Tags

Type your tag names separated by a space and hit enter

Appetite control and biomarkers of satiety with vegetarian (soy) and meat-based high-protein diets for weight loss in obese men: a randomized crossover trial.
Am J Clin Nutr 2014; 100(2):548-58AJ

Abstract

BACKGROUND

There is limited evidence with regard to the effect of different sources of protein on appetite during weight loss. Vegetarian and meat-based high-protein diets may have contrasting effects on appetite and biomarkers of protein-induced satiety.

OBJECTIVE

The aim was to assess appetite response to meat or vegetarian high-protein weight-loss (HPWL) diets in obese men to monitor plasma amino acid profile and gut peptide response as potential satiety biomarkers.

DESIGN

Twenty obese [body mass index (in kg/m²): 34.8] men participated in a dietary intervention study. After 3 d of a maintenance diet, they were provided in a crossover design with either a vegetarian HPWL (Soy-HPWL) or a meat-based HPWL (Meat-HPWL) diet for 2 wk. Both diets comprised 30% protein, 30% fat, and 40% carbohydrate, provided to measured resting metabolic rate. Body weight and the motivation to eat were measured daily. Plasma satiety biomarkers were collected during a test-meal challenge (5 h) at the end of each diet period.

RESULTS

Over the 2 wk, subjects lost, on average, 2.41 and 2.27 kg with consumption of the Soy- and Meat-HPWL diets, respectively [P = 0.352; SE of the difference (SED): 0.1]. ANOVA confirmed that subjectively rated hunger (P = 0.569; SED: 3.8), fullness (P = 0.404; SED: 4.1), desire to eat (P = 0.356; SED: 3.7), preservation of lean body mass (P = 0.334; SED: 0.2), and loss of percentage fat mass (P = 0.179; SED: 0.2) did not differ between the 2 HPWL diets. There were differences in absolute concentrations of ghrelin and peptide YY between the 2 HPWL diets, although the response as net area under the curve was not different.

CONCLUSIONS

Appetite control and weight loss were similar for both HPWL diets. Gut hormone profile was similar between the diets, which suggests that vegetarian diets can be as effective as meat-based diets for appetite control during weight loss.

Authors+Show Affiliations

From the Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen, United Kingdom (MN, CF, and AMJ), and Biomathematics and Statistics Scotland, Aberdeen, United Kingdom (GH).From the Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen, United Kingdom (MN, CF, and AMJ), and Biomathematics and Statistics Scotland, Aberdeen, United Kingdom (GH).From the Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen, United Kingdom (MN, CF, and AMJ), and Biomathematics and Statistics Scotland, Aberdeen, United Kingdom (GH).From the Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen, United Kingdom (MN, CF, and AMJ), and Biomathematics and Statistics Scotland, Aberdeen, United Kingdom (GH).

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24944057

Citation

Neacsu, Madalina, et al. "Appetite Control and Biomarkers of Satiety With Vegetarian (soy) and Meat-based High-protein Diets for Weight Loss in Obese Men: a Randomized Crossover Trial." The American Journal of Clinical Nutrition, vol. 100, no. 2, 2014, pp. 548-58.
Neacsu M, Fyfe C, Horgan G, et al. Appetite control and biomarkers of satiety with vegetarian (soy) and meat-based high-protein diets for weight loss in obese men: a randomized crossover trial. Am J Clin Nutr. 2014;100(2):548-58.
Neacsu, M., Fyfe, C., Horgan, G., & Johnstone, A. M. (2014). Appetite control and biomarkers of satiety with vegetarian (soy) and meat-based high-protein diets for weight loss in obese men: a randomized crossover trial. The American Journal of Clinical Nutrition, 100(2), pp. 548-58. doi:10.3945/ajcn.113.077503.
Neacsu M, et al. Appetite Control and Biomarkers of Satiety With Vegetarian (soy) and Meat-based High-protein Diets for Weight Loss in Obese Men: a Randomized Crossover Trial. Am J Clin Nutr. 2014;100(2):548-58. PubMed PMID: 24944057.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Appetite control and biomarkers of satiety with vegetarian (soy) and meat-based high-protein diets for weight loss in obese men: a randomized crossover trial. AU - Neacsu,Madalina, AU - Fyfe,Claire, AU - Horgan,Graham, AU - Johnstone,Alexandra M, Y1 - 2014/06/18/ PY - 2014/6/20/entrez PY - 2014/6/20/pubmed PY - 2015/4/22/medline SP - 548 EP - 58 JF - The American journal of clinical nutrition JO - Am. J. Clin. Nutr. VL - 100 IS - 2 N2 - BACKGROUND: There is limited evidence with regard to the effect of different sources of protein on appetite during weight loss. Vegetarian and meat-based high-protein diets may have contrasting effects on appetite and biomarkers of protein-induced satiety. OBJECTIVE: The aim was to assess appetite response to meat or vegetarian high-protein weight-loss (HPWL) diets in obese men to monitor plasma amino acid profile and gut peptide response as potential satiety biomarkers. DESIGN: Twenty obese [body mass index (in kg/m²): 34.8] men participated in a dietary intervention study. After 3 d of a maintenance diet, they were provided in a crossover design with either a vegetarian HPWL (Soy-HPWL) or a meat-based HPWL (Meat-HPWL) diet for 2 wk. Both diets comprised 30% protein, 30% fat, and 40% carbohydrate, provided to measured resting metabolic rate. Body weight and the motivation to eat were measured daily. Plasma satiety biomarkers were collected during a test-meal challenge (5 h) at the end of each diet period. RESULTS: Over the 2 wk, subjects lost, on average, 2.41 and 2.27 kg with consumption of the Soy- and Meat-HPWL diets, respectively [P = 0.352; SE of the difference (SED): 0.1]. ANOVA confirmed that subjectively rated hunger (P = 0.569; SED: 3.8), fullness (P = 0.404; SED: 4.1), desire to eat (P = 0.356; SED: 3.7), preservation of lean body mass (P = 0.334; SED: 0.2), and loss of percentage fat mass (P = 0.179; SED: 0.2) did not differ between the 2 HPWL diets. There were differences in absolute concentrations of ghrelin and peptide YY between the 2 HPWL diets, although the response as net area under the curve was not different. CONCLUSIONS: Appetite control and weight loss were similar for both HPWL diets. Gut hormone profile was similar between the diets, which suggests that vegetarian diets can be as effective as meat-based diets for appetite control during weight loss. SN - 1938-3207 UR - https://www.unboundmedicine.com/medline/citation/24944057/Appetite_control_and_biomarkers_of_satiety_with_vegetarian__soy__and_meat_based_high_protein_diets_for_weight_loss_in_obese_men:_a_randomized_crossover_trial_ L2 - https://academic.oup.com/ajcn/article-lookup/doi/10.3945/ajcn.113.077503 DB - PRIME DP - Unbound Medicine ER -