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Malignant lues in an immunocompetent patient.
Int J STD AIDS. 2015 Jun; 26(7):518-20.IJ

Abstract

Malignant lues is a rare form of secondary syphilis mostly associated with HIV infection. It is an uncommon presentation of syphilis even rarer in immunocompetent patients. We present the case of a 57-year-old homosexual man referred to our department due to a 4-month history of a disseminated, slightly painful, nodular-ulcerative cutaneous eruption associated with low-grade fever, malaise and aesthenia. Regarding the clinical features and serological and histopathological findings, the diagnosis of syphilis maligna was assumed. Serology for HIV was repeatedly negative. This case is interesting, not only because a very uncommon form of secondary syphilis was identified but also for being diagnosed in an immunocompetent patient. Lack of awareness of this type of presentation delays the diagnosis and treatment, leading to an increase in morbidity and spread of infection.

Authors+Show Affiliations

Department of Dermatology and Venereology, Garcia de Orta Hospital, Almada, Portugal alves.joaovitor@gmail.com.Department of Dermatology and Venereology, Garcia de Orta Hospital, Almada, Portugal.Department of Dermatology and Venereology, Garcia de Orta Hospital, Almada, Portugal.Department of Dermatology and Venereology, Garcia de Orta Hospital, Almada, Portugal.Department of Dermatology and Venereology, Garcia de Orta Hospital, Almada, Portugal.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

25015934

Citation

Alves, João, et al. "Malignant Lues in an Immunocompetent Patient." International Journal of STD & AIDS, vol. 26, no. 7, 2015, pp. 518-20.
Alves J, António AM, Matos D, et al. Malignant lues in an immunocompetent patient. Int J STD AIDS. 2015;26(7):518-20.
Alves, J., António, A. M., Matos, D., Coelho, R., & Cachão, P. (2015). Malignant lues in an immunocompetent patient. International Journal of STD & AIDS, 26(7), 518-20. https://doi.org/10.1177/0956462414544162
Alves J, et al. Malignant Lues in an Immunocompetent Patient. Int J STD AIDS. 2015;26(7):518-20. PubMed PMID: 25015934.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Malignant lues in an immunocompetent patient. AU - Alves,João, AU - António,Ana Marta, AU - Matos,Diogo, AU - Coelho,Ricardo, AU - Cachão,Pedro, Y1 - 2014/07/11/ PY - 2014/05/18/received PY - 2014/06/23/accepted PY - 2014/7/13/entrez PY - 2014/7/13/pubmed PY - 2015/10/22/medline KW - AIDS KW - HIV KW - Syphilis (Treponema pallidum) KW - bacterial disease KW - lues maligna KW - malignant syphilis KW - sexually transmitted infection SP - 518 EP - 20 JF - International journal of STD & AIDS JO - Int J STD AIDS VL - 26 IS - 7 N2 - Malignant lues is a rare form of secondary syphilis mostly associated with HIV infection. It is an uncommon presentation of syphilis even rarer in immunocompetent patients. We present the case of a 57-year-old homosexual man referred to our department due to a 4-month history of a disseminated, slightly painful, nodular-ulcerative cutaneous eruption associated with low-grade fever, malaise and aesthenia. Regarding the clinical features and serological and histopathological findings, the diagnosis of syphilis maligna was assumed. Serology for HIV was repeatedly negative. This case is interesting, not only because a very uncommon form of secondary syphilis was identified but also for being diagnosed in an immunocompetent patient. Lack of awareness of this type of presentation delays the diagnosis and treatment, leading to an increase in morbidity and spread of infection. SN - 1758-1052 UR - https://www.unboundmedicine.com/medline/citation/25015934/Malignant_lues_in_an_immunocompetent_patient_ L2 - http://journals.sagepub.com/doi/full/10.1177/0956462414544162?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -