Tags

Type your tag names separated by a space and hit enter

Influence of mevinolin on chloroplast terpenoids in Cannabis sativa.
Physiol Mol Biol Plants. 2014 Apr; 20(2):273-7.PM

Abstract

Plants synthesize a myriad of isoprenoid products that are required both for essential constitutive processes and for adaptive responses to the environment. Two independent pathways for the biosynthesis of isoprenoid precursors coexist within the plant cell: the cytosolic mevalonic acid (MVA) pathway and the plastidial methylerythritol phosphate (MEP) pathway. In this study, we investigated the inhibitory effect of the MVA pathway on isoprenoid biosynthesized by the MEP pathway in Cannabis sativa by treatment with mevinolin. The amount of chlorophyll a, b, and total showed to be significantly enhanced in treated plants in comparison with control plants. Also, mevinolin induced the accumulation of carotenoids and α-tocopherol in treated plants. Mevinolin caused a significant decrease in tetrahydrocannabinol (THC) content. This result show that the inhibition of the MVA pathway stimulates MEP pathway but none for all metabolites.

Authors+Show Affiliations

Department of Biology, Bahonar University, Kerman, Iran.Department of Biology, Bahonar University, Kerman, Iran.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

24757332

Citation

Mansouri, Hakimeh, and Fatemeh Salari. "Influence of Mevinolin On Chloroplast Terpenoids in Cannabis Sativa." Physiology and Molecular Biology of Plants : an International Journal of Functional Plant Biology, vol. 20, no. 2, 2014, pp. 273-7.
Mansouri H, Salari F. Influence of mevinolin on chloroplast terpenoids in Cannabis sativa. Physiol Mol Biol Plants. 2014;20(2):273-7.
Mansouri, H., & Salari, F. (2014). Influence of mevinolin on chloroplast terpenoids in Cannabis sativa. Physiology and Molecular Biology of Plants : an International Journal of Functional Plant Biology, 20(2), 273-7. https://doi.org/10.1007/s12298-014-0222-x
Mansouri H, Salari F. Influence of Mevinolin On Chloroplast Terpenoids in Cannabis Sativa. Physiol Mol Biol Plants. 2014;20(2):273-7. PubMed PMID: 24757332.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Influence of mevinolin on chloroplast terpenoids in Cannabis sativa. AU - Mansouri,Hakimeh, AU - Salari,Fatemeh, Y1 - 2014/02/26/ PY - 2013/12/18/received PY - 2014/01/20/accepted PY - 2014/4/24/entrez PY - 2014/4/24/pubmed PY - 2014/4/24/medline KW - Cannabinoids KW - Cannabis sativa KW - Mevinolin KW - Terpenoids SP - 273 EP - 7 JF - Physiology and molecular biology of plants : an international journal of functional plant biology JO - Physiol Mol Biol Plants VL - 20 IS - 2 N2 - Plants synthesize a myriad of isoprenoid products that are required both for essential constitutive processes and for adaptive responses to the environment. Two independent pathways for the biosynthesis of isoprenoid precursors coexist within the plant cell: the cytosolic mevalonic acid (MVA) pathway and the plastidial methylerythritol phosphate (MEP) pathway. In this study, we investigated the inhibitory effect of the MVA pathway on isoprenoid biosynthesized by the MEP pathway in Cannabis sativa by treatment with mevinolin. The amount of chlorophyll a, b, and total showed to be significantly enhanced in treated plants in comparison with control plants. Also, mevinolin induced the accumulation of carotenoids and α-tocopherol in treated plants. Mevinolin caused a significant decrease in tetrahydrocannabinol (THC) content. This result show that the inhibition of the MVA pathway stimulates MEP pathway but none for all metabolites. SN - 0971-5894 UR - https://www.unboundmedicine.com/medline/citation/24757332/Influence_of_mevinolin_on_chloroplast_terpenoids_in_Cannabis_sativa_ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24757332/ DB - PRIME DP - Unbound Medicine ER -
Try the Free App:
Prime PubMed app for iOS iPhone iPad
Prime PubMed app for Android
Prime PubMed is provided
free to individuals by:
Unbound Medicine.