Tags

Type your tag names separated by a space and hit enter

Gender differences in the relationship between plasma lipids and fasting plasma glucose in non-diabetic urban Chinese population: a cross-section study.
Front Med. 2014 Dec; 8(4):477-83.FM

Abstract

The association between dyslipidemia and elevated fasting glucose in type 2 diabetes is well known. In non-diabetes, whether this association still exists, and whether dyslipidemia is an independent risk factor for high fasting plasma glucose (FPG) levels are not clear. This cross-sectional study recruited 3460 non-diabetic Chinese subjects (1027 men, and 2433 women, aged 35-75 years old) who participated in a health survey. Men and women were classified into tertiles by levels of plasma lipids respectively. In women, the prevalence of impaired fasting glucose (IFG) was decreased with increased HDL-C. A stepwise increase in HDL-C was associated with decreasing FPG levels (lowest tertiles, FPG: 5.376 ± 0.018; middle tertiles, 5.324 ± 0.018; highest tertiles, 5.276 ± 0.018 mmol/L; P = 0.001). Reversely, FPG levels increased from lowest tertiles to highest tertiles of LDL-C, TC, and TG. we found that women in the first tertile with lower HDL-C level had a 1.75-fold increase in risk of IFG compared with non-diabetic women in the third tertile with higher HDL-C level (OR: 1.75; 95% CI: 1.20-2.56). In men, no significant association was found. We took age, BMI, waist/hip ratio, education, smoking, alcohol drinking, and physical exercise as adjusted variables. In Chinese non-diabetic women, dyslipidemia is independently associated with high levels of FPG; TG, HDL-C, and LDL-C are predictors of IFG independent of BMI and waist/hip ratio.

Authors+Show Affiliations

School of Nursing, Shanxi Medical University, Taiyuan, 030001, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

25034241

Citation

Zheng, Jie, et al. "Gender Differences in the Relationship Between Plasma Lipids and Fasting Plasma Glucose in Non-diabetic Urban Chinese Population: a Cross-section Study." Frontiers of Medicine, vol. 8, no. 4, 2014, pp. 477-83.
Zheng J, Gao Y, Jing Y, et al. Gender differences in the relationship between plasma lipids and fasting plasma glucose in non-diabetic urban Chinese population: a cross-section study. Front Med. 2014;8(4):477-83.
Zheng, J., Gao, Y., Jing, Y., Zhou, X., Shi, Y., Li, Y., Wang, L., Wang, R., Li, M., Xiao, C., Li, Y., & Li, R. (2014). Gender differences in the relationship between plasma lipids and fasting plasma glucose in non-diabetic urban Chinese population: a cross-section study. Frontiers of Medicine, 8(4), 477-83. https://doi.org/10.1007/s11684-014-0346-y
Zheng J, et al. Gender Differences in the Relationship Between Plasma Lipids and Fasting Plasma Glucose in Non-diabetic Urban Chinese Population: a Cross-section Study. Front Med. 2014;8(4):477-83. PubMed PMID: 25034241.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Gender differences in the relationship between plasma lipids and fasting plasma glucose in non-diabetic urban Chinese population: a cross-section study. AU - Zheng,Jie, AU - Gao,Yuzhen, AU - Jing,Yuejuan, AU - Zhou,Xiaoshuang, AU - Shi,Yuanyuan, AU - Li,Yanhong, AU - Wang,Lihua, AU - Wang,Ruiying, AU - Li,Maolian, AU - Xiao,Chuanshi, AU - Li,Yafeng, AU - Li,Rongshan, Y1 - 2014/07/17/ PY - 2013/09/13/received PY - 2014/06/12/accepted PY - 2014/7/19/entrez PY - 2014/7/19/pubmed PY - 2015/9/22/medline SP - 477 EP - 83 JF - Frontiers of medicine JO - Front Med VL - 8 IS - 4 N2 - The association between dyslipidemia and elevated fasting glucose in type 2 diabetes is well known. In non-diabetes, whether this association still exists, and whether dyslipidemia is an independent risk factor for high fasting plasma glucose (FPG) levels are not clear. This cross-sectional study recruited 3460 non-diabetic Chinese subjects (1027 men, and 2433 women, aged 35-75 years old) who participated in a health survey. Men and women were classified into tertiles by levels of plasma lipids respectively. In women, the prevalence of impaired fasting glucose (IFG) was decreased with increased HDL-C. A stepwise increase in HDL-C was associated with decreasing FPG levels (lowest tertiles, FPG: 5.376 ± 0.018; middle tertiles, 5.324 ± 0.018; highest tertiles, 5.276 ± 0.018 mmol/L; P = 0.001). Reversely, FPG levels increased from lowest tertiles to highest tertiles of LDL-C, TC, and TG. we found that women in the first tertile with lower HDL-C level had a 1.75-fold increase in risk of IFG compared with non-diabetic women in the third tertile with higher HDL-C level (OR: 1.75; 95% CI: 1.20-2.56). In men, no significant association was found. We took age, BMI, waist/hip ratio, education, smoking, alcohol drinking, and physical exercise as adjusted variables. In Chinese non-diabetic women, dyslipidemia is independently associated with high levels of FPG; TG, HDL-C, and LDL-C are predictors of IFG independent of BMI and waist/hip ratio. SN - 2095-0225 UR - https://www.unboundmedicine.com/medline/citation/25034241/Gender_differences_in_the_relationship_between_plasma_lipids_and_fasting_plasma_glucose_in_non_diabetic_urban_Chinese_population:_a_cross_section_study_ L2 - https://dx.doi.org/10.1007/s11684-014-0346-y DB - PRIME DP - Unbound Medicine ER -