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Massive systemic amyloidosis associated with light-chain deposition disease.
Nephron. 1989; 52(2):139-43.N

Abstract

A 72-year-old woman presented with rapidly progressive renal failure and multiple myeloma. The patient died 6 months later of severe hepatic insufficiency. The light-microscopic, immunological and ultrastructural findings showed widespread kappa-light-chain deposits including the kidneys, liver, spleen, heart, lungs, tongue, ovary, pancreas and bone marrow associated with massive AL amyloid deposits in the same organs and in the thyroid gland. The concurrent presence of two different deposits is very unusual and the possible mechanisms for such an association are discussed.

Authors+Show Affiliations

Department of Haematology, CHU Clemenceau, Caen, France.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

2500613

Citation

Troussard, X, et al. "Massive Systemic Amyloidosis Associated With Light-chain Deposition Disease." Nephron, vol. 52, no. 2, 1989, pp. 139-43.
Troussard X, Hurault de Ligny B, Gallet B, et al. Massive systemic amyloidosis associated with light-chain deposition disease. Nephron. 1989;52(2):139-43.
Troussard, X., Hurault de Ligny, B., Gallet, B., Ganeval, D., Mandard, J. C., Ryckelynck, J. P., & Leporrier, M. (1989). Massive systemic amyloidosis associated with light-chain deposition disease. Nephron, 52(2), 139-43.
Troussard X, et al. Massive Systemic Amyloidosis Associated With Light-chain Deposition Disease. Nephron. 1989;52(2):139-43. PubMed PMID: 2500613.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Massive systemic amyloidosis associated with light-chain deposition disease. AU - Troussard,X, AU - Hurault de Ligny,B, AU - Gallet,B, AU - Ganeval,D, AU - Mandard,J C, AU - Ryckelynck,J P, AU - Leporrier,M, PY - 1989/1/1/pubmed PY - 1989/1/1/medline PY - 1989/1/1/entrez SP - 139 EP - 43 JF - Nephron JO - Nephron VL - 52 IS - 2 N2 - A 72-year-old woman presented with rapidly progressive renal failure and multiple myeloma. The patient died 6 months later of severe hepatic insufficiency. The light-microscopic, immunological and ultrastructural findings showed widespread kappa-light-chain deposits including the kidneys, liver, spleen, heart, lungs, tongue, ovary, pancreas and bone marrow associated with massive AL amyloid deposits in the same organs and in the thyroid gland. The concurrent presence of two different deposits is very unusual and the possible mechanisms for such an association are discussed. SN - 1660-8151 UR - https://www.unboundmedicine.com/medline/citation/2500613/Massive_systemic_amyloidosis_associated_with_light_chain_deposition_disease_ L2 - http://www.diseaseinfosearch.org/result/380 DB - PRIME DP - Unbound Medicine ER -