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A rare pediatric case of cutaneous gamma/delta T-cell lymphoma.
Ann Biol Clin (Paris) 2014 Jul-Aug; 72(4):483-5AB

Abstract

Cutaneous γ/δ T-cell lymphoma (CGD-TCL) is a recent entity described in the newly revised World health organization-European organization for research and treatment of cancer classification of cutaneous lymphomas. Only a few cases have been reported, of which two pediatric cases. A 15 years old child with a 6 months history of polyadenopathy, cutaneous lesions, general edema and deterioration of general condition was hospitalized. Results from laboratory testing, cutaneous histopathology and immunohistochemistry showed a primary CGD-TCL. Staging was completed by a total body computed tomography. Therapy was planified with SMILE protocol. It is a highly aggressive tumor resistant to chemotherapy, immunotherapy, and radiation therapy. The GDTCL is characterized by a worse prognosis with a median survival of 15 months. Early diagnosis is essential and aggressive therapy is necessary.

Authors+Show Affiliations

Department of hematology Military Hospital Mohammed V, Rabat, Morocco, Department of internal medicine, Military Hospital Mohammed V, Rabat, Morocco.Department of internal medicine, Military Hospital Mohammed V, Rabat, Morocco.Department of internal medicine, Military Hospital Mohammed V, Rabat, Morocco.Department of internal medicine, Military Hospital Mohammed V, Rabat, Morocco.Department of internal medicine, Military Hospital Mohammed V, Rabat, Morocco.Department of internal medicine, Military Hospital Mohammed V, Rabat, Morocco.Department of hematology Military Hospital Mohammed V, Rabat, Morocco.Department of internal medicine, Military Hospital Mohammed V, Rabat, Morocco.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

25119808

Citation

Kerbout, Malika, et al. "A Rare Pediatric Case of Cutaneous Gamma/delta T-cell Lymphoma." Annales De Biologie Clinique, vol. 72, no. 4, 2014, pp. 483-5.
Kerbout M, Mekouar F, Bahadi N, et al. A rare pediatric case of cutaneous gamma/delta T-cell lymphoma. Ann Biol Clin (Paris). 2014;72(4):483-5.
Kerbout, M., Mekouar, F., Bahadi, N., El Omri, N., Assoufi, N., El Qatni, M., ... Ghafir, D. (2014). A rare pediatric case of cutaneous gamma/delta T-cell lymphoma. Annales De Biologie Clinique, 72(4), pp. 483-5. doi:10.1684/abc.2014.0970.
Kerbout M, et al. A Rare Pediatric Case of Cutaneous Gamma/delta T-cell Lymphoma. Ann Biol Clin (Paris). 2014;72(4):483-5. PubMed PMID: 25119808.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A rare pediatric case of cutaneous gamma/delta T-cell lymphoma. AU - Kerbout,Malika, AU - Mekouar,Fedoua, AU - Bahadi,Nisrine, AU - El Omri,Nawal, AU - Assoufi,Nawfal, AU - El Qatni,Mohamed, AU - Mikdame,Mohamed, AU - Ghafir,Driss, PY - 2014/8/15/entrez PY - 2014/8/15/pubmed PY - 2015/10/31/medline KW - SMILE KW - WHO-EORTC classification KW - cutaneous γ/δ T-cell lymphoma KW - paediatric KW - primary cutaneous lymphoma SP - 483 EP - 5 JF - Annales de biologie clinique JO - Ann. Biol. Clin. (Paris) VL - 72 IS - 4 N2 - Cutaneous γ/δ T-cell lymphoma (CGD-TCL) is a recent entity described in the newly revised World health organization-European organization for research and treatment of cancer classification of cutaneous lymphomas. Only a few cases have been reported, of which two pediatric cases. A 15 years old child with a 6 months history of polyadenopathy, cutaneous lesions, general edema and deterioration of general condition was hospitalized. Results from laboratory testing, cutaneous histopathology and immunohistochemistry showed a primary CGD-TCL. Staging was completed by a total body computed tomography. Therapy was planified with SMILE protocol. It is a highly aggressive tumor resistant to chemotherapy, immunotherapy, and radiation therapy. The GDTCL is characterized by a worse prognosis with a median survival of 15 months. Early diagnosis is essential and aggressive therapy is necessary. SN - 1950-6112 UR - https://www.unboundmedicine.com/medline/citation/25119808/A_rare_pediatric_case_of_cutaneous_gamma/delta_T_cell_lymphoma_ L2 - http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/abc.2014.0970 DB - PRIME DP - Unbound Medicine ER -