TY - JOUR T1 - Rapid profiling of phenolic compounds of green and fermented Bergenia crassifolia L. leaves by UPLC-DAD-QqQ-MS and HPLC-DAD-ESI-QTOF-MS. AU - Salminen,Juha-Pekka, AU - Shikov,Alexander N, AU - Karonen,Maarit, AU - Pozharitskaya,Olga N, AU - Kim,Jorma, AU - Makarov,Valery G, AU - Hiltunen,Raimo, AU - Galambosi,Bertalan, Y1 - 2014/06/04/ PY - 2014/6/5/entrez PY - 2014/6/5/pubmed PY - 2015/1/8/medline KW - LC-DAD-ESI-QTOF-MS KW - UPLC-DAD-QqQ-MS KW - ellagitannins KW - gallic acid KW - hydrolysable tannins SP - 1530 EP - 3 JF - Natural product research JO - Nat Prod Res VL - 28 IS - 19 N2 - Bergenia crassifolia L., Saxifragaceae, is an evergreen perennial plant known in traditional medicine of Russia, Mongolia and China. Polyphenols are responsible for the number of pharmacological effects of Bergenia. UPLC-DAD-QqQ-MS and LC-DAD-ESI-QTOF-MS were used for the rapid profiling of phenolic compounds, mainly hydrolysable tannins. Green leaves consisted of 55% ellagitannins, 29% gallic acid derivatives and 11% flavonoids, with the remaining gallic acid, arbutin, bergenin and caffeoyl quinic acid. In fermented leaves, 31% of gallic acid was found, followed with 28% ellagitannins, 18% gallic acid derivatives and 18% flavonoids, with the remaining caffeoyl quinic acid, bergenin and arbutin. Tellimagrandin I, pedunculagin, caffeoyl quinic acid, monogalloyl quinic acid, 1-O-galloylglucose and 1,2,6-tri-O-galloylglucose were identified for the very first time. SN - 1478-6427 UR - https://www.unboundmedicine.com/medline/citation/24896228/Rapid_profiling_of_phenolic_compounds_of_green_and_fermented_Bergenia_crassifolia_L__leaves_by_UPLC_DAD_QqQ_MS_and_HPLC_DAD_ESI_QTOF_MS_ DB - PRIME DP - Unbound Medicine ER -