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Differential classical conditioning selectively heightens response gain of neural population activity in human visual cortex.
Psychophysiology. 2014 Nov; 51(11):1185-94.P

Abstract

Neutral cues, after being reliably paired with noxious events, prompt defensive engagement and amplified sensory responses. To examine the neurophysiology underlying these adaptive changes, we quantified the contrast-response function of visual cortical population activity during differential aversive conditioning. Steady-state visual evoked potentials (ssVEPs) were recorded while participants discriminated the orientation of rapidly flickering grating stimuli. During each trial, luminance contrast of the gratings was slowly increased and then decreased. Right-tilted gratings (CS+) were paired with loud white noise but left-tilted gratings (CS-) were not. The contrast-following waveform envelope of ssVEPs showed selective amplification of the CS+ only during the high-contrast stage of the viewing epoch. Findings support the notion that motivational relevance, learned in a time frame of minutes, affects vision through a response gain mechanism.

Links

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Authors+Show Affiliations

Song I
Center for the Study of Emotion and Attention, University of Florida, Gainesville, Florida, USA.
Keil A
No affiliation info available

MeSH

AdultConditioning, ClassicalElectroencephalographyEvoked Potentials, VisualFearFemaleHumansMalePattern Recognition, VisualVisual CortexYoung Adult

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24981277

Citation

Song, Inkyung, and Andreas Keil. "Differential Classical Conditioning Selectively Heightens Response Gain of Neural Population Activity in Human Visual Cortex." Psychophysiology, vol. 51, no. 11, 2014, pp. 1185-94.
Song I, Keil A. Differential classical conditioning selectively heightens response gain of neural population activity in human visual cortex. Psychophysiology. 2014;51(11):1185-94.
Song, I., & Keil, A. (2014). Differential classical conditioning selectively heightens response gain of neural population activity in human visual cortex. Psychophysiology, 51(11), 1185-94. https://doi.org/10.1111/psyp.12260
Song I, Keil A. Differential Classical Conditioning Selectively Heightens Response Gain of Neural Population Activity in Human Visual Cortex. Psychophysiology. 2014;51(11):1185-94. PubMed PMID: 24981277.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Differential classical conditioning selectively heightens response gain of neural population activity in human visual cortex. AU - Song,Inkyung, AU - Keil,Andreas, Y1 - 2014/07/01/ PY - 2014/01/14/received PY - 2014/05/13/accepted PY - 2014/7/2/entrez PY - 2014/7/2/pubmed PY - 2015/12/31/medline KW - Contrast KW - Differential fear conditioning KW - Response gain KW - Steady-state SP - 1185 EP - 94 JF - Psychophysiology JO - Psychophysiology VL - 51 IS - 11 N2 - Neutral cues, after being reliably paired with noxious events, prompt defensive engagement and amplified sensory responses. To examine the neurophysiology underlying these adaptive changes, we quantified the contrast-response function of visual cortical population activity during differential aversive conditioning. Steady-state visual evoked potentials (ssVEPs) were recorded while participants discriminated the orientation of rapidly flickering grating stimuli. During each trial, luminance contrast of the gratings was slowly increased and then decreased. Right-tilted gratings (CS+) were paired with loud white noise but left-tilted gratings (CS-) were not. The contrast-following waveform envelope of ssVEPs showed selective amplification of the CS+ only during the high-contrast stage of the viewing epoch. Findings support the notion that motivational relevance, learned in a time frame of minutes, affects vision through a response gain mechanism. SN - 1540-5958 UR - https://www.unboundmedicine.com/medline/citation/24981277/Differential_classical_conditioning_selectively_heightens_response_gain_of_neural_population_activity_in_human_visual_cortex_ DB - PRIME DP - Unbound Medicine ER -