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Caring for critically ill patients with ebola virus disease. Perspectives from West Africa.
Am J Respir Crit Care Med 2014; 190(7):733-7AJ

Abstract

The largest ever Ebola virus disease outbreak is ravaging West Africa. The constellation of little public health infrastructure, low levels of health literacy, limited acute care and infection prevention and control resources, densely populated areas, and a highly transmissible and lethal viral infection have led to thousands of confirmed, probable, or suspected cases thus far. Ebola virus disease is characterized by a febrile severe illness with profound gastrointestinal manifestations and is complicated by intravascular volume depletion, shock, profound electrolyte abnormalities, and organ dysfunction. Despite no proven Ebola virus-specific medical therapies, the potential effect of supportive care is great for a condition with high baseline mortality and one usually occurring in resource-constrained settings. With more personnel, basic monitoring, and supportive treatment, many of the sickest patients with Ebola virus disease do not need to die. Ebola virus disease represents an illness ready for a paradigm shift in care delivery and outcomes, and the profession of critical care medicine can and should be instrumental in helping this happen.

Authors+Show Affiliations

1 University of Toronto, Toronto, Ontario, Canada.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

25166884

Citation

Fowler, Robert A., et al. "Caring for Critically Ill Patients With Ebola Virus Disease. Perspectives From West Africa." American Journal of Respiratory and Critical Care Medicine, vol. 190, no. 7, 2014, pp. 733-7.
Fowler RA, Fletcher T, Fischer WA, et al. Caring for critically ill patients with ebola virus disease. Perspectives from West Africa. Am J Respir Crit Care Med. 2014;190(7):733-7.
Fowler, R. A., Fletcher, T., Fischer, W. A., Lamontagne, F., Jacob, S., Brett-Major, D., ... Bausch, D. (2014). Caring for critically ill patients with ebola virus disease. Perspectives from West Africa. American Journal of Respiratory and Critical Care Medicine, 190(7), pp. 733-7. doi:10.1164/rccm.201408-1514CP.
Fowler RA, et al. Caring for Critically Ill Patients With Ebola Virus Disease. Perspectives From West Africa. Am J Respir Crit Care Med. 2014 Oct 1;190(7):733-7. PubMed PMID: 25166884.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Caring for critically ill patients with ebola virus disease. Perspectives from West Africa. AU - Fowler,Robert A, AU - Fletcher,Thomas, AU - Fischer,William A,2nd AU - Lamontagne,Francois, AU - Jacob,Shevin, AU - Brett-Major,David, AU - Lawler,James V, AU - Jacquerioz,Frederique A, AU - Houlihan,Catherine, AU - O'Dempsey,Tim, AU - Ferri,Mauricio, AU - Adachi,Takuya, AU - Lamah,Marie-Claire, AU - Bah,Elhadj Ibrahima, AU - Mayet,Thierry, AU - Schieffelin,John, AU - McLellan,Susan L, AU - Senga,Mikiko, AU - Kato,Yasuyuki, AU - Clement,Christophe, AU - Mardel,Simon, AU - Vallenas Bejar De Villar,Rosa Constanza, AU - Shindo,Nahoko, AU - Bausch,Daniel, PY - 2014/8/29/entrez PY - 2014/8/29/pubmed PY - 2015/2/28/medline KW - Africa KW - Ebola KW - critical care KW - outbreak KW - viral hemorrhagic fever SP - 733 EP - 7 JF - American journal of respiratory and critical care medicine JO - Am. J. Respir. Crit. Care Med. VL - 190 IS - 7 N2 - The largest ever Ebola virus disease outbreak is ravaging West Africa. The constellation of little public health infrastructure, low levels of health literacy, limited acute care and infection prevention and control resources, densely populated areas, and a highly transmissible and lethal viral infection have led to thousands of confirmed, probable, or suspected cases thus far. Ebola virus disease is characterized by a febrile severe illness with profound gastrointestinal manifestations and is complicated by intravascular volume depletion, shock, profound electrolyte abnormalities, and organ dysfunction. Despite no proven Ebola virus-specific medical therapies, the potential effect of supportive care is great for a condition with high baseline mortality and one usually occurring in resource-constrained settings. With more personnel, basic monitoring, and supportive treatment, many of the sickest patients with Ebola virus disease do not need to die. Ebola virus disease represents an illness ready for a paradigm shift in care delivery and outcomes, and the profession of critical care medicine can and should be instrumental in helping this happen. SN - 1535-4970 UR - https://www.unboundmedicine.com/medline/citation/25166884/full_citation L2 - http://www.atsjournals.org/doi/full/10.1164/rccm.201408-1514CP?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -