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Psychiatric and substance-use comorbidities associated with lifetime crack cocaine use in young adults in the general population.
Compr Psychiatry. 2014 Aug; 55(6):1369-76.CP

Abstract

OBJECTIVE

To assess the association between lifetime crack cocaine use and psychiatric (post-traumatic stress disorder, current depression, current dysthymia, generalized anxiety disorder, panic disorder with agoraphobia, social phobia, as well as SRQ scores and suicide risk) and substance-use disorders (tobacco, alcohol, cannabis, cocaine, amphetamine, inhalants, sedatives, hallucinogens and opioids) in youth in the general population of the city of Pelotas, RS.

METHOD

This was a cross-sectional population-based study, involving 1560 participants between 18 and 24 ears old. Lifetime substance use and abuse were investigated using the ASSIST inventory. Psychiatric comorbidities were assessed using the Mini-International Neuropsychiatric Interview and symptoms of common mental disorders were evaluated with the Self-Reported Questionnaire (SRQ).

RESULTS

The prevalence of lifetime crack cocaine use in the sample was 2.5%. Its use was associated with total SRW scores and the presence of post-traumatic stress disorder, antisocial personality disorder and suicide risk in the final regression model. Tobacco, alcohol, cannabis, cocaine, amphetamine and cocaine dependence were also associated with lifetime use of crack cocaine.

DISCUSSION

Youth with a history of crack cocaine use had a higher prevalence of psychiatric conditions such as post-traumatic stress disorder, as well as an increased risk of tobacco, alcohol, cannabis, cocaine, amphetamine and inhalant use and dependence.

Authors+Show Affiliations

National Institute for Translational Medicine, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil; Center for Drug and Alcohol Research, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.Graduate Program in Health and Behavior, Universidade Católica de Pelotas, Pelotas, Brazil.Graduate Program in Health and Behavior, Universidade Católica de Pelotas, Pelotas, Brazil.National Institute for Translational Medicine, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.Graduate Program in Health and Behavior, Universidade Católica de Pelotas, Pelotas, Brazil.Center for Drug and Alcohol Research, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.National Institute for Translational Medicine, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil. Electronic address: pedromaga2@gmail.com.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

24933652

Citation

Narvaez, Joana C M., et al. "Psychiatric and Substance-use Comorbidities Associated With Lifetime Crack Cocaine Use in Young Adults in the General Population." Comprehensive Psychiatry, vol. 55, no. 6, 2014, pp. 1369-76.
Narvaez JC, Jansen K, Pinheiro RT, et al. Psychiatric and substance-use comorbidities associated with lifetime crack cocaine use in young adults in the general population. Compr Psychiatry. 2014;55(6):1369-76.
Narvaez, J. C., Jansen, K., Pinheiro, R. T., Kapczinski, F., Silva, R. A., Pechansky, F., & Magalhães, P. V. (2014). Psychiatric and substance-use comorbidities associated with lifetime crack cocaine use in young adults in the general population. Comprehensive Psychiatry, 55(6), 1369-76. https://doi.org/10.1016/j.comppsych.2014.04.021
Narvaez JC, et al. Psychiatric and Substance-use Comorbidities Associated With Lifetime Crack Cocaine Use in Young Adults in the General Population. Compr Psychiatry. 2014;55(6):1369-76. PubMed PMID: 24933652.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Psychiatric and substance-use comorbidities associated with lifetime crack cocaine use in young adults in the general population. AU - Narvaez,Joana C M, AU - Jansen,Karen, AU - Pinheiro,Ricardo T, AU - Kapczinski,Flávio, AU - Silva,Ricardo A, AU - Pechansky,Flávio, AU - Magalhães,Pedro V, Y1 - 2014/05/04/ PY - 2014/02/14/received PY - 2014/04/29/revised PY - 2014/04/29/accepted PY - 2014/6/17/entrez PY - 2014/6/17/pubmed PY - 2015/4/29/medline SP - 1369 EP - 76 JF - Comprehensive psychiatry JO - Compr Psychiatry VL - 55 IS - 6 N2 - OBJECTIVE: To assess the association between lifetime crack cocaine use and psychiatric (post-traumatic stress disorder, current depression, current dysthymia, generalized anxiety disorder, panic disorder with agoraphobia, social phobia, as well as SRQ scores and suicide risk) and substance-use disorders (tobacco, alcohol, cannabis, cocaine, amphetamine, inhalants, sedatives, hallucinogens and opioids) in youth in the general population of the city of Pelotas, RS. METHOD: This was a cross-sectional population-based study, involving 1560 participants between 18 and 24 ears old. Lifetime substance use and abuse were investigated using the ASSIST inventory. Psychiatric comorbidities were assessed using the Mini-International Neuropsychiatric Interview and symptoms of common mental disorders were evaluated with the Self-Reported Questionnaire (SRQ). RESULTS: The prevalence of lifetime crack cocaine use in the sample was 2.5%. Its use was associated with total SRW scores and the presence of post-traumatic stress disorder, antisocial personality disorder and suicide risk in the final regression model. Tobacco, alcohol, cannabis, cocaine, amphetamine and cocaine dependence were also associated with lifetime use of crack cocaine. DISCUSSION: Youth with a history of crack cocaine use had a higher prevalence of psychiatric conditions such as post-traumatic stress disorder, as well as an increased risk of tobacco, alcohol, cannabis, cocaine, amphetamine and inhalant use and dependence. SN - 1532-8384 UR - https://www.unboundmedicine.com/medline/citation/24933652/Psychiatric_and_substance_use_comorbidities_associated_with_lifetime_crack_cocaine_use_in_young_adults_in_the_general_population_ DB - PRIME DP - Unbound Medicine ER -