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Dietary fiber intake and risk of renal cell carcinoma: evidence from a meta-analysis.
Med Oncol 2014; 31(8):125MO

Abstract

The aim of this study was to investigate the possible relationships between dietary fiber intake and risk of renal cell carcinoma (RCC). Electronic databases including MEDLINE, EMBASE and Web of Science were searched to find eligible studies. Random-effects relative risk (RR) and its corresponding 95 % confidence interval (CI) were used. Besides, random-effects dose-response analyses were also performed to clarify the dose-response relations. Finally, publication bias was assessed by Egger's test and Begg's test. All p values were two tailed. Seven studies, including two cohort studies and five case-control studies, were eligible and included in this meta-analysis. Overall analysis in highest versus lowest level revealed that total dietary fiber intake was associated with reduced RCC risk (RR 0.84, 95 % CI 0.74-0.96). In addition, pooled estimated data showed that risk of RCC was significantly associated with vegetable and legume fiber intake (RR 0.70, RR 0.80, respectively), but not with fruit and cereal fiber intake (RR 0.92, RR 1.04, respectively). However, in dose-response analysis, no significant association was reported. Finally, no publication bias was detected by Egger's or Begg's test. The dietary fiber intake, especially vegetable and legume fiber, may be associated with reduced RCC risk. Considering the limitations of the included studies, more well-designed prospective studies will be needed to confirm our findings.

Authors+Show Affiliations

Department of Urology, Shanghai Tenth People's Hospital, Tongji University, 301 Yanchang Road, Shanghai, 200072, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Meta-Analysis

Language

eng

PubMed ID

25038944

Citation

Huang, Tian-bao, et al. "Dietary Fiber Intake and Risk of Renal Cell Carcinoma: Evidence From a Meta-analysis." Medical Oncology (Northwood, London, England), vol. 31, no. 8, 2014, p. 125.
Huang TB, Ding PP, Chen JF, et al. Dietary fiber intake and risk of renal cell carcinoma: evidence from a meta-analysis. Med Oncol. 2014;31(8):125.
Huang, T. B., Ding, P. P., Chen, J. F., Yan, Y., Zhang, L., Liu, H., ... Yao, X. D. (2014). Dietary fiber intake and risk of renal cell carcinoma: evidence from a meta-analysis. Medical Oncology (Northwood, London, England), 31(8), p. 125. doi:10.1007/s12032-014-0125-2.
Huang TB, et al. Dietary Fiber Intake and Risk of Renal Cell Carcinoma: Evidence From a Meta-analysis. Med Oncol. 2014;31(8):125. PubMed PMID: 25038944.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dietary fiber intake and risk of renal cell carcinoma: evidence from a meta-analysis. AU - Huang,Tian-bao, AU - Ding,Pei-pei, AU - Chen,Jian-feng, AU - Yan,Yang, AU - Zhang,Long, AU - Liu,Huan, AU - Liu,Peng-cheng, AU - Che,Jian-ping, AU - Zheng,Jun-hua, AU - Yao,Xu-dong, Y1 - 2014/07/20/ PY - 2014/06/16/received PY - 2014/07/05/accepted PY - 2014/7/21/entrez PY - 2014/7/21/pubmed PY - 2015/5/15/medline SP - 125 EP - 125 JF - Medical oncology (Northwood, London, England) JO - Med. Oncol. VL - 31 IS - 8 N2 - The aim of this study was to investigate the possible relationships between dietary fiber intake and risk of renal cell carcinoma (RCC). Electronic databases including MEDLINE, EMBASE and Web of Science were searched to find eligible studies. Random-effects relative risk (RR) and its corresponding 95 % confidence interval (CI) were used. Besides, random-effects dose-response analyses were also performed to clarify the dose-response relations. Finally, publication bias was assessed by Egger's test and Begg's test. All p values were two tailed. Seven studies, including two cohort studies and five case-control studies, were eligible and included in this meta-analysis. Overall analysis in highest versus lowest level revealed that total dietary fiber intake was associated with reduced RCC risk (RR 0.84, 95 % CI 0.74-0.96). In addition, pooled estimated data showed that risk of RCC was significantly associated with vegetable and legume fiber intake (RR 0.70, RR 0.80, respectively), but not with fruit and cereal fiber intake (RR 0.92, RR 1.04, respectively). However, in dose-response analysis, no significant association was reported. Finally, no publication bias was detected by Egger's or Begg's test. The dietary fiber intake, especially vegetable and legume fiber, may be associated with reduced RCC risk. Considering the limitations of the included studies, more well-designed prospective studies will be needed to confirm our findings. SN - 1559-131X UR - https://www.unboundmedicine.com/medline/citation/25038944/Dietary_fiber_intake_and_risk_of_renal_cell_carcinoma:_evidence_from_a_meta_analysis_ L2 - https://dx.doi.org/10.1007/s12032-014-0125-2 DB - PRIME DP - Unbound Medicine ER -