Tags

Type your tag names separated by a space and hit enter

Pigmented rice bran and plant sterol combination reduces serum lipids in overweight and obese adults.
J Am Coll Nutr 2014; 33(3):231-8JA

Abstract

OBJECTIVE

This study investigated the dietary effect of including pigmented rice bran with or without plant sterols on lipid profiles during energy restriction-induced weight loss in overweight and obese adults not taking cholesterol-lowering medication. In addition, the study examined the effect of intervention on biomarkers of oxidative stress and inflammation.

METHODS

A group of 24 overweight and obese adults (age: 43 ± 6 years, body mass index 32 ± 1 kg/m(2), 18 females) were randomized to a 25% calorie-restricted diet containing either pigmented rice bran (RB) or the RB with addition of plant sterols (RB+PS) snack bars for 8 weeks. The individualized nutrient-balanced diet contained ∼70% of daily energy needs assessed from indirect calorimetry measured resting energy expenditure (EE) and physical activity-related EE assessed using accelerometry. Anthropometrics, blood pressure, blood lipids, glucose, urinary F2-isoprostanes, C-reactive protein, insulin, and leptin were measured at baseline and after 8 weeks of intervention.

RESULTS

Participants lost approximately 4.7 ± 2.2 kg (p < 0.001). Weight loss was not significant between the RB+PS and RB group (p = 0.056). Changes in body fat corresponded to changes in body weight. Average decrease in total cholesterol was significantly higher in the RB+PS group than in the RB group (difference 36 ± 25 g/dL vs 7 ± 16 g/dL; p = 0.044). A similar pattern was observed for the decrease in low-density lipoprotein (LDL) cholesterol (difference 22.3 ± 25.2 g/dL vs 4.4 ± 18.9 g/dL; p = 0.062). Changes in systolic blood pressure, serum levels of leptin, and F2-isoprostanes were significant between baseline values and after 8 weeks on the diet in both groups (p < 0.05) but did not differ between the 2 groups.

CONCLUSIONS

A nutrient-balanced and energy-restricted diet supplemented with rice bran and plant sterols resulted in a significant decrease in total and LDL cholesterol in overweight and obese adults.

Authors+Show Affiliations

a Nutritional Sciences (N.H.), and College of Public Health, Epidemiology and Biostatics (B.T.P.), University of Arizona , Tucson , Arizona ; Department of Food Nutrition and Health , University of British Columbia , Vancouver , British Columbia , CANADA (D.D.K., J.Z.); Department of Medicine, Clinical Research Center , Vanderbilt University , Nashville , Tennessee (C.M.D., M.S.B.); Department of Human Nutrition, Faculty of Food Technology , Agricultural University of Krakow , Krakow , POLAND (A.K.).No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

24955613

Citation

Hongu, Nobuko, et al. "Pigmented Rice Bran and Plant Sterol Combination Reduces Serum Lipids in Overweight and Obese Adults." Journal of the American College of Nutrition, vol. 33, no. 3, 2014, pp. 231-8.
Hongu N, Kitts DD, Zawistowski J, et al. Pigmented rice bran and plant sterol combination reduces serum lipids in overweight and obese adults. J Am Coll Nutr. 2014;33(3):231-8.
Hongu, N., Kitts, D. D., Zawistowski, J., Dossett, C. M., Kopeć, A., Pope, B. T., & Buchowski, M. S. (2014). Pigmented rice bran and plant sterol combination reduces serum lipids in overweight and obese adults. Journal of the American College of Nutrition, 33(3), pp. 231-8. doi:10.1080/07315724.2013.869772.
Hongu N, et al. Pigmented Rice Bran and Plant Sterol Combination Reduces Serum Lipids in Overweight and Obese Adults. J Am Coll Nutr. 2014;33(3):231-8. PubMed PMID: 24955613.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pigmented rice bran and plant sterol combination reduces serum lipids in overweight and obese adults. AU - Hongu,Nobuko, AU - Kitts,David D, AU - Zawistowski,Jerzy, AU - Dossett,Cynthia M, AU - Kopeć,Aneta, AU - Pope,Benjamin T, AU - Buchowski,Maciej S, PY - 2014/6/24/entrez PY - 2014/6/24/pubmed PY - 2015/2/6/medline KW - bioactive compounds KW - clinical trials KW - diets KW - general nutrition KW - obesity KW - preventative nutrition and chronic disease KW - supplements and functional foods SP - 231 EP - 8 JF - Journal of the American College of Nutrition JO - J Am Coll Nutr VL - 33 IS - 3 N2 - OBJECTIVE: This study investigated the dietary effect of including pigmented rice bran with or without plant sterols on lipid profiles during energy restriction-induced weight loss in overweight and obese adults not taking cholesterol-lowering medication. In addition, the study examined the effect of intervention on biomarkers of oxidative stress and inflammation. METHODS: A group of 24 overweight and obese adults (age: 43 ± 6 years, body mass index 32 ± 1 kg/m(2), 18 females) were randomized to a 25% calorie-restricted diet containing either pigmented rice bran (RB) or the RB with addition of plant sterols (RB+PS) snack bars for 8 weeks. The individualized nutrient-balanced diet contained ∼70% of daily energy needs assessed from indirect calorimetry measured resting energy expenditure (EE) and physical activity-related EE assessed using accelerometry. Anthropometrics, blood pressure, blood lipids, glucose, urinary F2-isoprostanes, C-reactive protein, insulin, and leptin were measured at baseline and after 8 weeks of intervention. RESULTS: Participants lost approximately 4.7 ± 2.2 kg (p < 0.001). Weight loss was not significant between the RB+PS and RB group (p = 0.056). Changes in body fat corresponded to changes in body weight. Average decrease in total cholesterol was significantly higher in the RB+PS group than in the RB group (difference 36 ± 25 g/dL vs 7 ± 16 g/dL; p = 0.044). A similar pattern was observed for the decrease in low-density lipoprotein (LDL) cholesterol (difference 22.3 ± 25.2 g/dL vs 4.4 ± 18.9 g/dL; p = 0.062). Changes in systolic blood pressure, serum levels of leptin, and F2-isoprostanes were significant between baseline values and after 8 weeks on the diet in both groups (p < 0.05) but did not differ between the 2 groups. CONCLUSIONS: A nutrient-balanced and energy-restricted diet supplemented with rice bran and plant sterols resulted in a significant decrease in total and LDL cholesterol in overweight and obese adults. SN - 1541-1087 UR - https://www.unboundmedicine.com/medline/citation/24955613/Pigmented_rice_bran_and_plant_sterol_combination_reduces_serum_lipids_in_overweight_and_obese_adults_ L2 - http://www.tandfonline.com/doi/full/10.1080/07315724.2013.869772 DB - PRIME DP - Unbound Medicine ER -