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A rare case of pituitary infarction leading to spontaneous tumour resolution and CSF-sella syndrome in an 11-year-old girl and a review of the paediatric literature.
J Pediatr Endocrinol Metab. 2014 Sep; 27(9-10):939-46.JP

Abstract

Pituitary infarction or apoplexy with spontaneous cure of the underlying pituitary adenoma is rare. In the paediatric population, we found only a few reported cases. We report a rare case of pituitary infarction progressing to CSF-sella syndrome (or empty sella) in an 11-year-old girl. She presented with sudden onset vomiting, moderate headaches, lethargy, weight loss, and tall stature above her mid-parental height. She did not have any severe symptoms of apoplexy. Her clinical and radiological findings suggested infarction of a pituitary lesion, such as a pituitary adenoma or infarction of a cystic lesion, such as a Rathke's cleft cyst. In this report, we discuss her case of probable infarction of a growth hormone secreting adenoma with a phase of accelerated growth ending up with total anterior pituitary insufficiency. The differential diagnosis and review of the rare cases of paediatric pituitary infarction in the literature will be discussed.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

24859515

Citation

Maltby, Vicki E., et al. "A Rare Case of Pituitary Infarction Leading to Spontaneous Tumour Resolution and CSF-sella Syndrome in an 11-year-old Girl and a Review of the Paediatric Literature." Journal of Pediatric Endocrinology & Metabolism : JPEM, vol. 27, no. 9-10, 2014, pp. 939-46.
Maltby VE, Crock PA, Lüdecke DK. A rare case of pituitary infarction leading to spontaneous tumour resolution and CSF-sella syndrome in an 11-year-old girl and a review of the paediatric literature. J Pediatr Endocrinol Metab. 2014;27(9-10):939-46.
Maltby, V. E., Crock, P. A., & Lüdecke, D. K. (2014). A rare case of pituitary infarction leading to spontaneous tumour resolution and CSF-sella syndrome in an 11-year-old girl and a review of the paediatric literature. Journal of Pediatric Endocrinology & Metabolism : JPEM, 27(9-10), 939-46. https://doi.org/10.1515/jpem-2014-0143
Maltby VE, Crock PA, Lüdecke DK. A Rare Case of Pituitary Infarction Leading to Spontaneous Tumour Resolution and CSF-sella Syndrome in an 11-year-old Girl and a Review of the Paediatric Literature. J Pediatr Endocrinol Metab. 2014;27(9-10):939-46. PubMed PMID: 24859515.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A rare case of pituitary infarction leading to spontaneous tumour resolution and CSF-sella syndrome in an 11-year-old girl and a review of the paediatric literature. AU - Maltby,Vicki E, AU - Crock,Patricia A, AU - Lüdecke,Dieter K, PY - 2014/04/03/received PY - 2014/04/16/accepted PY - 2014/5/27/entrez PY - 2014/5/27/pubmed PY - 2015/5/26/medline SP - 939 EP - 46 JF - Journal of pediatric endocrinology & metabolism : JPEM JO - J Pediatr Endocrinol Metab VL - 27 IS - 9-10 N2 - Pituitary infarction or apoplexy with spontaneous cure of the underlying pituitary adenoma is rare. In the paediatric population, we found only a few reported cases. We report a rare case of pituitary infarction progressing to CSF-sella syndrome (or empty sella) in an 11-year-old girl. She presented with sudden onset vomiting, moderate headaches, lethargy, weight loss, and tall stature above her mid-parental height. She did not have any severe symptoms of apoplexy. Her clinical and radiological findings suggested infarction of a pituitary lesion, such as a pituitary adenoma or infarction of a cystic lesion, such as a Rathke's cleft cyst. In this report, we discuss her case of probable infarction of a growth hormone secreting adenoma with a phase of accelerated growth ending up with total anterior pituitary insufficiency. The differential diagnosis and review of the rare cases of paediatric pituitary infarction in the literature will be discussed. SN - 2191-0251 UR - https://www.unboundmedicine.com/medline/citation/24859515/A_rare_case_of_pituitary_infarction_leading_to_spontaneous_tumour_resolution_and_CSF_sella_syndrome_in_an_11_year_old_girl_and_a_review_of_the_paediatric_literature_ DB - PRIME DP - Unbound Medicine ER -