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An extensively hydrolysed rice protein-based formula in the management of infants with cow's milk protein allergy: preliminary results after 1 month.
Arch Dis Child. 2014 Oct; 99(10):933-6.AD

Abstract

BACKGROUND

Guidelines recommend extensively hydrolysed cow's milk protein formulas (eHF) in the treatment of infants diagnosed with cow's milk protein allergy (CMPA). Extensively hydrolysed rice protein infant formulas (eRHFs) have recently become available, and could offer a valid alternative.

METHODS

A prospective trial was performed to evaluate the clinical tolerance of a new eRHF in infants with a confirmed CMPA. Patients were followed for 1 month. Clinical tolerance of the eRHF was evaluated with a symptom-based score (SBS) and growth (weight and length) was monitored.

RESULTS

Thirty-nine infants (mean age 3.4 months, range 0.5-6 months) diagnosed with CMPA were enrolled. All infants tolerated the eRHF and experienced a normal growth.

CONCLUSIONS

In accordance with current guidelines, this eRHF is tolerated by more than 90% of children with proven CMPA with a 95% CI, and is an adequate alternative to cow's milk-based eHF.

TRIAL REGISTRATION NUMBER

ClinicalTrials.gov NCT01998074.

Authors+Show Affiliations

Universitair KinderZiekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium.Universitair KinderZiekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium.Universitair KinderZiekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium.No affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Multicenter Study

Language

eng

PubMed ID

24914098

Citation

Vandenplas, Yvan, et al. "An Extensively Hydrolysed Rice Protein-based Formula in the Management of Infants With Cow's Milk Protein Allergy: Preliminary Results After 1 Month." Archives of Disease in Childhood, vol. 99, no. 10, 2014, pp. 933-6.
Vandenplas Y, De Greef E, Hauser B, et al. An extensively hydrolysed rice protein-based formula in the management of infants with cow's milk protein allergy: preliminary results after 1 month. Arch Dis Child. 2014;99(10):933-6.
Vandenplas, Y., De Greef, E., & Hauser, B. (2014). An extensively hydrolysed rice protein-based formula in the management of infants with cow's milk protein allergy: preliminary results after 1 month. Archives of Disease in Childhood, 99(10), 933-6. https://doi.org/10.1136/archdischild-2013-304727
Vandenplas Y, et al. An Extensively Hydrolysed Rice Protein-based Formula in the Management of Infants With Cow's Milk Protein Allergy: Preliminary Results After 1 Month. Arch Dis Child. 2014;99(10):933-6. PubMed PMID: 24914098.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - An extensively hydrolysed rice protein-based formula in the management of infants with cow's milk protein allergy: preliminary results after 1 month. AU - Vandenplas,Yvan, AU - De Greef,Elisabeth, AU - Hauser,Bruno, AU - ,, AU - ,, Y1 - 2014/06/09/ PY - 2014/6/11/entrez PY - 2014/6/11/pubmed PY - 2014/11/14/medline KW - Allergy KW - Gastroenterology KW - General Paediatrics KW - Nutrition SP - 933 EP - 6 JF - Archives of disease in childhood JO - Arch Dis Child VL - 99 IS - 10 N2 - BACKGROUND: Guidelines recommend extensively hydrolysed cow's milk protein formulas (eHF) in the treatment of infants diagnosed with cow's milk protein allergy (CMPA). Extensively hydrolysed rice protein infant formulas (eRHFs) have recently become available, and could offer a valid alternative. METHODS: A prospective trial was performed to evaluate the clinical tolerance of a new eRHF in infants with a confirmed CMPA. Patients were followed for 1 month. Clinical tolerance of the eRHF was evaluated with a symptom-based score (SBS) and growth (weight and length) was monitored. RESULTS: Thirty-nine infants (mean age 3.4 months, range 0.5-6 months) diagnosed with CMPA were enrolled. All infants tolerated the eRHF and experienced a normal growth. CONCLUSIONS: In accordance with current guidelines, this eRHF is tolerated by more than 90% of children with proven CMPA with a 95% CI, and is an adequate alternative to cow's milk-based eHF. TRIAL REGISTRATION NUMBER: ClinicalTrials.gov NCT01998074. SN - 1468-2044 UR - https://www.unboundmedicine.com/medline/citation/24914098/An_extensively_hydrolysed_rice_protein_based_formula_in_the_management_of_infants_with_cow's_milk_protein_allergy:_preliminary_results_after_1_month_ L2 - https://adc.bmj.com/lookup/pmidlookup?view=long&pmid=24914098 DB - PRIME DP - Unbound Medicine ER -