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The spectra, symptom profiles and overlap of Rome III functional gastrointestinal disorders in a tertiary center in South China.
J Dig Dis. 2014 Oct; 15(10):538-44.JD

Abstract

OBJECTIVE

Most previous studies exploring the overlap of functional gastrointestinal disorders (FGID) focus on the overlap between functional dyspepsia (FD) and irritable bowel syndrome (IBS). In this study, we aimed to explore the spectra, symptom profiles and overlap of all FGID using the validated Chinese version of the Rome III questionnaire.

METHODS

Consecutive newly diagnosed FGID patients who were admitted to the Outpatient Gastroenterology Clinic from 10 May to 10 September 2012 were recruited in the study. All the patients complained of gastrointestinal (GI) symptoms for at least 3 months with a symptom onset of at least 6 months before diagnosis after excluded organic diseases. Patients who met the inclusion criteria were asked to complete the scoring algorithm for the Rome III integrated questionnaire.

RESULTS

Among 350 eligible patients, 302 (86.3%) returned completed questionnaires. A total of six major domains including 17 disorders were diagnosed. The four most prevalent FGID were FD (54.6%), IBS (40.7%), unspecified functional bowel disorder (13.9%) and functional constipation (12.6%). The three most prevalent symptoms in FGID were abdominal pain (66.2%), loose stool (58.3%) and abdominal bloating/distension (56.3%). Of the 302 patients, 152 (50.3%) had one to five overlapping FGID. Only functional bloating had no overlap. Six patients had five overlapping FGID simultaneously. In all, 63 patients had overlapping FD and IBS.

CONCLUSIONS

This study provided the detailed spectra and symptom profiles for all FGID. Overlapping FGID are common in China.

Authors+Show Affiliations

Department of Gastroenterology and Hepatology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong Province, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

25102919

Citation

Xiong, Li Shou, et al. "The Spectra, Symptom Profiles and Overlap of Rome III Functional Gastrointestinal Disorders in a Tertiary Center in South China." Journal of Digestive Diseases, vol. 15, no. 10, 2014, pp. 538-44.
Xiong LS, Shi Q, Gong XR, et al. The spectra, symptom profiles and overlap of Rome III functional gastrointestinal disorders in a tertiary center in South China. J Dig Dis. 2014;15(10):538-44.
Xiong, L. S., Shi, Q., Gong, X. R., Cui, Y., & Chen, M. H. (2014). The spectra, symptom profiles and overlap of Rome III functional gastrointestinal disorders in a tertiary center in South China. Journal of Digestive Diseases, 15(10), 538-44. https://doi.org/10.1111/1751-2980.12178
Xiong LS, et al. The Spectra, Symptom Profiles and Overlap of Rome III Functional Gastrointestinal Disorders in a Tertiary Center in South China. J Dig Dis. 2014;15(10):538-44. PubMed PMID: 25102919.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The spectra, symptom profiles and overlap of Rome III functional gastrointestinal disorders in a tertiary center in South China. AU - Xiong,Li Shou, AU - Shi,Quan, AU - Gong,Xiao Rong, AU - Cui,Yi, AU - Chen,Min Hu, PY - 2014/8/9/entrez PY - 2014/8/12/pubmed PY - 2015/10/6/medline KW - China KW - epidemiology KW - functional dyspepsia KW - functional gastrointestinal disorders KW - irritable bowel syndrome KW - overlap SP - 538 EP - 44 JF - Journal of digestive diseases JO - J Dig Dis VL - 15 IS - 10 N2 - OBJECTIVE: Most previous studies exploring the overlap of functional gastrointestinal disorders (FGID) focus on the overlap between functional dyspepsia (FD) and irritable bowel syndrome (IBS). In this study, we aimed to explore the spectra, symptom profiles and overlap of all FGID using the validated Chinese version of the Rome III questionnaire. METHODS: Consecutive newly diagnosed FGID patients who were admitted to the Outpatient Gastroenterology Clinic from 10 May to 10 September 2012 were recruited in the study. All the patients complained of gastrointestinal (GI) symptoms for at least 3 months with a symptom onset of at least 6 months before diagnosis after excluded organic diseases. Patients who met the inclusion criteria were asked to complete the scoring algorithm for the Rome III integrated questionnaire. RESULTS: Among 350 eligible patients, 302 (86.3%) returned completed questionnaires. A total of six major domains including 17 disorders were diagnosed. The four most prevalent FGID were FD (54.6%), IBS (40.7%), unspecified functional bowel disorder (13.9%) and functional constipation (12.6%). The three most prevalent symptoms in FGID were abdominal pain (66.2%), loose stool (58.3%) and abdominal bloating/distension (56.3%). Of the 302 patients, 152 (50.3%) had one to five overlapping FGID. Only functional bloating had no overlap. Six patients had five overlapping FGID simultaneously. In all, 63 patients had overlapping FD and IBS. CONCLUSIONS: This study provided the detailed spectra and symptom profiles for all FGID. Overlapping FGID are common in China. SN - 1751-2980 UR - https://www.unboundmedicine.com/medline/citation/25102919/The_spectra_symptom_profiles_and_overlap_of_Rome_III_functional_gastrointestinal_disorders_in_a_tertiary_center_in_South_China_ L2 - https://doi.org/10.1111/1751-2980.12178 DB - PRIME DP - Unbound Medicine ER -