Tags

Type your tag names separated by a space and hit enter

Atrial longitudinal strain parameters predict left atrial reverse remodeling after mitral valve surgery: a speckle tracking echocardiography study.
Int J Cardiovasc Imaging. 2014 Aug; 30(6):1049-56.IJ

Abstract

Volume overload in chronic severe mitral regurgitation (MR) causes left atrial (LA) remodeling. Volume overload generally diminishes after mitral valve surgery and LA size and shape are expected to recover. The recovery of LA functions named as reverse remodeling is said to be related with prognosis and mortality. A few clinical and echocardiographic parameters have been reported to be associated with LA reverse remodeling. In this study, we investigated the relationship between LA peak longitudinal strain (reservoir strain) assessed with 2-dimensional speckle tracking echocardiography (2D STE) and LA reverse remodeling. 53 patients (24 females and 29 males, mean age: 45.7 ± 13.5 years) with severe MR and preserved left ventricular systolic function were included in the study. All patients had normal sinus rhythm. The etiology of MR was mitral valve prolapse (MVP) in 37 patients and rheumatic valvular disease in 16 patients. Mitral valve repair was performed in 30 patients while 23 underwent mitral valve replacement. Echocardiography was performed before the surgery and 6 months later. LA peak atrial longitudinal strain (PALS) was assessed with speckle tracking imaging. LA reverse remodeling was defined as a percent of decrease in LA volume index (LAVI). Left atrial volume index significantly decreased after surgery (58.2 ± 16.6 vs. 43.9 ± 17.2 ml/m2, p ≤ 0.001). Mean LAVI reduction was 22.5 ± 27.2%. There was no significant difference in LAVI reduction between mitral repair and replacement groups (22.1 ± 22.6 vs. 23.1 ± 32.8 %, p = 0.9). Although the decrease in LAVI was higher in MVP group than rheumatic group, it was not statistically significant (24.4 ± 26.8 vs. 18.2 ± 28.9%, p = 0.4). Correlates of LAVI reduction were preoperative LAVI (r 0.28, p = 0.039), PALS (r 0.36, p = 0.001) and age (r -0.36, p = 0.007). Furthermore, in multivariate linear regression analysis (entering models), preoperative LAVI, age and PALS were all significant predictors of LA reverse remodeling (p ≤ 0.001, p = 0.04, p = 0.001 respectively). Left atrial peak longitudinal strain measured by 2D STE, in conjunction with preoperative LAVI and age is a predictor of LA reverse remodeling in patients undergoing surgery for severe MR. We suggest that in this patient population, PALS may also be used as a preoperative prognostic marker.

Authors+Show Affiliations

Cardiology Clinic, Kartal Koşuyol Heart and Research Hospital, 34846, Kartal, Istanbul, Turkey, oz_candan@hotmail.com.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

24781032

Citation

Candan, Ozkan, et al. "Atrial Longitudinal Strain Parameters Predict Left Atrial Reverse Remodeling After Mitral Valve Surgery: a Speckle Tracking Echocardiography Study." The International Journal of Cardiovascular Imaging, vol. 30, no. 6, 2014, pp. 1049-56.
Candan O, Ozdemir N, Aung SM, et al. Atrial longitudinal strain parameters predict left atrial reverse remodeling after mitral valve surgery: a speckle tracking echocardiography study. Int J Cardiovasc Imaging. 2014;30(6):1049-56.
Candan, O., Ozdemir, N., Aung, S. M., Hatipoglu, S., Karabay, C. Y., Guler, A., Gecmen, C., Dogan, C., Omaygenc, O., & Bakal, R. B. (2014). Atrial longitudinal strain parameters predict left atrial reverse remodeling after mitral valve surgery: a speckle tracking echocardiography study. The International Journal of Cardiovascular Imaging, 30(6), 1049-56. https://doi.org/10.1007/s10554-014-0433-9
Candan O, et al. Atrial Longitudinal Strain Parameters Predict Left Atrial Reverse Remodeling After Mitral Valve Surgery: a Speckle Tracking Echocardiography Study. Int J Cardiovasc Imaging. 2014;30(6):1049-56. PubMed PMID: 24781032.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Atrial longitudinal strain parameters predict left atrial reverse remodeling after mitral valve surgery: a speckle tracking echocardiography study. AU - Candan,Ozkan, AU - Ozdemir,Nihal, AU - Aung,Soe Moe, AU - Hatipoglu,Suzan, AU - Karabay,Can Yucel, AU - Guler,Ahmet, AU - Gecmen,Cetin, AU - Dogan,Cem, AU - Omaygenc,Onur, AU - Bakal,Ruken Bengi, Y1 - 2014/04/30/ PY - 2013/12/17/received PY - 2014/04/23/accepted PY - 2014/5/1/entrez PY - 2014/5/2/pubmed PY - 2016/3/29/medline SP - 1049 EP - 56 JF - The international journal of cardiovascular imaging JO - Int J Cardiovasc Imaging VL - 30 IS - 6 N2 - Volume overload in chronic severe mitral regurgitation (MR) causes left atrial (LA) remodeling. Volume overload generally diminishes after mitral valve surgery and LA size and shape are expected to recover. The recovery of LA functions named as reverse remodeling is said to be related with prognosis and mortality. A few clinical and echocardiographic parameters have been reported to be associated with LA reverse remodeling. In this study, we investigated the relationship between LA peak longitudinal strain (reservoir strain) assessed with 2-dimensional speckle tracking echocardiography (2D STE) and LA reverse remodeling. 53 patients (24 females and 29 males, mean age: 45.7 ± 13.5 years) with severe MR and preserved left ventricular systolic function were included in the study. All patients had normal sinus rhythm. The etiology of MR was mitral valve prolapse (MVP) in 37 patients and rheumatic valvular disease in 16 patients. Mitral valve repair was performed in 30 patients while 23 underwent mitral valve replacement. Echocardiography was performed before the surgery and 6 months later. LA peak atrial longitudinal strain (PALS) was assessed with speckle tracking imaging. LA reverse remodeling was defined as a percent of decrease in LA volume index (LAVI). Left atrial volume index significantly decreased after surgery (58.2 ± 16.6 vs. 43.9 ± 17.2 ml/m2, p ≤ 0.001). Mean LAVI reduction was 22.5 ± 27.2%. There was no significant difference in LAVI reduction between mitral repair and replacement groups (22.1 ± 22.6 vs. 23.1 ± 32.8 %, p = 0.9). Although the decrease in LAVI was higher in MVP group than rheumatic group, it was not statistically significant (24.4 ± 26.8 vs. 18.2 ± 28.9%, p = 0.4). Correlates of LAVI reduction were preoperative LAVI (r 0.28, p = 0.039), PALS (r 0.36, p = 0.001) and age (r -0.36, p = 0.007). Furthermore, in multivariate linear regression analysis (entering models), preoperative LAVI, age and PALS were all significant predictors of LA reverse remodeling (p ≤ 0.001, p = 0.04, p = 0.001 respectively). Left atrial peak longitudinal strain measured by 2D STE, in conjunction with preoperative LAVI and age is a predictor of LA reverse remodeling in patients undergoing surgery for severe MR. We suggest that in this patient population, PALS may also be used as a preoperative prognostic marker. SN - 1875-8312 UR - https://www.unboundmedicine.com/medline/citation/24781032/Atrial_longitudinal_strain_parameters_predict_left_atrial_reverse_remodeling_after_mitral_valve_surgery:_a_speckle_tracking_echocardiography_study_ L2 - https://doi.org/10.1007/s10554-014-0433-9 DB - PRIME DP - Unbound Medicine ER -