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Arthroplasty for cervical spondylotic myelopathy: similar results to patients with only radiculopathy at 3 years' follow-up.
J Neurosurg Spine. 2014 Sep; 21(3):400-10.JN

Abstract

OBJECT

Cervical arthroplasty has been accepted as a viable option for surgical management of cervical spondylosis or degenerative disc disease (DDD). The best candidates for cervical arthroplasty are young patients who have radiculopathy caused by herniated disc with competent facet joints. However, it remains uncertain whether arthroplasty is equally effective for patients who have cervical myelopathy caused by DDD. The aim of this study was to compare the outcomes of arthroplasty for patients with cervical spondylotic myelopathy (CSM) and patients with radiculopathy without CSM.

METHODS

A total of 151 consecutive cases involving patients with CSM or radiculopathy caused by DDD and who underwent one- or two-level cervical arthroplasty were included in this study. Clinical outcome evaluations and radiographic studies were reviewed. Clinical outcome measurements included the Visual Analog Scale (VAS) of neck and arm pain, Japanese Orthopaedic Association (JOA) scores, and the Neck Disability Index (NDI) in every patient. For patients with CSM, Nurick scores were recorded for evaluation of cervical myelopathy. Radiographic studies included lateral dynamic radiographs and CT for detection of the formation of heterotopic ossification .

RESULTS

Of the 151 consecutive patients with cervical DDD, 125 (82.8%; 72 patients in the myelopathy group and 53 in the radiculopathy group) had at least 24 months of clinical and radiographic follow-up. The mean duration of follow-up in these patients was 36.4 months (range 24-56 months). There was no difference in sex distribution between the 2 groups. However, the mean age of the patients in the myelopathy group was approximately 6 years greater than that of the radiculopathy group (53.1 vs 47.2 years, p < 0.001). The mean operation time, mean estimated blood loss, and the percentage of patients prescribed perioperative analgesic agents were similar in both groups (p = 0.754, 0.652, and 0.113, respectively). There were significant improvements in VAS neck and arm pain, JOA scores, and NDI in both groups. Nurick scores in the myelopathy group also improved significantly after surgery. In radiographic evaluations, 92.5% of patients in the radiculopathy group and 95.8% of those in the radiculopathy group retained spinal motion (no significant difference). Evaluation of CT scans showed heterotopic ossification in 34 patients (47.2%) in the myelopathy group and 25 patients (47.1%) in the radiculopathy group (p = 0.995). At a mean of over 3 years postoperatively, no secondary surgery was reported in either group.

CONCLUSIONS

The severity of myelopathy improves after cervical arthroplasty in patients with CSM caused by DDD. At 3-year follow-up, the clinical and radiographic outcomes of cervical arthroplasty in DDD patients with CSM are similar to those patients who have only cervical radiculopathy. Therefore, cervical arthroplasty is a viable option for patients with CSM caused by DDD who require anterior surgery. However, comparison with the standard surgical treatment of anterior cervical discectomy and fusion is necessary to corroborate the outcomes of arthroplasty for CSM.

Authors+Show Affiliations

Department of Neurosurgery, Neurological Institute and.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

