Tags

Type your tag names separated by a space and hit enter

Synthesis of α-trifluoromethyl ketones via the Cu-catalyzed trifluoromethylation of silyl enol ethers using an electrophilic trifluoromethylating agent.
J Org Chem. 2014 Jun 06; 79(11):5145-52.JO

Abstract

A method has been developed for the synthesis of α-trifluoromethyl ketones via the Cu-catalyzed trifluoromethylation of silyl enol ethers with an electrophilic trifluoromethylating agent, which produces a trifluoromethyl radical.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Li L
Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Road, Shanghai 200032, P. R. of China.
Chen QY
No affiliation info available
Guo Y
No affiliation info available

MeSH

AlcoholsCatalysisEthersHydrocarbons, FluorinatedKetonesMethylationMolecular StructureSilanesStereoisomerism

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24836973

Citation

Li, Lun, et al. "Synthesis of Α-trifluoromethyl Ketones Via the Cu-catalyzed Trifluoromethylation of Silyl Enol Ethers Using an Electrophilic Trifluoromethylating Agent." The Journal of Organic Chemistry, vol. 79, no. 11, 2014, pp. 5145-52.
Li L, Chen QY, Guo Y. Synthesis of α-trifluoromethyl ketones via the Cu-catalyzed trifluoromethylation of silyl enol ethers using an electrophilic trifluoromethylating agent. J Org Chem. 2014;79(11):5145-52.
Li, L., Chen, Q. Y., & Guo, Y. (2014). Synthesis of α-trifluoromethyl ketones via the Cu-catalyzed trifluoromethylation of silyl enol ethers using an electrophilic trifluoromethylating agent. The Journal of Organic Chemistry, 79(11), 5145-52. https://doi.org/10.1021/jo500713f
Li L, Chen QY, Guo Y. Synthesis of Α-trifluoromethyl Ketones Via the Cu-catalyzed Trifluoromethylation of Silyl Enol Ethers Using an Electrophilic Trifluoromethylating Agent. J Org Chem. 2014 Jun 6;79(11):5145-52. PubMed PMID: 24836973.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Synthesis of α-trifluoromethyl ketones via the Cu-catalyzed trifluoromethylation of silyl enol ethers using an electrophilic trifluoromethylating agent. AU - Li,Lun, AU - Chen,Qing-Yun, AU - Guo,Yong, Y1 - 2014/05/23/ PY - 2014/5/20/entrez PY - 2014/5/20/pubmed PY - 2015/2/11/medline SP - 5145 EP - 52 JF - The Journal of organic chemistry JO - J Org Chem VL - 79 IS - 11 N2 - A method has been developed for the synthesis of α-trifluoromethyl ketones via the Cu-catalyzed trifluoromethylation of silyl enol ethers with an electrophilic trifluoromethylating agent, which produces a trifluoromethyl radical. SN - 1520-6904 UR - https://www.unboundmedicine.com/medline/citation/24836973/Synthesis_of_α_trifluoromethyl_ketones_via_the_Cu_catalyzed_trifluoromethylation_of_silyl_enol_ethers_using_an_electrophilic_trifluoromethylating_agent_ DB - PRIME DP - Unbound Medicine ER -