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The epidemiology of osteoarthritis.

Abstract

Osteoarthritis (OA) is a leading cause of disability and its incidence is rising due to increasing obesity and an ageing population. Risk factors can be divided into person-level factors, such as age, sex, obesity, genetics, race/ethnicity and diet, and joint-level factors including injury, malalignment and abnormal loading of the joints. The interaction of these risk factors is complex and provides a challenge to the managing physician. The purpose of this review is to illustrate how each of these factors interact together to instigate incident OA as well as to outline the need for ongoing epidemiologic studies for the future prevention of both incident and progressive OA. It is only by understanding the impact of this disease and the modifiable risk factors that we will be able to truly target public health prevention interventions appropriately.

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  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Sydney Medical School, University of Sydney, Sydney, NSW, Australia. Electronic address: vjoh6545@uni.sydney.edu.au.

    Rheumatology Department, Royal North Shore Hospital and Kolling Institute, University of Sydney, Sydney, NSW, Australia. Electronic address: David.Hunter@sydney.edu.au.

    Source

    MeSH

    Aging
    Humans
    Incidence
    Osteoarthritis
    Prevalence
    Risk Factors
    United States

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't
    Review

    Language

    eng

    PubMed ID

    24792942

    Citation

    Johnson, Victoria L., and David J. Hunter. "The Epidemiology of Osteoarthritis." Best Practice & Research. Clinical Rheumatology, vol. 28, no. 1, 2014, pp. 5-15.
    Johnson VL, Hunter DJ. The epidemiology of osteoarthritis. Best Pract Res Clin Rheumatol. 2014;28(1):5-15.
    Johnson, V. L., & Hunter, D. J. (2014). The epidemiology of osteoarthritis. Best Practice & Research. Clinical Rheumatology, 28(1), pp. 5-15. doi:10.1016/j.berh.2014.01.004.
    Johnson VL, Hunter DJ. The Epidemiology of Osteoarthritis. Best Pract Res Clin Rheumatol. 2014;28(1):5-15. PubMed PMID: 24792942.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - The epidemiology of osteoarthritis. AU - Johnson,Victoria L, AU - Hunter,David J, PY - 2014/5/6/entrez PY - 2014/5/6/pubmed PY - 2014/7/23/medline KW - Aetiology KW - Epidemiology KW - Osteoarthritis SP - 5 EP - 15 JF - Best practice & research. Clinical rheumatology JO - Best Pract Res Clin Rheumatol VL - 28 IS - 1 N2 - Osteoarthritis (OA) is a leading cause of disability and its incidence is rising due to increasing obesity and an ageing population. Risk factors can be divided into person-level factors, such as age, sex, obesity, genetics, race/ethnicity and diet, and joint-level factors including injury, malalignment and abnormal loading of the joints. The interaction of these risk factors is complex and provides a challenge to the managing physician. The purpose of this review is to illustrate how each of these factors interact together to instigate incident OA as well as to outline the need for ongoing epidemiologic studies for the future prevention of both incident and progressive OA. It is only by understanding the impact of this disease and the modifiable risk factors that we will be able to truly target public health prevention interventions appropriately. SN - 1532-1770 UR - https://www.unboundmedicine.com/medline/citation/24792942/full_citation L2 - https://linkinghub.elsevier.com/retrieve/pii/S1521-6942(14)00005-9 DB - PRIME DP - Unbound Medicine ER -