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2012 American Geriatrics Society Beers criteria: enhanced applicability for detecting potentially inappropriate medications in European older adults? A comparison with the Screening Tool of Older Person's Potentially Inappropriate Prescriptions.
J Am Geriatr Soc. 2014 Jul; 62(7):1217-23.JA

Abstract

OBJECTIVES

To determine the prevalence of potentially inappropriate medications (PIMs) and related factors through a comparative analysis of the Screening Tool of Older Person's Potentially Inappropriate Prescriptions (STOPP), the 2003 Beers criteria, and the 2012 AGS update of the Beers criteria.

DESIGN

Cross-sectional.

SETTING

Primary care.

PARTICIPANTS

Community-dwelling persons aged 65 and older who live on the island of Lanzarote, Spain (N = 407).

MEASUREMENTS

Sociodemographic characteristics; independence in activities of daily living; cognitive function; Geriatric Depression Scale; clinical diagnoses; and complete data on indication, dosage, and length of drug treatments. One thousand eight hundred seventh-two prescriptions were examined, and the rate of PIMs was assessed with the three criteria. The primary endpoint was the percentage of participants receiving at least one PIM. Multivariate logistic regression was used to examine the factors related to PIMs.

RESULTS

Potentially inappropriate medications were present in 24.3%, 35.4%, and 44% of participants, according to the 2003 Beers criteria, STOPP, and 2012 Beers criteria, respectively. The profile of PIMs was also different (the most frequent being benzodiazepines in both Beers criteria lists and aspirin in the STOPP). The number of drugs was associated with risk of prescribing PIMs in all three models, as was the presence of a psychological disorder in the 2003 Beers criteria (odds ratio (OR) = 2.07, 95% confidence interval (CI) = 1.26-3.40) and the 2012 Beers criteria (OR = 2.91, 95% CI = 1.83-4.66). The kappa for degree of agreement between STOPP and the 2012 Beers criteria was 0.35 (95% CI = 0.25-0.44).

CONCLUSION

The 2012 Beers criteria detected the highest number of PIMs, and given the scant overlapping with the STOPP criteria, the use of both tools may be seen as complementary.

Authors+Show Affiliations

Pharmacology and Therapeutics Department, Medical School, Málaga Biomedical Institute, University of Málaga, Málaga, Spain.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

24917083

Citation

Blanco-Reina, Encarnación, et al. "2012 American Geriatrics Society Beers Criteria: Enhanced Applicability for Detecting Potentially Inappropriate Medications in European Older Adults? a Comparison With the Screening Tool of Older Person's Potentially Inappropriate Prescriptions." Journal of the American Geriatrics Society, vol. 62, no. 7, 2014, pp. 1217-23.
Blanco-Reina E, Ariza-Zafra G, Ocaña-Riola R, et al. 2012 American Geriatrics Society Beers criteria: enhanced applicability for detecting potentially inappropriate medications in European older adults? A comparison with the Screening Tool of Older Person's Potentially Inappropriate Prescriptions. J Am Geriatr Soc. 2014;62(7):1217-23.
Blanco-Reina, E., Ariza-Zafra, G., Ocaña-Riola, R., & León-Ortiz, M. (2014). 2012 American Geriatrics Society Beers criteria: enhanced applicability for detecting potentially inappropriate medications in European older adults? A comparison with the Screening Tool of Older Person's Potentially Inappropriate Prescriptions. Journal of the American Geriatrics Society, 62(7), 1217-23. https://doi.org/10.1111/jgs.12891
Blanco-Reina E, et al. 2012 American Geriatrics Society Beers Criteria: Enhanced Applicability for Detecting Potentially Inappropriate Medications in European Older Adults? a Comparison With the Screening Tool of Older Person's Potentially Inappropriate Prescriptions. J Am Geriatr Soc. 2014;62(7):1217-23. PubMed PMID: 24917083.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - 2012 American Geriatrics Society Beers criteria: enhanced applicability for detecting potentially inappropriate medications in European older adults? A comparison with the Screening Tool of Older Person's Potentially Inappropriate Prescriptions. AU - Blanco-Reina,Encarnación, AU - Ariza-Zafra,Gabriel, AU - Ocaña-Riola,Ricardo, AU - León-Ortiz,Matilde, Y1 - 2014/06/10/ PY - 2014/6/12/entrez PY - 2014/6/12/pubmed PY - 2014/9/16/medline KW - Beers criteria KW - Screening Tool of Older Person's Potentially Inappropriate Prescriptions KW - older adults KW - potentially inappropriate medications SP - 1217 EP - 23 JF - Journal of the American Geriatrics Society JO - J Am Geriatr Soc VL - 62 IS - 7 N2 - OBJECTIVES: To determine the prevalence of potentially inappropriate medications (PIMs) and related factors through a comparative analysis of the Screening Tool of Older Person's Potentially Inappropriate Prescriptions (STOPP), the 2003 Beers criteria, and the 2012 AGS update of the Beers criteria. DESIGN: Cross-sectional. SETTING: Primary care. PARTICIPANTS: Community-dwelling persons aged 65 and older who live on the island of Lanzarote, Spain (N = 407). MEASUREMENTS: Sociodemographic characteristics; independence in activities of daily living; cognitive function; Geriatric Depression Scale; clinical diagnoses; and complete data on indication, dosage, and length of drug treatments. One thousand eight hundred seventh-two prescriptions were examined, and the rate of PIMs was assessed with the three criteria. The primary endpoint was the percentage of participants receiving at least one PIM. Multivariate logistic regression was used to examine the factors related to PIMs. RESULTS: Potentially inappropriate medications were present in 24.3%, 35.4%, and 44% of participants, according to the 2003 Beers criteria, STOPP, and 2012 Beers criteria, respectively. The profile of PIMs was also different (the most frequent being benzodiazepines in both Beers criteria lists and aspirin in the STOPP). The number of drugs was associated with risk of prescribing PIMs in all three models, as was the presence of a psychological disorder in the 2003 Beers criteria (odds ratio (OR) = 2.07, 95% confidence interval (CI) = 1.26-3.40) and the 2012 Beers criteria (OR = 2.91, 95% CI = 1.83-4.66). The kappa for degree of agreement between STOPP and the 2012 Beers criteria was 0.35 (95% CI = 0.25-0.44). CONCLUSION: The 2012 Beers criteria detected the highest number of PIMs, and given the scant overlapping with the STOPP criteria, the use of both tools may be seen as complementary. SN - 1532-5415 UR - https://www.unboundmedicine.com/medline/citation/24917083/2012_American_Geriatrics_Society_Beers_criteria:_enhanced_applicability_for_detecting_potentially_inappropriate_medications_in_European_older_adults_A_comparison_with_the_Screening_Tool_of_Older_Person's_Potentially_Inappropriate_Prescriptions_ L2 - https://doi.org/10.1111/jgs.12891 DB - PRIME DP - Unbound Medicine ER -