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Successful treatment of necrobiotic xanthogranuloma with total glucosides of paeony.

Abstract

Necrobiotic xanthogranuloma (NXG) is a rare granulomatous condition that is often associated with a paraproteinemia and in some cases multiple myeloma. We report a case of isolated NXG that responded very well to total glucosides of paeony treatment. Characteristic clinical and histological features of NXG are presented, as well as a discussion regarding management and the use of glucosides of paeony. Treatment with total glucosides of paeony is an effective, safe treatment, which avoids the side effects associated with systemic corticosteroid or cytotoxic agent therapy.

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  • Authors+Show Affiliations

    ,

    Departments of Dermatology, The First Affiliated Hospital, Chongqing Medical University, Chongqing, China.

    , ,

    Source

    Dermatologic therapy 27:5 pg 304-6

    MeSH

    Dermatologic Agents
    Female
    Glucosides
    Humans
    Middle Aged
    Necrobiotic Xanthogranuloma
    Paeonia
    Phytotherapy
    Plant Extracts
    Plant Roots
    Plants, Medicinal
    Remission Induction
    Skin
    Treatment Outcome

    Pub Type(s)

    Case Reports
    Journal Article

    Language

    eng

    PubMed ID

    24774012

    Citation

    Li, Shuang, et al. "Successful Treatment of Necrobiotic Xanthogranuloma With Total Glucosides of Paeony." Dermatologic Therapy, vol. 27, no. 5, 2014, pp. 304-6.
    Li S, Chen AJ, Fang S, et al. Successful treatment of necrobiotic xanthogranuloma with total glucosides of paeony. Dermatol Ther. 2014;27(5):304-6.
    Li, S., Chen, A. J., Fang, S., & Li, H. (2014). Successful treatment of necrobiotic xanthogranuloma with total glucosides of paeony. Dermatologic Therapy, 27(5), pp. 304-6. doi:10.1111/dth.12133.
    Li S, et al. Successful Treatment of Necrobiotic Xanthogranuloma With Total Glucosides of Paeony. Dermatol Ther. 2014;27(5):304-6. PubMed PMID: 24774012.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Successful treatment of necrobiotic xanthogranuloma with total glucosides of paeony. AU - Li,Shuang, AU - Chen,Ai-Jun, AU - Fang,Sheng, AU - Li,Hui, Y1 - 2014/04/28/ PY - 2014/4/30/entrez PY - 2014/4/30/pubmed PY - 2015/6/13/medline KW - necrobiotic xanthogranuloma KW - periorbital KW - total glucosides of paeonys SP - 304 EP - 6 JF - Dermatologic therapy JO - Dermatol Ther VL - 27 IS - 5 N2 - Necrobiotic xanthogranuloma (NXG) is a rare granulomatous condition that is often associated with a paraproteinemia and in some cases multiple myeloma. We report a case of isolated NXG that responded very well to total glucosides of paeony treatment. Characteristic clinical and histological features of NXG are presented, as well as a discussion regarding management and the use of glucosides of paeony. Treatment with total glucosides of paeony is an effective, safe treatment, which avoids the side effects associated with systemic corticosteroid or cytotoxic agent therapy. SN - 1529-8019 UR - https://www.unboundmedicine.com/medline/citation/24774012/Successful_treatment_of_necrobiotic_xanthogranuloma_with_total_glucosides_of_paeony_ L2 - https://doi.org/10.1111/dth.12133 DB - PRIME DP - Unbound Medicine ER -