24926929

Citation

Fay, Li-Yu, et al. "Arthroplasty for Cervical Spondylotic Myelopathy: Similar Results to Patients With Only Radiculopathy at 3 Years' Follow-up." Journal of Neurosurgery. Spine, vol. 21, no. 3, 2014, pp. 400-10.
Fay LY, Huang WC, Wu JC, et al. Arthroplasty for cervical spondylotic myelopathy: similar results to patients with only radiculopathy at 3 years' follow-up. J Neurosurg Spine. 2014;21(3):400-10.
Fay, L. Y., Huang, W. C., Wu, J. C., Chang, H. K., Tsai, T. Y., Ko, C. C., Tu, T. H., Wu, C. L., & Cheng, H. (2014). Arthroplasty for cervical spondylotic myelopathy: similar results to patients with only radiculopathy at 3 years' follow-up. Journal of Neurosurgery. Spine, 21(3), 400-10. https://doi.org/10.3171/2014.3.SPINE13387
Fay LY, et al. Arthroplasty for Cervical Spondylotic Myelopathy: Similar Results to Patients With Only Radiculopathy at 3 Years' Follow-up. J Neurosurg Spine. 2014;21(3):400-10. PubMed PMID: 24926929.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Arthroplasty for cervical spondylotic myelopathy: similar results to patients with only radiculopathy at 3 years' follow-up. AU - Fay,Li-Yu, AU - Huang,Wen-Cheng, AU - Wu,Jau-Ching, AU - Chang,Hsuan-Kan, AU - Tsai,Tzu-Yun, AU - Ko,Chin-Chu, AU - Tu,Tsung-Hsi, AU - Wu,Ching-Lan, AU - Cheng,Henrich, Y1 - 2014/06/13/ PY - 2014/6/14/entrez PY - 2014/6/14/pubmed PY - 2014/10/29/medline KW - ACDF = anterior cervical discectomy and fusion KW - CSM = cervical spondylotic myelopathy KW - DDD = degenerative disc disease KW - FDA = Food and Drug Administration KW - IDE = investigational device exemption KW - JOA = Japanese Orthopaedic Association KW - NDI = Neck Disability Index KW - OPLL = ossification of the posterior longitudinal ligament KW - VAS = visual analog scale KW - cervical arthroplasty KW - cervical spondylotic myelopathy KW - degenerative disc disease KW - heterotopic ossification KW - radiculopathy SP - 400 EP - 10 JF - Journal of neurosurgery. Spine JO - J Neurosurg Spine VL - 21 IS - 3 N2 - OBJECT: Cervical arthroplasty has been accepted as a viable option for surgical management of cervical spondylosis or degenerative disc disease (DDD). The best candidates for cervical arthroplasty are young patients who have radiculopathy caused by herniated disc with competent facet joints. However, it remains uncertain whether arthroplasty is equally effective for patients who have cervical myelopathy caused by DDD. The aim of this study was to compare the outcomes of arthroplasty for patients with cervical spondylotic myelopathy (CSM) and patients with radiculopathy without CSM. METHODS: A total of 151 consecutive cases involving patients with CSM or radiculopathy caused by DDD and who underwent one- or two-level cervical arthroplasty were included in this study. Clinical outcome evaluations and radiographic studies were reviewed. Clinical outcome measurements included the Visual Analog Scale (VAS) of neck and arm pain, Japanese Orthopaedic Association (JOA) scores, and the Neck Disability Index (NDI) in every patient. For patients with CSM, Nurick scores were recorded for evaluation of cervical myelopathy. Radiographic studies included lateral dynamic radiographs and CT for detection of the formation of heterotopic ossification . RESULTS: Of the 151 consecutive patients with cervical DDD, 125 (82.8%; 72 patients in the myelopathy group and 53 in the radiculopathy group) had at least 24 months of clinical and radiographic follow-up. The mean duration of follow-up in these patients was 36.4 months (range 24-56 months). There was no difference in sex distribution between the 2 groups. However, the mean age of the patients in the myelopathy group was approximately 6 years greater than that of the radiculopathy group (53.1 vs 47.2 years, p < 0.001). The mean operation time, mean estimated blood loss, and the percentage of patients prescribed perioperative analgesic agents were similar in both groups (p = 0.754, 0.652, and 0.113, respectively). There were significant improvements in VAS neck and arm pain, JOA scores, and NDI in both groups. Nurick scores in the myelopathy group also improved significantly after surgery. In radiographic evaluations, 92.5% of patients in the radiculopathy group and 95.8% of those in the radiculopathy group retained spinal motion (no significant difference). Evaluation of CT scans showed heterotopic ossification in 34 patients (47.2%) in the myelopathy group and 25 patients (47.1%) in the radiculopathy group (p = 0.995). At a mean of over 3 years postoperatively, no secondary surgery was reported in either group. CONCLUSIONS: The severity of myelopathy improves after cervical arthroplasty in patients with CSM caused by DDD. At 3-year follow-up, the clinical and radiographic outcomes of cervical arthroplasty in DDD patients with CSM are similar to those patients who have only cervical radiculopathy. Therefore, cervical arthroplasty is a viable option for patients with CSM caused by DDD who require anterior surgery. However, comparison with the standard surgical treatment of anterior cervical discectomy and fusion is necessary to corroborate the outcomes of arthroplasty for CSM. SN - 1547-5646 UR - https://www.unboundmedicine.com/medline/citation/24926929/Arthroplasty_for_cervical_spondylotic_myelopathy:_similar_results_to_patients_with_only_radiculopathy_at_3_years'_follow_up_ L2 - https://thejns.org/doi/10.3171/2014.3.SPINE13387 DB - PRIME DP - Unbound Medicine ER -