Tags

Type your tag names separated by a space and hit enter

Effects of scaling and root planing on clinical response and serum levels of adipocytokines in patients with obesity and chronic periodontitis.
J Periodontol. 2015 Jan; 86(1):53-61.JP

Abstract

BACKGROUND

Despite several investigations suggesting that obesity is a risk indicator for periodontitis, little is known about the effect of obesity on periodontal treatment response. The aim of this study is to evaluate the effects of scaling and root planing (SRP) on clinical parameters and circulating levels of leptin and adiponectin in patients with obesity with chronic periodontitis (CP).

METHODS

Twenty-four patients with obesity and CP and 24 patients without obesity with CP were submitted to SRP. Clinical parameters were assessed at baseline and 3 and 6 months after therapy. Serum levels of leptin and adiponectin were evaluated at all time points, using enzyme-linked immunosorbent assay.

RESULTS

SRP improved the clinical parameters of both groups at 3 and 6 months (P < 0.05). Nonetheless, the patients without obesity presented a lower mean probing depth (PD) at 6 months after therapy and a greater reduction in PD from baseline to 6 months in the full-mouth analysis (primary outcome variable) and in initially deep sites (P < 0.05). Leptin serum levels were higher in patients with obesity than in patients without obesity at all time points (P < 0.05). No changes in the serum levels of leptin and adiponectin were observed in groups with and without obesity after therapy (P > 0.05).

CONCLUSIONS

Patients with obesity and CP presented lower reductions in PD than patients without obesity with CP at 6 months after SRP. Furthermore, the treatment did not affect the circulating levels of leptin and adiponectin in any group.

Authors+Show Affiliations

Department of Periodontology, Dental Research Division, Guarulhos University, Guarulhos, São Paulo, São Paulo, Brazil.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

25119561

Citation

Gonçalves, Tiago Eduardo Dias, et al. "Effects of Scaling and Root Planing On Clinical Response and Serum Levels of Adipocytokines in Patients With Obesity and Chronic Periodontitis." Journal of Periodontology, vol. 86, no. 1, 2015, pp. 53-61.
Gonçalves TE, Feres M, Zimmermann GS, et al. Effects of scaling and root planing on clinical response and serum levels of adipocytokines in patients with obesity and chronic periodontitis. J Periodontol. 2015;86(1):53-61.
Gonçalves, T. E., Feres, M., Zimmermann, G. S., Faveri, M., Figueiredo, L. C., Braga, P. G., & Duarte, P. M. (2015). Effects of scaling and root planing on clinical response and serum levels of adipocytokines in patients with obesity and chronic periodontitis. Journal of Periodontology, 86(1), 53-61. https://doi.org/10.1902/jop.2014.140266
Gonçalves TE, et al. Effects of Scaling and Root Planing On Clinical Response and Serum Levels of Adipocytokines in Patients With Obesity and Chronic Periodontitis. J Periodontol. 2015;86(1):53-61. PubMed PMID: 25119561.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effects of scaling and root planing on clinical response and serum levels of adipocytokines in patients with obesity and chronic periodontitis. AU - Gonçalves,Tiago Eduardo Dias, AU - Feres,Magda, AU - Zimmermann,Glaucia Santos, AU - Faveri,Marcelo, AU - Figueiredo,Luciene Cristina, AU - Braga,Paloma Gralha, AU - Duarte,Poliana Mendes, PY - 2014/8/15/entrez PY - 2014/8/15/pubmed PY - 2016/3/24/medline KW - Adipokines KW - Leptin KW - adiponectin KW - chronic periodontitis KW - obesity KW - root planing SP - 53 EP - 61 JF - Journal of periodontology JO - J. Periodontol. VL - 86 IS - 1 N2 - BACKGROUND: Despite several investigations suggesting that obesity is a risk indicator for periodontitis, little is known about the effect of obesity on periodontal treatment response. The aim of this study is to evaluate the effects of scaling and root planing (SRP) on clinical parameters and circulating levels of leptin and adiponectin in patients with obesity with chronic periodontitis (CP). METHODS: Twenty-four patients with obesity and CP and 24 patients without obesity with CP were submitted to SRP. Clinical parameters were assessed at baseline and 3 and 6 months after therapy. Serum levels of leptin and adiponectin were evaluated at all time points, using enzyme-linked immunosorbent assay. RESULTS: SRP improved the clinical parameters of both groups at 3 and 6 months (P < 0.05). Nonetheless, the patients without obesity presented a lower mean probing depth (PD) at 6 months after therapy and a greater reduction in PD from baseline to 6 months in the full-mouth analysis (primary outcome variable) and in initially deep sites (P < 0.05). Leptin serum levels were higher in patients with obesity than in patients without obesity at all time points (P < 0.05). No changes in the serum levels of leptin and adiponectin were observed in groups with and without obesity after therapy (P > 0.05). CONCLUSIONS: Patients with obesity and CP presented lower reductions in PD than patients without obesity with CP at 6 months after SRP. Furthermore, the treatment did not affect the circulating levels of leptin and adiponectin in any group. SN - 1943-3670 UR - https://www.unboundmedicine.com/medline/citation/25119561/Effects_of_scaling_and_root_planing_on_clinical_response_and_serum_levels_of_adipocytokines_in_patients_with_obesity_and_chronic_periodontitis_ L2 - https://doi.org/10.1902/jop.2014.140266 DB - PRIME DP - Unbound Medicine ER -