Tags

Type your tag names separated by a space and hit enter

Placement of prophylactic pancreatic stents to prevent post-endoscopic retrograde cholangiopancreatography pancreatitis in high-risk patients: a meta-analysis.
World J Gastroenterol 2014; 20(22):7040-8WJ

Abstract

AIM

To assess the effectiveness of pancreatic stents for preventing pancreatitis in high-risk patients after endoscopic retrograde cholangiopancreatography (ERCP).

METHODS

PubMed, Embase, Science Citation Index, and Cochrane Controlled Trials Register were searched to identify relevant trials published in English. Inclusion and exclusion criteria were used to screen for suitable studies. Two reviewers independently judged the study eligibility while screening the citations. The methodological quality of the included trials was assessed using the Jadad scoring system. All results were expressed as OR and 95%CI. Data were analyzed using Stata12.0 software.

RESULTS

Ten eligible randomized controlled trials were selected, including 1176 patients. A fixed-effects model in meta-analysis supported that pancreatic duct stents significantly decreased the incidence of post-ERCP pancreatitis (PEP) in high-risk patients (OR = 0.25; 95%CI: 0.17-0.38; P < 0.001). Pancreatic stents also alleviated the severity of PEP (mild pancreatitis after ERCP: OR = 0.33; 95%CI: 0.21-0.54; P < 0.001; moderate pancreatitis after ERCP: OR = 0.30; 95%CI: 0.13-0.67; P = 0.004). The result of severe pancreatitis after ERCP was handled more rigorously (OR = 0.24; 95%CI: 0.05-1.16; P = 0.077). Serum amylase levels were not different between patients with pancreatic stents and control patients (OR = 1.08; 95%CI: 0.82-1.41; P = 0.586).

CONCLUSION

Placement of prophylactic pancreatic stents may lower the incidence of post-ERCP pancreatitis in high-risk patients and alleviate the severity of this condition.

Authors+Show Affiliations

Qing-Qing Shi, Guo-Du Tang, Xiao-Ping Lv, Department of Gastroenterology, the First Affiliated Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China.Qing-Qing Shi, Guo-Du Tang, Xiao-Ping Lv, Department of Gastroenterology, the First Affiliated Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China.Qing-Qing Shi, Guo-Du Tang, Xiao-Ping Lv, Department of Gastroenterology, the First Affiliated Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China.Qing-Qing Shi, Guo-Du Tang, Xiao-Ping Lv, Department of Gastroenterology, the First Affiliated Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China.Qing-Qing Shi, Guo-Du Tang, Xiao-Ping Lv, Department of Gastroenterology, the First Affiliated Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China.

Pub Type(s)

Journal Article
Meta-Analysis
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

24944500

Citation

Shi, Qing-Qing, et al. "Placement of Prophylactic Pancreatic Stents to Prevent Post-endoscopic Retrograde Cholangiopancreatography Pancreatitis in High-risk Patients: a Meta-analysis." World Journal of Gastroenterology, vol. 20, no. 22, 2014, pp. 7040-8.
Shi QQ, Ning XY, Zhan LL, et al. Placement of prophylactic pancreatic stents to prevent post-endoscopic retrograde cholangiopancreatography pancreatitis in high-risk patients: a meta-analysis. World J Gastroenterol. 2014;20(22):7040-8.
Shi, Q. Q., Ning, X. Y., Zhan, L. L., Tang, G. D., & Lv, X. P. (2014). Placement of prophylactic pancreatic stents to prevent post-endoscopic retrograde cholangiopancreatography pancreatitis in high-risk patients: a meta-analysis. World Journal of Gastroenterology, 20(22), pp. 7040-8. doi:10.3748/wjg.v20.i22.7040.
Shi QQ, et al. Placement of Prophylactic Pancreatic Stents to Prevent Post-endoscopic Retrograde Cholangiopancreatography Pancreatitis in High-risk Patients: a Meta-analysis. World J Gastroenterol. 2014 Jun 14;20(22):7040-8. PubMed PMID: 24944500.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Placement of prophylactic pancreatic stents to prevent post-endoscopic retrograde cholangiopancreatography pancreatitis in high-risk patients: a meta-analysis. AU - Shi,Qing-Qing, AU - Ning,Xiao-Yi, AU - Zhan,Ling-Ling, AU - Tang,Guo-Du, AU - Lv,Xiao-Ping, PY - 2013/10/23/received PY - 2014/01/10/revised PY - 2014/03/05/accepted PY - 2014/6/20/entrez PY - 2014/6/20/pubmed PY - 2015/4/11/medline KW - Endoscopic retrograde cholangiopancreatography KW - Hyperamylasemia KW - Meta-analysis KW - Pancreatic stent KW - Pancreatitis SP - 7040 EP - 8 JF - World journal of gastroenterology JO - World J. Gastroenterol. VL - 20 IS - 22 N2 - AIM: To assess the effectiveness of pancreatic stents for preventing pancreatitis in high-risk patients after endoscopic retrograde cholangiopancreatography (ERCP). METHODS: PubMed, Embase, Science Citation Index, and Cochrane Controlled Trials Register were searched to identify relevant trials published in English. Inclusion and exclusion criteria were used to screen for suitable studies. Two reviewers independently judged the study eligibility while screening the citations. The methodological quality of the included trials was assessed using the Jadad scoring system. All results were expressed as OR and 95%CI. Data were analyzed using Stata12.0 software. RESULTS: Ten eligible randomized controlled trials were selected, including 1176 patients. A fixed-effects model in meta-analysis supported that pancreatic duct stents significantly decreased the incidence of post-ERCP pancreatitis (PEP) in high-risk patients (OR = 0.25; 95%CI: 0.17-0.38; P < 0.001). Pancreatic stents also alleviated the severity of PEP (mild pancreatitis after ERCP: OR = 0.33; 95%CI: 0.21-0.54; P < 0.001; moderate pancreatitis after ERCP: OR = 0.30; 95%CI: 0.13-0.67; P = 0.004). The result of severe pancreatitis after ERCP was handled more rigorously (OR = 0.24; 95%CI: 0.05-1.16; P = 0.077). Serum amylase levels were not different between patients with pancreatic stents and control patients (OR = 1.08; 95%CI: 0.82-1.41; P = 0.586). CONCLUSION: Placement of prophylactic pancreatic stents may lower the incidence of post-ERCP pancreatitis in high-risk patients and alleviate the severity of this condition. SN - 2219-2840 UR - https://www.unboundmedicine.com/medline/citation/24944500/Placement_of_prophylactic_pancreatic_stents_to_prevent_post_endoscopic_retrograde_cholangiopancreatography_pancreatitis_in_high_risk_patients:_a_meta_analysis_ L2 - http://www.wjgnet.com/1007-9327/full/v20/i22/7040.htm DB - PRIME DP - Unbound Medicine ER -