Tags

Type your tag names separated by a space and hit enter

The variability of ecstasy tablets composition in Brazil.
J Forensic Sci. 2015 Jan; 60(1):147-51.JF

Abstract

The content of ecstasy tablets has been changing over the years, and nowadays 3,4-methylenedioxymethamphetamine (MDMA) is not always present in the tablets. The aim of this study was to investigate the chemical composition in the seized tablets labeled as ecstasy. We analyzed samples from 150 different seizures made by Sao Paulo's State Police by gas chromatography-mass spectrometry. MDMA was present in 44.7% of the analyzed samples, and another twenty different active substances were identified in these tablets, such as caffeine, 2C-B, piperazines, amphetamines, phencyclidine, and others. Methamphetamine was present in 22% of these samples. The results demonstrate a huge shift in the pattern of trafficking of synthetic drugs, where MDMA has been replaced in tablets mostly by illicit psychoactive substances, in a clear attempt to bypass the law. The great variability in the tablets composition may lead to an increased risk of drug poisoning.

Authors+Show Affiliations

Forensic Toxicology and Chemistry Laboratory, Criminalistic Institute of São Paulo, São Paulo, SP, 05507-060, Brazil.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

25125149

Citation

Togni, Loraine R., et al. "The Variability of Ecstasy Tablets Composition in Brazil." Journal of Forensic Sciences, vol. 60, no. 1, 2015, pp. 147-51.
Togni LR, Lanaro R, Resende RR, et al. The variability of ecstasy tablets composition in Brazil. J Forensic Sci. 2015;60(1):147-51.
Togni, L. R., Lanaro, R., Resende, R. R., & Costa, J. L. (2015). The variability of ecstasy tablets composition in Brazil. Journal of Forensic Sciences, 60(1), 147-51. https://doi.org/10.1111/1556-4029.12584
Togni LR, et al. The Variability of Ecstasy Tablets Composition in Brazil. J Forensic Sci. 2015;60(1):147-51. PubMed PMID: 25125149.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The variability of ecstasy tablets composition in Brazil. AU - Togni,Loraine R, AU - Lanaro,Rafael, AU - Resende,Rodrigo R, AU - Costa,Jose L, Y1 - 2014/08/14/ PY - 2013/02/23/received PY - 2013/11/26/revised PY - 2013/12/07/accepted PY - 2014/8/16/entrez PY - 2014/8/16/pubmed PY - 2015/11/17/medline KW - MDMA KW - chemical profiling KW - designer drugs KW - ecstasy KW - forensic science KW - gas chromatography-mass spectrometry SP - 147 EP - 51 JF - Journal of forensic sciences JO - J. Forensic Sci. VL - 60 IS - 1 N2 - The content of ecstasy tablets has been changing over the years, and nowadays 3,4-methylenedioxymethamphetamine (MDMA) is not always present in the tablets. The aim of this study was to investigate the chemical composition in the seized tablets labeled as ecstasy. We analyzed samples from 150 different seizures made by Sao Paulo's State Police by gas chromatography-mass spectrometry. MDMA was present in 44.7% of the analyzed samples, and another twenty different active substances were identified in these tablets, such as caffeine, 2C-B, piperazines, amphetamines, phencyclidine, and others. Methamphetamine was present in 22% of these samples. The results demonstrate a huge shift in the pattern of trafficking of synthetic drugs, where MDMA has been replaced in tablets mostly by illicit psychoactive substances, in a clear attempt to bypass the law. The great variability in the tablets composition may lead to an increased risk of drug poisoning. SN - 1556-4029 UR - https://www.unboundmedicine.com/medline/citation/25125149/The_variability_of_ecstasy_tablets_composition_in_Brazil_ L2 - https://doi.org/10.1111/1556-4029.12584 DB - PRIME DP - Unbound Medicine ER -