EP - 9 JF - European journal of epidemiology JO - Eur J Epidemiol VL - 29 IS - 5 N2 - The lifetime prevalence of kidney stones is around 10 % and incidence rates are increasing. Diet may be an important determinant of kidney stone development. Our objective was to investigate the association between diet and kidney stone risk in a population with a wide range of diets. This association was examined among 51,336 participants in the Oxford arm of the European Prospective Investigation into Cancer and Nutrition using data from Hospital Episode Statistics in England and Scottish Morbidity Records. In the cohort, 303 participants attended hospital with a new kidney stone episode. Cox proportional hazards regression was performed to calculate hazard ratios (HR) and their 95 % confidence intervals (95 % CI). Compared to those with high intake of meat (>100 g/day), the HR estimates for moderate meat-eaters (50-99 g/day), low meat-eaters (<50 g/day), fish-eaters and vegetarians were 0.80 (95 % CI 0.57-1.11), 0.52 (95 % CI 0.35-0.8), 0.73 (95 % CI 0.48-1.11) and 0.69 (95 % CI 0.48-0.98), respectively. High intakes of fresh fruit, fibre from wholegrain cereals and magnesium were also associated with a lower risk of kidney stone formation. A high intake of zinc was associated with a higher risk. In conclusion, vegetarians have a lower risk of developing kidney stones compared with those who eat a high meat diet. This information may be important to advise the public about prevention of kidney stone formation. SN - 1573-7284 UR - https://www.unboundmedicine.com/medline/citation/24752465/Diet_and_risk_of_kidney_stones_in_the_Oxford_cohort_of_the_European_Prospective_Investigation_into_Cancer_and_Nutrition__EPIC__ L2 - https://doi.org/10.1007/s10654-014-9904-5 DB - PRIME DP - Unbound Medicine ER -