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Granuloma inguinale mimicking as squamous cell carcinoma of penis.
Indian J Sex Transm Dis AIDS. 2014 Jan; 35(1):56-8.IJ

Abstract

Granuloma inguinale (GI) is an acquired chronic, slowly progressive, mildly contagious disease of venereal origin, characterized by granulomatous ulceration of the genitalia and neighboring sites, with little or no tendency to spontaneous healing caused by Klebsiella (Calymmatobacterium) granulomatis. A 55-year-old male presented with fissured, foul smelling, fungating growth over prepuce with phimosis mimicking squamous cell carcinoma (SCC) without lymphadenopathy. It started with painless papulonodular showed pseudoepitheliomatous hyperplasia, infiltration in dermis, acanthosis and vacuolated macrophages suggestive of GI and not showing any histopathological features of SCC. Patient was successfully treated by giving cotrimoxazole twice a day for 21 days. Here, we presented a case of GI mimicking SCC of penis, which was diagnosed on basis of histopathology and treated with excision followed by medical therapy with cotrimoxazole.

Authors+Show Affiliations

Department of Dermatology, Pramukhswami Medical College, Karamsad, Anand, Gujarat, India.Department of Dermatology, Pramukhswami Medical College, Karamsad, Anand, Gujarat, India.Department of Dermatology, Pramukhswami Medical College, Karamsad, Anand, Gujarat, India.

Pub Type(s)

Case Reports

Language

eng

PubMed ID

24958990

Citation

Pilani, Abhishek, et al. "Granuloma Inguinale Mimicking as Squamous Cell Carcinoma of Penis." Indian Journal of Sexually Transmitted Diseases and AIDS, vol. 35, no. 1, 2014, pp. 56-8.
Pilani A, Vora R, Anjaneyan G. Granuloma inguinale mimicking as squamous cell carcinoma of penis. Indian J Sex Transm Dis AIDS. 2014;35(1):56-8.
Pilani, A., Vora, R., & Anjaneyan, G. (2014). Granuloma inguinale mimicking as squamous cell carcinoma of penis. Indian Journal of Sexually Transmitted Diseases and AIDS, 35(1), 56-8. https://doi.org/10.4103/0253-7184.132433
Pilani A, Vora R, Anjaneyan G. Granuloma Inguinale Mimicking as Squamous Cell Carcinoma of Penis. Indian J Sex Transm Dis AIDS. 2014;35(1):56-8. PubMed PMID: 24958990.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Granuloma inguinale mimicking as squamous cell carcinoma of penis. AU - Pilani,Abhishek, AU - Vora,Rita, AU - Anjaneyan,Gopikrishnan, PY - 2014/6/25/entrez PY - 2014/6/25/pubmed PY - 2014/6/25/medline KW - Granuloma inguinale KW - pseudoepitheliomatous hyperplasia KW - squamous cell carcinoma of penis SP - 56 EP - 8 JF - Indian journal of sexually transmitted diseases and AIDS JO - Indian J Sex Transm Dis AIDS VL - 35 IS - 1 N2 - Granuloma inguinale (GI) is an acquired chronic, slowly progressive, mildly contagious disease of venereal origin, characterized by granulomatous ulceration of the genitalia and neighboring sites, with little or no tendency to spontaneous healing caused by Klebsiella (Calymmatobacterium) granulomatis. A 55-year-old male presented with fissured, foul smelling, fungating growth over prepuce with phimosis mimicking squamous cell carcinoma (SCC) without lymphadenopathy. It started with painless papulonodular showed pseudoepitheliomatous hyperplasia, infiltration in dermis, acanthosis and vacuolated macrophages suggestive of GI and not showing any histopathological features of SCC. Patient was successfully treated by giving cotrimoxazole twice a day for 21 days. Here, we presented a case of GI mimicking SCC of penis, which was diagnosed on basis of histopathology and treated with excision followed by medical therapy with cotrimoxazole. SN - 2589-0557 UR - https://www.unboundmedicine.com/medline/citation/24958990/Granuloma_inguinale_mimicking_as_squamous_cell_carcinoma_of_penis. L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24958990/ DB - PRIME DP - Unbound Medicine ER -
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