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Acantholytic dyskeratotic acanthoma: case report and review of the literature.
Dermatol Pract Concept. 2014 Jul; 4(3):25-30.DP

Abstract

BACKGROUND

Focal acantholytic dyskeratosis has been described as an incidental finding and as a clinically distinct lesion. In both situations, a dimorphic histologic pattern is observed: acantholysis and dyskeratosis. Solitary, non-genital lesions displaying such pathology have been difficult to classify. Clinical and pathological characteristics of acantholytic dyskeratotic acanthomas are described.

METHODS

The features of a patient with solitary, non-genital, acantholytic dyskeratotic acanthoma are presented and the literature on acantholytic dyskeratotic acanthomas is reviewed. Using PubMed the following terms were searched and relevant citations assessed: acantholysis, acanthoma, cutaneous, dyskeratosis, nail, warty.

RESULTS

We identified 30 cutaneous acantholytic dyskeratotic acanthomas, including our patient, most often found on the trunk and mimicking basal cell carcinoma, and three subungual acantholytic dyskeratotic acanthomas of the thumb, which mimicked onychopapilloma.

CONCLUSION

Acantholytic dyskeratotic acanthomas are clinically and pathologically distinct lesions, which may morphologically present as either truncal plaques or subungual longitudinal erythronychia.

Authors+Show Affiliations

Medical School, University of California San Diego, California, USA.Division of Dermatology, University of California San Diego, California, USA ; Dermatopathology, University of California San Diego, California, USA.Division of Dermatology, University of California San Diego, California, USA.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

25126453

Citation

Goldenberg, Alina, et al. "Acantholytic Dyskeratotic Acanthoma: Case Report and Review of the Literature." Dermatology Practical & Conceptual, vol. 4, no. 3, 2014, pp. 25-30.
Goldenberg A, Lee RA, Cohen PR. Acantholytic dyskeratotic acanthoma: case report and review of the literature. Dermatology practical & conceptual. 2014;4(3):25-30.
Goldenberg, A., Lee, R. A., & Cohen, P. R. (2014). Acantholytic dyskeratotic acanthoma: case report and review of the literature. Dermatology Practical & Conceptual, 4(3), 25-30. https://doi.org/10.5826/dpc.0403a03
Goldenberg A, Lee RA, Cohen PR. Acantholytic Dyskeratotic Acanthoma: Case Report and Review of the Literature. Dermatology practical & conceptual. 2014;4(3):25-30. PubMed PMID: 25126453.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Acantholytic dyskeratotic acanthoma: case report and review of the literature. AU - Goldenberg,Alina, AU - Lee,Robert A, AU - Cohen,Philip R, Y1 - 2014/07/31/ PY - 2014/02/15/received PY - 2014/03/19/accepted PY - 2014/8/16/entrez PY - 2014/8/16/pubmed PY - 2014/8/16/medline KW - acantholysis KW - acanthoma KW - cutaneous KW - dyskeratosis KW - nail KW - warty SP - 25 EP - 30 JF - Dermatology practical & conceptual VL - 4 IS - 3 N2 - BACKGROUND: Focal acantholytic dyskeratosis has been described as an incidental finding and as a clinically distinct lesion. In both situations, a dimorphic histologic pattern is observed: acantholysis and dyskeratosis. Solitary, non-genital lesions displaying such pathology have been difficult to classify. Clinical and pathological characteristics of acantholytic dyskeratotic acanthomas are described. METHODS: The features of a patient with solitary, non-genital, acantholytic dyskeratotic acanthoma are presented and the literature on acantholytic dyskeratotic acanthomas is reviewed. Using PubMed the following terms were searched and relevant citations assessed: acantholysis, acanthoma, cutaneous, dyskeratosis, nail, warty. RESULTS: We identified 30 cutaneous acantholytic dyskeratotic acanthomas, including our patient, most often found on the trunk and mimicking basal cell carcinoma, and three subungual acantholytic dyskeratotic acanthomas of the thumb, which mimicked onychopapilloma. CONCLUSION: Acantholytic dyskeratotic acanthomas are clinically and pathologically distinct lesions, which may morphologically present as either truncal plaques or subungual longitudinal erythronychia. SN - 2160-9381 UR - https://www.unboundmedicine.com/medline/citation/25126453/Acantholytic_dyskeratotic_acanthoma:_case_report_and_review_of_the_literature_ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25126453/ DB - PRIME DP - Unbound Medicine ER -
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