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Visceral leishmaniasis without fever in an 11-month-old infant: a rare clinical feature of Kala-azar.
Korean J Parasitol. 2014 Apr; 52(2):189-91.KJ

Abstract

Visceral leishmaniasis or kala-azar is an endemic parasitic disease in some parts of the world which is characterized by fever, splenomegaly, and pancytopenia in most of the cases. Herein we report an 11 month-old male infant with diagnosis of kala-azar who presented with pallor, hepatosplenomegaly, failure to gain weight, and no history of fever. Surprisingly, fever started after beginning of meglumine antimoniate treatment in this patient. As far as we are aware of, this is a rare presentation of visceral leishmaniasis. Therefore, clinicians especially in endemic areas are highly recommended to include kala-azar among differential diagnosis of unexplained anemia without fever to prevent misdiagnosis of this potentially fatal, but treatable condition.

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Authors+Show Affiliations

Sayyahfar S
Department of Pediatrics, Ali Asghar Children Hospital, Iran University of Medical Sciences, Tehran, Iran.
Ansari S
Department of Pediatrics, Ali Asghar Children Hospital, Iran University of Medical Sciences, Tehran, Iran.
Mohebali M
Department of Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Behnam B
Department of Genetics and Molecular Biology, Ali Asghar Children Hospital, Iran University of Medical Sciences, Tehran, Iran.

MeSH

Amphotericin BAnemiaAntiprotozoal AgentsDeoxycholic AcidDiagnosis, DifferentialDrug CombinationsEndemic DiseasesFeverHumansInfantIranLeishmania infantumLeishmaniasis, VisceralMaleMeglumineMeglumine AntimoniateOrganometallic CompoundsSplenomegaly

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

24850963

Citation

Sayyahfar, Shirin, et al. "Visceral Leishmaniasis Without Fever in an 11-month-old Infant: a Rare Clinical Feature of Kala-azar." The Korean Journal of Parasitology, vol. 52, no. 2, 2014, pp. 189-91.
Sayyahfar S, Ansari S, Mohebali M, et al. Visceral leishmaniasis without fever in an 11-month-old infant: a rare clinical feature of Kala-azar. Korean J Parasitol. 2014;52(2):189-91.
Sayyahfar, S., Ansari, S., Mohebali, M., & Behnam, B. (2014). Visceral leishmaniasis without fever in an 11-month-old infant: a rare clinical feature of Kala-azar. The Korean Journal of Parasitology, 52(2), 189-91. https://doi.org/10.3347/kjp.2014.52.2.189
Sayyahfar S, et al. Visceral Leishmaniasis Without Fever in an 11-month-old Infant: a Rare Clinical Feature of Kala-azar. Korean J Parasitol. 2014;52(2):189-91. PubMed PMID: 24850963.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Visceral leishmaniasis without fever in an 11-month-old infant: a rare clinical feature of Kala-azar. AU - Sayyahfar,Shirin, AU - Ansari,Shahla, AU - Mohebali,Mehdi, AU - Behnam,Babak, Y1 - 2014/04/18/ PY - 2013/09/06/received PY - 2013/12/27/revised PY - 2013/12/28/accepted PY - 2014/5/23/entrez PY - 2014/5/23/pubmed PY - 2015/4/22/medline KW - Leishmania infantum KW - afebrile KW - anemia KW - kala-azar KW - splenomegaly KW - visceral leishmaniasis SP - 189 EP - 91 JF - The Korean journal of parasitology JO - Korean J Parasitol VL - 52 IS - 2 N2 - Visceral leishmaniasis or kala-azar is an endemic parasitic disease in some parts of the world which is characterized by fever, splenomegaly, and pancytopenia in most of the cases. Herein we report an 11 month-old male infant with diagnosis of kala-azar who presented with pallor, hepatosplenomegaly, failure to gain weight, and no history of fever. Surprisingly, fever started after beginning of meglumine antimoniate treatment in this patient. As far as we are aware of, this is a rare presentation of visceral leishmaniasis. Therefore, clinicians especially in endemic areas are highly recommended to include kala-azar among differential diagnosis of unexplained anemia without fever to prevent misdiagnosis of this potentially fatal, but treatable condition. SN - 1738-0006 UR - https://www.unboundmedicine.com/medline/citation/24850963/Visceral_leishmaniasis_without_fever_in_an_11_month_old_infant:_a_rare_clinical_feature_of_Kala_azar_ DB - PRIME DP - Unbound Medicine ER -