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Relation of mean platelet volume with obstructive adenoid hypertrophy in children.
Int J Pediatr Otorhinolaryngol 2014; 78(9):1449-51IJ

Abstract

OBJECTIVE

Adenoid hypertrophy (AH) is a common etiology of chronic upper airway obstruction. Upper respiratory tract obstruction may cause chronic alveolar hypoventilation and pulmonary vasoconstriction. In one previous study in patients with obstructive sleep apnea (OSA), it has been claimed that mean platelet volume (MPV), an indicator of platelet activation is increased and that MPV has an important role in the pathophysiology of cardiovascular diseases. We investigated in our study if MPV can be used as an indicator of obstruction due to adenoid hypertrophy.

METHODS

Our study includes 61 children that underwent adenoidectomy with a mean age of 7.12 (± 2.373). White blood cell, platelet count, MPV, platelet crit and platelet distribution width levels were measured before and 3 months after adenoidectomy. Children's symptoms for upper airway obstruction (UAO) (presence of snoring, mouth breathing or difficulty in breathing during sleep, obstructive breathing or apnea during sleep) were questioned in the preoperative and postoperative period by a standardized questionnaire.

RESULTS

There was no significant difference between preoperative and postoperative mean values of MPV, hemoglobin, platelet count (p > 0.05). White blood cell levels were significantly higher in the preoperative period values compared with postoperative period values (p < 0.05). Preoperative UAO scores were significantly higher than the postoperative UAO scores. After stratification of the degree of obstruction (as mild, moderate and severe) there was no significant difference in between groups in terms of MPV values.

CONCLUSION

There was no significant relation between MPV levels and obstructive adenoid hypertrophy.

Authors+Show Affiliations

Umraniye Research and Education Hospital, Department of Otolaryngology, Istanbul, Turkey. Electronic address: serap_sahin1985@hotmail.com.Umraniye Research and Education Hospital, Department of Otolaryngology, Istanbul, Turkey.Umraniye Research and Education Hospital, Department of Otolaryngology, Istanbul, Turkey.Umraniye Research and Education Hospital, Department of Otolaryngology, Istanbul, Turkey.Umraniye Research and Education Hospital, Department of Otolaryngology, Istanbul, Turkey.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

24997690

Citation

Onder, Serap, et al. "Relation of Mean Platelet Volume With Obstructive Adenoid Hypertrophy in Children." International Journal of Pediatric Otorhinolaryngology, vol. 78, no. 9, 2014, pp. 1449-51.
Onder S, Caypinar B, Sahin-Yilmaz A, et al. Relation of mean platelet volume with obstructive adenoid hypertrophy in children. Int J Pediatr Otorhinolaryngol. 2014;78(9):1449-51.
Onder, S., Caypinar, B., Sahin-Yilmaz, A., Toros, S. Z., & Oysu, C. (2014). Relation of mean platelet volume with obstructive adenoid hypertrophy in children. International Journal of Pediatric Otorhinolaryngology, 78(9), pp. 1449-51. doi:10.1016/j.ijporl.2014.06.001.
Onder S, et al. Relation of Mean Platelet Volume With Obstructive Adenoid Hypertrophy in Children. Int J Pediatr Otorhinolaryngol. 2014;78(9):1449-51. PubMed PMID: 24997690.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Relation of mean platelet volume with obstructive adenoid hypertrophy in children. AU - Onder,Serap, AU - Caypinar,Basak, AU - Sahin-Yilmaz,Asli, AU - Toros,Sema Zer, AU - Oysu,Cagatay, Y1 - 2014/06/16/ PY - 2014/01/10/received PY - 2014/06/03/revised PY - 2014/06/05/accepted PY - 2014/7/7/entrez PY - 2014/7/7/pubmed PY - 2015/5/13/medline KW - Adenoid hypertrophy KW - Adenoidectomy KW - Mean platelet volume KW - Pediatric obstructive sleep apnea SP - 1449 EP - 51 JF - International journal of pediatric otorhinolaryngology JO - Int. J. Pediatr. Otorhinolaryngol. VL - 78 IS - 9 N2 - OBJECTIVE: Adenoid hypertrophy (AH) is a common etiology of chronic upper airway obstruction. Upper respiratory tract obstruction may cause chronic alveolar hypoventilation and pulmonary vasoconstriction. In one previous study in patients with obstructive sleep apnea (OSA), it has been claimed that mean platelet volume (MPV), an indicator of platelet activation is increased and that MPV has an important role in the pathophysiology of cardiovascular diseases. We investigated in our study if MPV can be used as an indicator of obstruction due to adenoid hypertrophy. METHODS: Our study includes 61 children that underwent adenoidectomy with a mean age of 7.12 (± 2.373). White blood cell, platelet count, MPV, platelet crit and platelet distribution width levels were measured before and 3 months after adenoidectomy. Children's symptoms for upper airway obstruction (UAO) (presence of snoring, mouth breathing or difficulty in breathing during sleep, obstructive breathing or apnea during sleep) were questioned in the preoperative and postoperative period by a standardized questionnaire. RESULTS: There was no significant difference between preoperative and postoperative mean values of MPV, hemoglobin, platelet count (p > 0.05). White blood cell levels were significantly higher in the preoperative period values compared with postoperative period values (p < 0.05). Preoperative UAO scores were significantly higher than the postoperative UAO scores. After stratification of the degree of obstruction (as mild, moderate and severe) there was no significant difference in between groups in terms of MPV values. CONCLUSION: There was no significant relation between MPV levels and obstructive adenoid hypertrophy. SN - 1872-8464 UR - https://www.unboundmedicine.com/medline/citation/24997690/Relation_of_mean_platelet_volume_with_obstructive_adenoid_hypertrophy_in_children_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0165-5876(14)00329-2 DB - PRIME DP - Unbound Medicine ER -