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The traditional Chinese medicine prescription patterns of Sjögren׳s patients in Taiwan: a population-based study.
J Ethnopharmacol. 2014 Aug 08; 155(1):435-42.JE

Abstract

ETHNOPHARMACOLOGICAL RELEVANCE

Traditional Chinese medicines (TCM), when given for symptom relief, have gained widespread popularity among Sjögren׳s patients. The aim of this study was to analyze the utilization of TCM among Sjögren׳s patients in Taiwan.

MATERIALS AND METHODS

The usage, frequency of service, and the Chinese herbal products prescribed among Sjögren׳s patients were evaluated in a cohort of 1,000,000 beneficiaries recruited from the National Health Insurance Research Database. The logistic regression method was employed to estimate the odds ratios (ORs) for utilization of a TCM.

RESULTS

More than 90% of Sjögren׳s patients received TCM out-patient services at least once during the study period. Patients with secondary Sjögren׳s syndrome were more likely to seek TCM treatment than those with primary Sjögren׳s syndrome. The aOR for those suffering from at least one rheumatologic disease was 1.56 (95% CI: 1.26-1.93), those with two rheumatologic diseases was 1.98 (95% CI: 1.29-3.04), while those with three or more rheumatologic diseases was 7.86 (95% CI: 1.09-56.58). Compared to Sjögren׳s patients who used no medical treatment, the aOR for those who took one type of conventional medication was 1.55 (95% CI: 1.25-1.92), those who took two types was 1.98 (95% CI: 1.60-2.47) while those who took three or more types was 2.91 (95% CI: 2.20-3.84). Qi-Ju-Di-Huang-Wan (Lycium Berry, Chrysanthemum, and Rehmannia Pill) was the most frequently prescribed formula among Sjögren׳s patients.

CONCLUSION

Qi-Ju-Di-Huang-Wan is the most commonly prescribed Chinese herbal formula for Sjögren׳s syndrome and its effects should be taken into account by healthcare providers.

Authors+Show Affiliations

School of Medicine, Chung Shan Medical University, Department of Integrated Chinese and Western Medicine, Chung Shan Medical University Hospital, Taichung City, Taiwan; Institute of Traditional Medicine, School of Medicine, National Yang-Ming University, Taipei City 112, Taiwan.Institute of Traditional Medicine, School of Medicine, National Yang-Ming University, Taipei City 112, Taiwan; Department of Chinese Medicine, Taipei City Hospital, Ren-Ai Chinese Medicine Branch, Taipei, Taipei City 106, Taiwan.Institute of Traditional Medicine, School of Medicine, National Yang-Ming University, Taipei City 112, Taiwan; Department of Chinese Medicine, Taipei City Hospital, Yangming Branch, Taipei City 111, Taiwan. Electronic address: kareny@ms10.hinet.net.Institute of Medicine, Chung Shan Medical University, Division of Allergy, Immunology and Rheumatology, Department of Medicine, Chung Shan Medical University Hospital, Taiwan; Graduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan.Department of Oral and Maxillofacial Surgery, Mackay Memorial Hospital, Taipei, Taiwan.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24905866

Citation

Yu, Min-Chien, et al. "The Traditional Chinese Medicine Prescription Patterns of Sjögren׳s Patients in Taiwan: a Population-based Study." Journal of Ethnopharmacology, vol. 155, no. 1, 2014, pp. 435-42.
Yu MC, Lin SK, Lai JN, et al. The traditional Chinese medicine prescription patterns of Sjögren׳s patients in Taiwan: a population-based study. J Ethnopharmacol. 2014;155(1):435-42.
Yu, M. C., Lin, S. K., Lai, J. N., Wei, J. C., & Cheng, C. Y. (2014). The traditional Chinese medicine prescription patterns of Sjögren׳s patients in Taiwan: a population-based study. Journal of Ethnopharmacology, 155(1), 435-42. https://doi.org/10.1016/j.jep.2014.05.049
Yu MC, et al. The Traditional Chinese Medicine Prescription Patterns of Sjögren׳s Patients in Taiwan: a Population-based Study. J Ethnopharmacol. 2014 Aug 8;155(1):435-42. PubMed PMID: 24905866.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The traditional Chinese medicine prescription patterns of Sjögren׳s patients in Taiwan: a population-based study. AU - Yu,Min-Chien, AU - Lin,Shun-Ku, AU - Lai,Jung-Nien, AU - Wei,James Cheng-Chung, AU - Cheng,Chieh-Yuan, Y1 - 2014/06/04/ PY - 2014/02/11/received PY - 2014/05/09/revised PY - 2014/05/23/accepted PY - 2014/6/7/entrez PY - 2014/6/7/pubmed PY - 2015/4/8/medline KW - Chinese herbal product KW - National Health Insurance Research Database KW - Prescription patterns KW - Qi-Ju-Di-Huang-Wan KW - Sjögren׳s syndrome SP - 435 EP - 42 JF - Journal of ethnopharmacology JO - J Ethnopharmacol VL - 155 IS - 1 N2 - ETHNOPHARMACOLOGICAL RELEVANCE: Traditional Chinese medicines (TCM), when given for symptom relief, have gained widespread popularity among Sjögren׳s patients. The aim of this study was to analyze the utilization of TCM among Sjögren׳s patients in Taiwan. MATERIALS AND METHODS: The usage, frequency of service, and the Chinese herbal products prescribed among Sjögren׳s patients were evaluated in a cohort of 1,000,000 beneficiaries recruited from the National Health Insurance Research Database. The logistic regression method was employed to estimate the odds ratios (ORs) for utilization of a TCM. RESULTS: More than 90% of Sjögren׳s patients received TCM out-patient services at least once during the study period. Patients with secondary Sjögren׳s syndrome were more likely to seek TCM treatment than those with primary Sjögren׳s syndrome. The aOR for those suffering from at least one rheumatologic disease was 1.56 (95% CI: 1.26-1.93), those with two rheumatologic diseases was 1.98 (95% CI: 1.29-3.04), while those with three or more rheumatologic diseases was 7.86 (95% CI: 1.09-56.58). Compared to Sjögren׳s patients who used no medical treatment, the aOR for those who took one type of conventional medication was 1.55 (95% CI: 1.25-1.92), those who took two types was 1.98 (95% CI: 1.60-2.47) while those who took three or more types was 2.91 (95% CI: 2.20-3.84). Qi-Ju-Di-Huang-Wan (Lycium Berry, Chrysanthemum, and Rehmannia Pill) was the most frequently prescribed formula among Sjögren׳s patients. CONCLUSION: Qi-Ju-Di-Huang-Wan is the most commonly prescribed Chinese herbal formula for Sjögren׳s syndrome and its effects should be taken into account by healthcare providers. SN - 1872-7573 UR - https://www.unboundmedicine.com/medline/citation/24905866/The_traditional_Chinese_medicine_prescription_patterns_of_Sjögren׳s_patients_in_Taiwan:_a_population_based_study_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0378-8741(14)00418-8 DB - PRIME DP - Unbound Medicine ER -