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Management of refractory OAB in the non-neurogenic patient.
Curr Urol Rep. 2014 Sep; 15(9):438.CU

Abstract

Overactive bladder (OAB) is one of the most common bothersome urological diseases. It also has a negative economic impact. Pathophysiology entails changes in neurogenic and myogenic factors, as well as urinary biomarkers such as nerve growth factor (NGF) and prostaglandins (PGs). With symptoms from OAB-Dry to OAB-Wet, the urodynamic pattern of OAB bladder is often characterized by idiopathic detrusor overactivity with lower threshold of sensation, diminished compliance and capacity. Treatment ranges from a combination of behavioral modifications (BM)/ pelvic floor muscle training (PFMT) to combinations of antimuscarinics, Botox injection, nerve stimulation and augmentation cystoplasty. Herein, a contemporary review on the different aspects of management of refractory OAB in patients without neuropathic disorders is presented.

Authors+Show Affiliations

Voiding Dysfunction and Female Urology, Urology& Nephrology Center, Mansoura University, Mansoura, Egypt, bassem_wadie@mans.edu.eg.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

25015301

Citation

Wadie, Bassem S.. "Management of Refractory OAB in the Non-neurogenic Patient." Current Urology Reports, vol. 15, no. 9, 2014, p. 438.
Wadie BS. Management of refractory OAB in the non-neurogenic patient. Curr Urol Rep. 2014;15(9):438.
Wadie, B. S. (2014). Management of refractory OAB in the non-neurogenic patient. Current Urology Reports, 15(9), 438. https://doi.org/10.1007/s11934-014-0438-x
Wadie BS. Management of Refractory OAB in the Non-neurogenic Patient. Curr Urol Rep. 2014;15(9):438. PubMed PMID: 25015301.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Management of refractory OAB in the non-neurogenic patient. A1 - Wadie,Bassem S, PY - 2014/7/13/entrez PY - 2014/7/13/pubmed PY - 2015/3/31/medline SP - 438 EP - 438 JF - Current urology reports JO - Curr Urol Rep VL - 15 IS - 9 N2 - Overactive bladder (OAB) is one of the most common bothersome urological diseases. It also has a negative economic impact. Pathophysiology entails changes in neurogenic and myogenic factors, as well as urinary biomarkers such as nerve growth factor (NGF) and prostaglandins (PGs). With symptoms from OAB-Dry to OAB-Wet, the urodynamic pattern of OAB bladder is often characterized by idiopathic detrusor overactivity with lower threshold of sensation, diminished compliance and capacity. Treatment ranges from a combination of behavioral modifications (BM)/ pelvic floor muscle training (PFMT) to combinations of antimuscarinics, Botox injection, nerve stimulation and augmentation cystoplasty. Herein, a contemporary review on the different aspects of management of refractory OAB in patients without neuropathic disorders is presented. SN - 1534-6285 UR - https://www.unboundmedicine.com/medline/citation/25015301/Management_of_refractory_OAB_in_the_non_neurogenic_patient_ L2 - https://dx.doi.org/10.1007/s11934-014-0438-x DB - PRIME DP - Unbound Medicine ER -