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[Dynamic changes in the hemostatic indices of diabetics during biostator control].
Vutr Boles. 1989; 28(5):41-5.VB

Abstract

In 25 patients with insulin-dependent diabetes and without microangiopathic complications the main hemostatic inhibitors antithrombin III, alpha-2-macroglobulin, and alpha-2-antiplasmin were examined before and after an optimal compensation of the carbohydrate metabolism was achieved. The patients were treated for 24 hours with the help of an artificial endocrine pancreas--biostator. The initial mean value of hyperglycemia of 15.61 mmol/l fell significantly to a mean value of 5.67 mmol/l at the end of the 24 hour treatment. During this 24 hour period the levels of the indices followed up did not change significantly. They were as follows: antithrombin III--98.48%, alpha-2-macroglobulin--112.25%, alpha-2-antiplasmin--110.68%. The lack of changes in the hemostatic inhibitors is explained by the short term biostator treatment.

Authors

Petkova M
No affiliation info available
Kamenov V
No affiliation info available
Tsanev A
No affiliation info available

MeSH

AdolescentAdultAntithrombin IIIBlood GlucoseChronic DiseaseDiabetes Mellitus, Type 1FibrinolysinHemostasisHumansInsulin Infusion SystemsTime Factorsalpha-2-Antiplasminalpha-Macroglobulins

Pub Type(s)

Comparative Study
English Abstract
Journal Article

Language

bul

PubMed ID

2482584

Citation

Petkova, M, et al. "[Dynamic Changes in the Hemostatic Indices of Diabetics During Biostator Control]." Vutreshni Bolesti, vol. 28, no. 5, 1989, pp. 41-5.
Petkova M, Kamenov V, Tsanev A. [Dynamic changes in the hemostatic indices of diabetics during biostator control]. Vutr Boles. 1989;28(5):41-5.
Petkova, M., Kamenov, V., & Tsanev, A. (1989). [Dynamic changes in the hemostatic indices of diabetics during biostator control]. Vutreshni Bolesti, 28(5), 41-5.
Petkova M, Kamenov V, Tsanev A. [Dynamic Changes in the Hemostatic Indices of Diabetics During Biostator Control]. Vutr Boles. 1989;28(5):41-5. PubMed PMID: 2482584.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Dynamic changes in the hemostatic indices of diabetics during biostator control]. AU - Petkova,M, AU - Kamenov,V, AU - Tsanev,A, PY - 1989/1/1/pubmed PY - 1989/1/1/medline PY - 1989/1/1/entrez SP - 41 EP - 5 JF - Vutreshni bolesti JO - Vutr Boles VL - 28 IS - 5 N2 - In 25 patients with insulin-dependent diabetes and without microangiopathic complications the main hemostatic inhibitors antithrombin III, alpha-2-macroglobulin, and alpha-2-antiplasmin were examined before and after an optimal compensation of the carbohydrate metabolism was achieved. The patients were treated for 24 hours with the help of an artificial endocrine pancreas--biostator. The initial mean value of hyperglycemia of 15.61 mmol/l fell significantly to a mean value of 5.67 mmol/l at the end of the 24 hour treatment. During this 24 hour period the levels of the indices followed up did not change significantly. They were as follows: antithrombin III--98.48%, alpha-2-macroglobulin--112.25%, alpha-2-antiplasmin--110.68%. The lack of changes in the hemostatic inhibitors is explained by the short term biostator treatment. SN - 0506-2772 UR - https://www.unboundmedicine.com/medline/citation/2482584/[Dynamic_changes_in_the_hemostatic_indices_of_diabetics_during_biostator_control]_ DB - PRIME DP - Unbound Medicine ER -