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Association Between Contrast Media Volume-Glomerular Filtration Rate Ratio and Contrast-Induced Acute Kidney Injury After Primary Percutaneous Coronary Intervention.
Angiology. 2015 Jul; 66(6):519-24.A

Abstract

We hypothesized that contrast media volume-estimated glomerular filtration rate (CV-e-GFR) ratio may be a predictor of contrast media-induced acute kidney injury (CI-AKI). We investigated the associations between CV-e-GFR ratio and CI-AKI in 597 patients undergoing primary percutaneous coronary intervention (pPCI). An absolute ≥0.3 mg/dL increase in serum creatinine compared with baseline levels within 48 hours after the procedure was considered as CI-AKI; 78 (13.1%) of the 597 patients experienced CI-AKI. The amount of contrast during procedure was higher in the CI-AKI group than in those without CI-AKI (153 vs 135 mL, P = .003). The CV-e-GFR ratio was significantly higher in patients with CI-AKI than without (2.3 vs 1.5, P < .001). In multivariate analysis, independent predictors of CI-AKI were low left ventricular ejection fraction (P = .018, odds ratio [OR] = 0.966), e-GFR <60 mL/min (P = .012, OR = 2.558), and CV-e-GFR >2 (P < .001, OR = 5.917). In conclusion, CV-e-GFR ratio is significantly associated with CI-AKI after pPCI.

Authors+Show Affiliations

Department of Cardiology, Mehmet Akif Ersoy Chest and Cardiovascular Surgery Education and Research Hospital, Istanbul, Turkey dromer383434@gmail.com.Department of Cardiology, Mehmet Akif Ersoy Chest and Cardiovascular Surgery Education and Research Hospital, Istanbul, Turkey.Department of Cardiology, Muğla Sitki Kocman University School of Medicine, Muğla, Turkey.Department of Cardiology, Bağcilar Education and Research Hospital, Istanbul, Turkey.Department of Cardiology, Mehmet Akif Ersoy Chest and Cardiovascular Surgery Education and Research Hospital, Istanbul, Turkey.Department of Cardiology, Mehmet Akif Ersoy Chest and Cardiovascular Surgery Education and Research Hospital, Istanbul, Turkey.Department of Cardiology, Mehmet Akif Ersoy Chest and Cardiovascular Surgery Education and Research Hospital, Istanbul, Turkey.Department of Cardiology, Mehmet Akif Ersoy Chest and Cardiovascular Surgery Education and Research Hospital, Istanbul, Turkey.Department of Cardiology, Mehmet Akif Ersoy Chest and Cardiovascular Surgery Education and Research Hospital, Istanbul, Turkey.Department of Cardiology, Mehmet Akif Ersoy Chest and Cardiovascular Surgery Education and Research Hospital, Istanbul, Turkey.Department of Cardiology, Mehmet Akif Ersoy Chest and Cardiovascular Surgery Education and Research Hospital, Istanbul, Turkey.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

25005762

Citation

Celik, Omer, et al. "Association Between Contrast Media Volume-Glomerular Filtration Rate Ratio and Contrast-Induced Acute Kidney Injury After Primary Percutaneous Coronary Intervention." Angiology, vol. 66, no. 6, 2015, pp. 519-24.
Celik O, Ozturk D, Akin F, et al. Association Between Contrast Media Volume-Glomerular Filtration Rate Ratio and Contrast-Induced Acute Kidney Injury After Primary Percutaneous Coronary Intervention. Angiology. 2015;66(6):519-24.
Celik, O., Ozturk, D., Akin, F., Ayca, B., Yalcın, A. A., Erturk, M., Bıyık, I., Ayaz, A., Akturk, I. F., Enhos, A., & Aslan, S. (2015). Association Between Contrast Media Volume-Glomerular Filtration Rate Ratio and Contrast-Induced Acute Kidney Injury After Primary Percutaneous Coronary Intervention. Angiology, 66(6), 519-24. https://doi.org/10.1177/0003319714542277
Celik O, et al. Association Between Contrast Media Volume-Glomerular Filtration Rate Ratio and Contrast-Induced Acute Kidney Injury After Primary Percutaneous Coronary Intervention. Angiology. 2015;66(6):519-24. PubMed PMID: 25005762.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Association Between Contrast Media Volume-Glomerular Filtration Rate Ratio and Contrast-Induced Acute Kidney Injury After Primary Percutaneous Coronary Intervention. AU - Celik,Omer, AU - Ozturk,Derya, AU - Akin,Fatih, AU - Ayca,Burak, AU - Yalcın,Ahmet Arif, AU - Erturk,Mehmet, AU - Bıyık,Ismail, AU - Ayaz,Ahmet, AU - Akturk,Ibrahim Faruk, AU - Enhos,Asım, AU - Aslan,Serkan, Y1 - 2014/07/08/ PY - 2014/7/10/entrez PY - 2014/7/10/pubmed PY - 2015/8/25/medline KW - contrast media volume–estimated glomerular filtration ratio KW - contrast-induced acute kidney injury KW - primary percutaneous coronary intervention SP - 519 EP - 24 JF - Angiology JO - Angiology VL - 66 IS - 6 N2 - We hypothesized that contrast media volume-estimated glomerular filtration rate (CV-e-GFR) ratio may be a predictor of contrast media-induced acute kidney injury (CI-AKI). We investigated the associations between CV-e-GFR ratio and CI-AKI in 597 patients undergoing primary percutaneous coronary intervention (pPCI). An absolute ≥0.3 mg/dL increase in serum creatinine compared with baseline levels within 48 hours after the procedure was considered as CI-AKI; 78 (13.1%) of the 597 patients experienced CI-AKI. The amount of contrast during procedure was higher in the CI-AKI group than in those without CI-AKI (153 vs 135 mL, P = .003). The CV-e-GFR ratio was significantly higher in patients with CI-AKI than without (2.3 vs 1.5, P < .001). In multivariate analysis, independent predictors of CI-AKI were low left ventricular ejection fraction (P = .018, odds ratio [OR] = 0.966), e-GFR <60 mL/min (P = .012, OR = 2.558), and CV-e-GFR >2 (P < .001, OR = 5.917). In conclusion, CV-e-GFR ratio is significantly associated with CI-AKI after pPCI. SN - 1940-1574 UR - https://www.unboundmedicine.com/medline/citation/25005762/Association_Between_Contrast_Media_Volume_Glomerular_Filtration_Rate_Ratio_and_Contrast_Induced_Acute_Kidney_Injury_After_Primary_Percutaneous_Coronary_Intervention_ L2 - http://journals.sagepub.com/doi/full/10.1177/0003319714542277?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -