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[Acquired cutis laxa associated with monoclonal gammopathy and lambda light chain deposition disease].
Dermatol Online J. 2014 May 16; 20(5):22611.DO

Abstract

Cutis laxa is a rare entity characterized clinically by redundant skin that gives an appearance of premature aging. The appearance relates to a loss of elasticity because of the destruction of elastic fibers that affects the skin and other organs. It may be associated with inflammatory conditions or diseases, such as plasma cell dyscrasias. We report the case of a 54-year-old man with acquired cutis laxa, which preceded the development of IgG-lambda monoclonal gammopathy with lambda light chain deposits in the kidney. The patient had a fatal outcome owing to severe and rapidly progressive renal failure. We emphasize the importance of recognizing a plasma cell dyscrasia in a patient with cutis laxa, although this association is rare.

Authors+Show Affiliations

Hospital Clínico Universitario de Valencia.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
English Abstract
Journal Article
Review

Language

spa

PubMed ID

24852771

Citation

Gonzalez-Rodriguez, Antonio J., et al. "[Acquired Cutis Laxa Associated With Monoclonal Gammopathy and Lambda Light Chain Deposition Disease]." Dermatology Online Journal, vol. 20, no. 5, 2014, p. 22611.
Gonzalez-Rodriguez AJ, Bella-Navarro R, Ramon Quiles D, et al. [Acquired cutis laxa associated with monoclonal gammopathy and lambda light chain deposition disease]. Dermatol Online J. 2014;20(5):22611.
Gonzalez-Rodriguez, A. J., Bella-Navarro, R., Ramon Quiles, D., & Jorda-Cuevas, E. (2014). [Acquired cutis laxa associated with monoclonal gammopathy and lambda light chain deposition disease]. Dermatology Online Journal, 20(5), 22611.
Gonzalez-Rodriguez AJ, et al. [Acquired Cutis Laxa Associated With Monoclonal Gammopathy and Lambda Light Chain Deposition Disease]. Dermatol Online J. 2014 May 16;20(5):22611. PubMed PMID: 24852771.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Acquired cutis laxa associated with monoclonal gammopathy and lambda light chain deposition disease]. AU - Gonzalez-Rodriguez,Antonio J, AU - Bella-Navarro,Rebeca, AU - Ramon Quiles,Dolores, AU - Jorda-Cuevas,Esperanza, Y1 - 2014/05/16/ PY - 2014/05/15/received PY - 2014/05/15/accepted PY - 2014/5/24/entrez PY - 2014/5/24/pubmed PY - 2015/1/6/medline SP - 22611 EP - 22611 JF - Dermatology online journal JO - Dermatol. Online J. VL - 20 IS - 5 N2 - Cutis laxa is a rare entity characterized clinically by redundant skin that gives an appearance of premature aging. The appearance relates to a loss of elasticity because of the destruction of elastic fibers that affects the skin and other organs. It may be associated with inflammatory conditions or diseases, such as plasma cell dyscrasias. We report the case of a 54-year-old man with acquired cutis laxa, which preceded the development of IgG-lambda monoclonal gammopathy with lambda light chain deposits in the kidney. The patient had a fatal outcome owing to severe and rapidly progressive renal failure. We emphasize the importance of recognizing a plasma cell dyscrasia in a patient with cutis laxa, although this association is rare. SN - 1087-2108 UR - https://www.unboundmedicine.com/medline/citation/24852771/[Acquired_cutis_laxa_associated_with_monoclonal_gammopathy_and_lambda_light_chain_deposition_disease]_ L2 - http://escholarship.org/uc/item/8nz4q9tv DB - PRIME DP - Unbound Medicine ER -