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Behavioral weight loss for the management of menopausal hot flashes: a pilot study.
Menopause. 2015 Jan; 22(1):59-65.M

Abstract

OBJECTIVE

Although adiposity has been considered to be protective against hot flashes, newer data suggest positive relationships between hot flashes and adiposity. No studies have been specifically designed to test whether weight loss reduces hot flashes. This pilot study aimed to evaluate the feasibility, acceptability, and initial efficacy of behavioral weight loss in reducing hot flashes.

METHODS

Forty overweight or obese women with hot flashes (≥ 4 hot flashes/d) were randomized to either behavioral weight loss intervention or wait-list control. Hot flashes were assessed before and after intervention via physiologic monitoring, diary, and questionnaire. Comparisons of changes in hot flashes and anthropometrics between conditions were performed via Wilcoxon tests.

RESULTS

Study retention (83%) and intervention satisfaction (93.8%) were high. Most women (74.1%) reported that hot flash reduction was a major motivator for losing weight. Women randomized to the weight loss intervention lost more weight (-8.86 kg) than did women randomized to control (+0.23 kg; P < 0.0001). Women randomized to weight loss also showed greater reductions in questionnaire-reported hot flashes (2-wk hot flashes, -63.0) than did women in the control group (-28.0; P = 0.03)-a difference not demonstrated in other hot flash measures. Reductions in weight and hot flashes were significantly correlated (eg, r = 0.47, P = 0.006).

CONCLUSIONS

This pilot study shows a behavioral weight loss program that is feasible, acceptable, and effective in producing weight loss among overweight or obese women with hot flashes. Findings indicate the importance of a larger study designed to test behavioral weight loss for hot flash reduction. Hot flash management could motivate women to engage in this health-promoting behavior.

Authors+Show Affiliations

From the 1Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA; 2Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA; Departments of 3Psychology and 4Medicine, University of Pittsburgh, Pittsburgh, PA; and 5Mental Health Care Line, Michael E. DeBakey VA Medical Center, Houston, TX.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

24977456

Citation

Thurston, Rebecca C., et al. "Behavioral Weight Loss for the Management of Menopausal Hot Flashes: a Pilot Study." Menopause (New York, N.Y.), vol. 22, no. 1, 2015, pp. 59-65.
Thurston RC, Ewing LJ, Low CA, et al. Behavioral weight loss for the management of menopausal hot flashes: a pilot study. Menopause. 2015;22(1):59-65.
Thurston, R. C., Ewing, L. J., Low, C. A., Christie, A. J., & Levine, M. D. (2015). Behavioral weight loss for the management of menopausal hot flashes: a pilot study. Menopause (New York, N.Y.), 22(1), 59-65. https://doi.org/10.1097/GME.0000000000000274
Thurston RC, et al. Behavioral Weight Loss for the Management of Menopausal Hot Flashes: a Pilot Study. Menopause. 2015;22(1):59-65. PubMed PMID: 24977456.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Behavioral weight loss for the management of menopausal hot flashes: a pilot study. AU - Thurston,Rebecca C, AU - Ewing,Linda J, AU - Low,Carissa A, AU - Christie,Aimee J, AU - Levine,Michele D, PY - 2014/7/1/entrez PY - 2014/7/1/pubmed PY - 2015/8/19/medline SP - 59 EP - 65 JF - Menopause (New York, N.Y.) JO - Menopause VL - 22 IS - 1 N2 - OBJECTIVE: Although adiposity has been considered to be protective against hot flashes, newer data suggest positive relationships between hot flashes and adiposity. No studies have been specifically designed to test whether weight loss reduces hot flashes. This pilot study aimed to evaluate the feasibility, acceptability, and initial efficacy of behavioral weight loss in reducing hot flashes. METHODS: Forty overweight or obese women with hot flashes (≥ 4 hot flashes/d) were randomized to either behavioral weight loss intervention or wait-list control. Hot flashes were assessed before and after intervention via physiologic monitoring, diary, and questionnaire. Comparisons of changes in hot flashes and anthropometrics between conditions were performed via Wilcoxon tests. RESULTS: Study retention (83%) and intervention satisfaction (93.8%) were high. Most women (74.1%) reported that hot flash reduction was a major motivator for losing weight. Women randomized to the weight loss intervention lost more weight (-8.86 kg) than did women randomized to control (+0.23 kg; P < 0.0001). Women randomized to weight loss also showed greater reductions in questionnaire-reported hot flashes (2-wk hot flashes, -63.0) than did women in the control group (-28.0; P = 0.03)-a difference not demonstrated in other hot flash measures. Reductions in weight and hot flashes were significantly correlated (eg, r = 0.47, P = 0.006). CONCLUSIONS: This pilot study shows a behavioral weight loss program that is feasible, acceptable, and effective in producing weight loss among overweight or obese women with hot flashes. Findings indicate the importance of a larger study designed to test behavioral weight loss for hot flash reduction. Hot flash management could motivate women to engage in this health-promoting behavior. SN - 1530-0374 UR - https://www.unboundmedicine.com/medline/citation/24977456/Behavioral_weight_loss_for_the_management_of_menopausal_hot_flashes:_a_pilot_study_ L2 - https://doi.org/10.1097/GME.0000000000000274 DB - PRIME DP - Unbound Medicine ER -