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An uncommon case of Marine-Lenhart syndrome.
Arq Bras Endocrinol Metabol. 2014 Jun; 58(4):398-401.AB

Abstract

The term Marine-Lenhart syndrome describes the association between Graves' disease and autonomously functioning thyroid nodules (AFTN), such as toxic adenoma or toxic multinodular goiter. The two diseases may coexist or may be present at different moments in the same patient. In the literature, there are many reports on the development of Graves' disease after radioiodine treatment for AFTN, but very little information may be found on the occurrence of AFTN after radioiodine therapy for Graves' disease. We describe here the case of a female patient with Graves' disease who was successfully treated with radioiodine for Graves' disease, returning to normal thyroid function. Three years later, biochemical analysis and ultrasound examination identified a thyroid nodule that progressively increased in size. The 99mTc-pertechnetate scintigraphy showed avid uptake in the right lobule, which corresponded to a nodular lesion consistent with AFTN.

Authors+Show Affiliations

Department of Clinical and Experimental Medicine, Unit of Endocrinology, University of Messina, Italy.Department of Clinical and Experimental Medicine, Unit of Endocrinology, University of Messina, Italy.Department of Clinical and Experimental Medicine, Unit of Endocrinology, University of Messina, Italy.Department of Clinical and Experimental Medicine, Unit of Endocrinology, University of Messina, Italy.Department of Biomedical Sciences and of Morphological and Functional Images, Unit of Nuclear Medicine, University of Messina, Italy.Department of Biomedical Sciences and of Morphological and Functional Images, Unit of Nuclear Medicine, University of Messina, Italy.Department of Clinical and Experimental Medicine, Unit of Endocrinology, University of Messina, Italy.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

24936736

Citation

Giuffrida, Giuseppe, et al. "An Uncommon Case of Marine-Lenhart Syndrome." Arquivos Brasileiros De Endocrinologia E Metabologia, vol. 58, no. 4, 2014, pp. 398-401.
Giuffrida G, Giovinazzo S, Certo R, et al. An uncommon case of Marine-Lenhart syndrome. Arq Bras Endocrinol Metabol. 2014;58(4):398-401.
Giuffrida, G., Giovinazzo, S., Certo, R., Vicchio, T. M., Baldari, S., Campennì, A., & Ruggeri, R. M. (2014). An uncommon case of Marine-Lenhart syndrome. Arquivos Brasileiros De Endocrinologia E Metabologia, 58(4), 398-401.
Giuffrida G, et al. An Uncommon Case of Marine-Lenhart Syndrome. Arq Bras Endocrinol Metabol. 2014;58(4):398-401. PubMed PMID: 24936736.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - An uncommon case of Marine-Lenhart syndrome. AU - Giuffrida,Giuseppe, AU - Giovinazzo,Salvatore, AU - Certo,Rosaria, AU - Vicchio,Teresa Manuela, AU - Baldari,Sergio, AU - Campennì,Alfredo, AU - Ruggeri,Rosaria Maddalena, PY - 2013/12/10/received PY - 2014/03/03/accepted PY - 2014/6/18/entrez PY - 2014/6/18/pubmed PY - 2015/5/20/medline SP - 398 EP - 401 JF - Arquivos brasileiros de endocrinologia e metabologia JO - Arq Bras Endocrinol Metabol VL - 58 IS - 4 N2 - The term Marine-Lenhart syndrome describes the association between Graves' disease and autonomously functioning thyroid nodules (AFTN), such as toxic adenoma or toxic multinodular goiter. The two diseases may coexist or may be present at different moments in the same patient. In the literature, there are many reports on the development of Graves' disease after radioiodine treatment for AFTN, but very little information may be found on the occurrence of AFTN after radioiodine therapy for Graves' disease. We describe here the case of a female patient with Graves' disease who was successfully treated with radioiodine for Graves' disease, returning to normal thyroid function. Three years later, biochemical analysis and ultrasound examination identified a thyroid nodule that progressively increased in size. The 99mTc-pertechnetate scintigraphy showed avid uptake in the right lobule, which corresponded to a nodular lesion consistent with AFTN. SN - 1677-9487 UR - https://www.unboundmedicine.com/medline/citation/24936736/An_uncommon_case_of_Marine_Lenhart_syndrome_ L2 - https://medlineplus.gov/rarediseases.html DB - PRIME DP - Unbound Medicine ER -