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[The herbal-partitioned moxibustion for primary dysmenorrhea and it's impact on reproductive endocrinal function of patients].
Zhongguo Zhen Jiu. 2014 Mar; 34(3):209-12.ZZ

Abstract

OBJECTIVE

To explore the efficacy and the reproductive endocrinal mechanism of herbal-partitioned moxibustion in the treatment of primary dysmenorrhea.

METHODS

One hundred and seventy-one cases of primary dysmenorrhea were randomized into an herbal-partitioned moxibustion group (group A), an starch-partitioned moxibustion group (group B) and an acupuncture group (group C), 57 cases in each one. In the group A, moxibustion isolated with herbal medicine was applied to Shenque (CV 8). In the group B, moxibustion isolated with starch was used at Shenque (CV 8). In the group C, acupuncture was given at Sanyinjiao (SP 6). The changes of estradiol (E2), progesterone (P) and prostaglandin levels (PGF2alpha) were observed before and after treatment, and the therapeutic effects were compared among the 3 groups.

RESULTS

The therapeutic effect in the group A was better than those in the other two groups [compared the cured rate: 89.8% (44/49) vs 60.0% (30/50), 60.4% (32/53), both P < 0.05]. In the group A, E2 level [(110.99 +/- 12.90) pg/mL vs (83.94 +/- 8.91) pg/mL, P < 0.05] and PGF2alpha level [(24.58 +/- 3.01) pg/mL vs (14.34 +/- 1.48) pg/mL, P < 0.01] were decreased and P level was increased [(4.65 +/- 0.68) ng/mL vs (6.68 +/- 0.95) pg/mL, P < 0.05]. In the group B and C, PGF2alpha level were reduced. Concerning to the regulating of E2 and PGF2alpha levels, the results in the group A were better than those in the group B and C [(-30.16 +/- 10.20) pg/mL vs (10.79 +/- 15.01) pg/mL, (22.81 +/- 12.22) pg/mL; (-13.10 +/- 2.40) pg/mL vs (-6.52 +/- 1.88) pg/mL, (-3.14 +/- 1.19) pg/mL, (see text) P < 0.05]. Concerning to the regulation of P level, the results in the group A and B were better than that in the group C (all P < 0.05).

CONCLUSION

The herbal-partitioned moxibustion achieves the significant efficacy on primary dysmenorrhea, which could be related to regulating the reproductive endocrinal level. It decreases E2 and PGF2alpha levels and increases P level.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

24843954

Citation

Xue, Zhe, et al. "[The Herbal-partitioned Moxibustion for Primary Dysmenorrhea and It's Impact On Reproductive Endocrinal Function of Patients]." Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion, vol. 34, no. 3, 2014, pp. 209-12.
Xue Z, Liu CZ, Gao SZ, et al. [The herbal-partitioned moxibustion for primary dysmenorrhea and it's impact on reproductive endocrinal function of patients]. Zhongguo Zhen Jiu. 2014;34(3):209-12.
Xue, Z., Liu, C. Z., Gao, S. Z., & Ma, Y. X. (2014). [The herbal-partitioned moxibustion for primary dysmenorrhea and it's impact on reproductive endocrinal function of patients]. Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion, 34(3), 209-12.
Xue Z, et al. [The Herbal-partitioned Moxibustion for Primary Dysmenorrhea and It's Impact On Reproductive Endocrinal Function of Patients]. Zhongguo Zhen Jiu. 2014;34(3):209-12. PubMed PMID: 24843954.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [The herbal-partitioned moxibustion for primary dysmenorrhea and it's impact on reproductive endocrinal function of patients]. AU - Xue,Zhe, AU - Liu,Cun-Zhi, AU - Gao,Shu-Zhong, AU - Ma,Yu-Xia, PY - 2014/5/22/entrez PY - 2014/5/23/pubmed PY - 2014/6/18/medline SP - 209 EP - 12 JF - Zhongguo zhen jiu = Chinese acupuncture & moxibustion JO - Zhongguo Zhen Jiu VL - 34 IS - 3 N2 - OBJECTIVE: To explore the efficacy and the reproductive endocrinal mechanism of herbal-partitioned moxibustion in the treatment of primary dysmenorrhea. METHODS: One hundred and seventy-one cases of primary dysmenorrhea were randomized into an herbal-partitioned moxibustion group (group A), an starch-partitioned moxibustion group (group B) and an acupuncture group (group C), 57 cases in each one. In the group A, moxibustion isolated with herbal medicine was applied to Shenque (CV 8). In the group B, moxibustion isolated with starch was used at Shenque (CV 8). In the group C, acupuncture was given at Sanyinjiao (SP 6). The changes of estradiol (E2), progesterone (P) and prostaglandin levels (PGF2alpha) were observed before and after treatment, and the therapeutic effects were compared among the 3 groups. RESULTS: The therapeutic effect in the group A was better than those in the other two groups [compared the cured rate: 89.8% (44/49) vs 60.0% (30/50), 60.4% (32/53), both P < 0.05]. In the group A, E2 level [(110.99 +/- 12.90) pg/mL vs (83.94 +/- 8.91) pg/mL, P < 0.05] and PGF2alpha level [(24.58 +/- 3.01) pg/mL vs (14.34 +/- 1.48) pg/mL, P < 0.01] were decreased and P level was increased [(4.65 +/- 0.68) ng/mL vs (6.68 +/- 0.95) pg/mL, P < 0.05]. In the group B and C, PGF2alpha level were reduced. Concerning to the regulating of E2 and PGF2alpha levels, the results in the group A were better than those in the group B and C [(-30.16 +/- 10.20) pg/mL vs (10.79 +/- 15.01) pg/mL, (22.81 +/- 12.22) pg/mL; (-13.10 +/- 2.40) pg/mL vs (-6.52 +/- 1.88) pg/mL, (-3.14 +/- 1.19) pg/mL, (see text) P < 0.05]. Concerning to the regulation of P level, the results in the group A and B were better than that in the group C (all P < 0.05). CONCLUSION: The herbal-partitioned moxibustion achieves the significant efficacy on primary dysmenorrhea, which could be related to regulating the reproductive endocrinal level. It decreases E2 and PGF2alpha levels and increases P level. SN - 0255-2930 UR - https://www.unboundmedicine.com/medline/citation/24843954/[The_herbal_partitioned_moxibustion_for_primary_dysmenorrhea_and_it's_impact_on_reproductive_endocrinal_function_of_patients]_ L2 - https://medlineplus.gov/periodpain.html DB - PRIME DP - Unbound Medicine ER -