Tags

Type your tag names separated by a space and hit enter

Coffee consumption and mortality from all causes, cardiovascular disease, and cancer: a dose-response meta-analysis.
Am J Epidemiol. 2014 Oct 15; 180(8):763-75.AJ

Abstract

Several studies have analyzed the relationship between coffee consumption and mortality, but the shape of the association remains unclear. We conducted a dose-response meta-analysis of prospective studies to examine the dose-response associations between coffee consumption and mortality from all causes, cardiovascular disease (CVD), and all cancers. Pertinent studies, published between 1966 and 2013, were identified by searching PubMed and by reviewing the reference lists of the selected articles. Prospective studies in which investigators reported relative risks of mortality from all causes, CVD, and all cancers for 3 or more categories of coffee consumption were eligible. Results from individual studies were pooled using a random-effects model. Twenty-one prospective studies, with 121,915 deaths and 997,464 participants, met the inclusion criteria. There was strong evidence of nonlinear associations between coffee consumption and mortality for all causes and CVD (P for nonlinearity < 0.001). The largest risk reductions were observed for 4 cups/day for all-cause mortality (16%, 95% confidence interval: 13, 18) and 3 cups/day for CVD mortality (21%, 95% confidence interval: 16, 26). Coffee consumption was not associated with cancer mortality. Findings from this meta-analysis indicate that coffee consumption is inversely associated with all-cause and CVD mortality.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Meta-Analysis
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

25156996

Citation

Crippa, Alessio, et al. "Coffee Consumption and Mortality From All Causes, Cardiovascular Disease, and Cancer: a Dose-response Meta-analysis." American Journal of Epidemiology, vol. 180, no. 8, 2014, pp. 763-75.
Crippa A, Discacciati A, Larsson SC, et al. Coffee consumption and mortality from all causes, cardiovascular disease, and cancer: a dose-response meta-analysis. Am J Epidemiol. 2014;180(8):763-75.
Crippa, A., Discacciati, A., Larsson, S. C., Wolk, A., & Orsini, N. (2014). Coffee consumption and mortality from all causes, cardiovascular disease, and cancer: a dose-response meta-analysis. American Journal of Epidemiology, 180(8), 763-75. https://doi.org/10.1093/aje/kwu194
Crippa A, et al. Coffee Consumption and Mortality From All Causes, Cardiovascular Disease, and Cancer: a Dose-response Meta-analysis. Am J Epidemiol. 2014 Oct 15;180(8):763-75. PubMed PMID: 25156996.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Coffee consumption and mortality from all causes, cardiovascular disease, and cancer: a dose-response meta-analysis. AU - Crippa,Alessio, AU - Discacciati,Andrea, AU - Larsson,Susanna C, AU - Wolk,Alicja, AU - Orsini,Nicola, Y1 - 2014/08/24/ PY - 2014/8/27/entrez PY - 2014/8/27/pubmed PY - 2014/12/15/medline KW - all-cause mortality KW - cancer mortality KW - cardiovascular disease mortality KW - coffee KW - dose-response relationship KW - meta-analysis KW - prospective studies SP - 763 EP - 75 JF - American journal of epidemiology JO - Am J Epidemiol VL - 180 IS - 8 N2 - Several studies have analyzed the relationship between coffee consumption and mortality, but the shape of the association remains unclear. We conducted a dose-response meta-analysis of prospective studies to examine the dose-response associations between coffee consumption and mortality from all causes, cardiovascular disease (CVD), and all cancers. Pertinent studies, published between 1966 and 2013, were identified by searching PubMed and by reviewing the reference lists of the selected articles. Prospective studies in which investigators reported relative risks of mortality from all causes, CVD, and all cancers for 3 or more categories of coffee consumption were eligible. Results from individual studies were pooled using a random-effects model. Twenty-one prospective studies, with 121,915 deaths and 997,464 participants, met the inclusion criteria. There was strong evidence of nonlinear associations between coffee consumption and mortality for all causes and CVD (P for nonlinearity < 0.001). The largest risk reductions were observed for 4 cups/day for all-cause mortality (16%, 95% confidence interval: 13, 18) and 3 cups/day for CVD mortality (21%, 95% confidence interval: 16, 26). Coffee consumption was not associated with cancer mortality. Findings from this meta-analysis indicate that coffee consumption is inversely associated with all-cause and CVD mortality. SN - 1476-6256 UR - https://www.unboundmedicine.com/medline/citation/25156996/Coffee_consumption_and_mortality_from_all_causes_cardiovascular_disease_and_cancer:_a_dose_response_meta_analysis_ DB - PRIME DP - Unbound Medicine ER -