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Detection and prevalence of drug use in arrested drivers using the Dräger Drug Test 5000 and Affiniton DrugWipe oral fluid drug screening devices.
J Anal Toxicol. 2014 Sep; 38(7):444-50.JA

Abstract

The use of oral fluid (OF) drug testing devices offers the ability to rapidly obtain a drug screening result at the time of a traffic stop. We describe an evaluation of two such devices, the Dräger Drug Test 5000 and the Affiniton DrugWipe, to detect drug use in a cohort of drivers arrested from an investigation of drug impaired driving (n = 92). Overall, 41% of these drivers were ultimately confirmed positive by mass spectrometry for the presence of one or more drugs. The most frequently detected drugs were cannabinoids (30%), benzodiazepines (11%) and cocaine (10%). Thirty-nine percent of drivers with blood alcohol concentrations >0.08 g/100 mL were found to be drug positive. Field test results obtained from OF samples were compared with collected OF and urine samples subsequently analyzed in the laboratory by gas or liquid chromatography-mass spectrometry. The Dräger Drug Test 5000 (DDT5000) and DrugWipe returned overall sensitivities of 51 and 53%, and positive predictive values of 93 and 63%, respectively. The most notable difference in performance was the DDT5000's better sensitivity in detecting marijuana use. Both devices failed to detect benzodiazepine use. Oral fluid proved to be a more effective confirmatory specimen, with more drugs being confirmed in OF than urine.

Authors+Show Affiliations

The Center for Forensic Science Research and Education, Willow Grove, PA, USA NMS Labs, Willow Grove, PA, USA Barry.Logan@nmslabs.com.The Center for Forensic Science Research and Education, Willow Grove, PA, USA.Institute for Behavior and Health Inc., Rockville, MD, USA.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

24894458

Citation

Logan, Barry K., et al. "Detection and Prevalence of Drug Use in Arrested Drivers Using the Dräger Drug Test 5000 and Affiniton DrugWipe Oral Fluid Drug Screening Devices." Journal of Analytical Toxicology, vol. 38, no. 7, 2014, pp. 444-50.
Logan BK, Mohr AL, Talpins SK. Detection and prevalence of drug use in arrested drivers using the Dräger Drug Test 5000 and Affiniton DrugWipe oral fluid drug screening devices. J Anal Toxicol. 2014;38(7):444-50.
Logan, B. K., Mohr, A. L., & Talpins, S. K. (2014). Detection and prevalence of drug use in arrested drivers using the Dräger Drug Test 5000 and Affiniton DrugWipe oral fluid drug screening devices. Journal of Analytical Toxicology, 38(7), 444-50. https://doi.org/10.1093/jat/bku050
Logan BK, Mohr AL, Talpins SK. Detection and Prevalence of Drug Use in Arrested Drivers Using the Dräger Drug Test 5000 and Affiniton DrugWipe Oral Fluid Drug Screening Devices. J Anal Toxicol. 2014;38(7):444-50. PubMed PMID: 24894458.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Detection and prevalence of drug use in arrested drivers using the Dräger Drug Test 5000 and Affiniton DrugWipe oral fluid drug screening devices. AU - Logan,Barry K, AU - Mohr,Amanda L A, AU - Talpins,Stephen K, Y1 - 2014/06/03/ PY - 2014/6/5/entrez PY - 2014/6/5/pubmed PY - 2015/4/9/medline SP - 444 EP - 50 JF - Journal of analytical toxicology JO - J Anal Toxicol VL - 38 IS - 7 N2 - The use of oral fluid (OF) drug testing devices offers the ability to rapidly obtain a drug screening result at the time of a traffic stop. We describe an evaluation of two such devices, the Dräger Drug Test 5000 and the Affiniton DrugWipe, to detect drug use in a cohort of drivers arrested from an investigation of drug impaired driving (n = 92). Overall, 41% of these drivers were ultimately confirmed positive by mass spectrometry for the presence of one or more drugs. The most frequently detected drugs were cannabinoids (30%), benzodiazepines (11%) and cocaine (10%). Thirty-nine percent of drivers with blood alcohol concentrations >0.08 g/100 mL were found to be drug positive. Field test results obtained from OF samples were compared with collected OF and urine samples subsequently analyzed in the laboratory by gas or liquid chromatography-mass spectrometry. The Dräger Drug Test 5000 (DDT5000) and DrugWipe returned overall sensitivities of 51 and 53%, and positive predictive values of 93 and 63%, respectively. The most notable difference in performance was the DDT5000's better sensitivity in detecting marijuana use. Both devices failed to detect benzodiazepine use. Oral fluid proved to be a more effective confirmatory specimen, with more drugs being confirmed in OF than urine. SN - 1945-2403 UR - https://www.unboundmedicine.com/medline/citation/24894458/Detection_and_prevalence_of_drug_use_in_arrested_drivers_using_the_Dräger_Drug_Test_5000_and_Affiniton_DrugWipe_oral_fluid_drug_screening_devices_ DB - PRIME DP - Unbound Medicine ER -