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Managing coeliac disease in patients with diabetes.
Diabetes Obes Metab 2015; 17(1):3-8DO

Abstract

The association between coeliac disease and type 1 diabetes has long been established. The combination of genetic susceptibility along with a potential role for gluten in the pathogenesis of autoimmunity makes defining gluten's role in type 1 diabetes extremely important. Evidence supporting the role of a gluten-free diet to improve complications associated with type 1 diabetes is not robust. However there is evidence to support improved growth, bone density and potentially the prevention of additional autoimmune diseases in patients with coeliac disease and type 1 diabetes. The gluten free diet is expensive and challenging to adhere to in people already on a modified diet. Early identification of those who have coeliac disease and would benefit from a gluten-free diet is of utmost importance to prevent complications associated with type 1 diabetes and coeliac disease.

Authors+Show Affiliations

Center for Celiac Research, Massachusetts General Hospital and Division of Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital for Children, Boston, MA, USA.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

24814173

Citation

Leonard, M M., et al. "Managing Coeliac Disease in Patients With Diabetes." Diabetes, Obesity & Metabolism, vol. 17, no. 1, 2015, pp. 3-8.
Leonard MM, Cureton PA, Fasano A. Managing coeliac disease in patients with diabetes. Diabetes Obes Metab. 2015;17(1):3-8.
Leonard, M. M., Cureton, P. A., & Fasano, A. (2015). Managing coeliac disease in patients with diabetes. Diabetes, Obesity & Metabolism, 17(1), pp. 3-8. doi:10.1111/dom.12310.
Leonard MM, Cureton PA, Fasano A. Managing Coeliac Disease in Patients With Diabetes. Diabetes Obes Metab. 2015;17(1):3-8. PubMed PMID: 24814173.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Managing coeliac disease in patients with diabetes. AU - Leonard,M M, AU - Cureton,P A, AU - Fasano,A, Y1 - 2014/05/29/ PY - 2014/03/21/received PY - 2014/04/28/revised PY - 2014/04/29/accepted PY - 2014/5/13/entrez PY - 2014/5/13/pubmed PY - 2015/7/15/medline KW - coeliac disease KW - gluten-free diet KW - type 1 diabetes SP - 3 EP - 8 JF - Diabetes, obesity & metabolism JO - Diabetes Obes Metab VL - 17 IS - 1 N2 - The association between coeliac disease and type 1 diabetes has long been established. The combination of genetic susceptibility along with a potential role for gluten in the pathogenesis of autoimmunity makes defining gluten's role in type 1 diabetes extremely important. Evidence supporting the role of a gluten-free diet to improve complications associated with type 1 diabetes is not robust. However there is evidence to support improved growth, bone density and potentially the prevention of additional autoimmune diseases in patients with coeliac disease and type 1 diabetes. The gluten free diet is expensive and challenging to adhere to in people already on a modified diet. Early identification of those who have coeliac disease and would benefit from a gluten-free diet is of utmost importance to prevent complications associated with type 1 diabetes and coeliac disease. SN - 1463-1326 UR - https://www.unboundmedicine.com/medline/citation/24814173/Managing_coeliac_disease_in_patients_with_diabetes_ L2 - https://doi.org/10.1111/dom.12310 DB - PRIME DP - Unbound Medicine ER -