Tags

Type your tag names separated by a space and hit enter

A comparison of sedation-related events for two multiagent oral sedation regimens in pediatric dental patients.
Pediatr Dent 2014 Jul-Aug; 36(4):302-8PD

Abstract

PURPOSE

This study compared the incidence of adverse sedation-related events occurring with two different multiagent oral sedation regimens in pediatric dental patients.

METHODS

Forty healthy patients (three to six years old), received either a sedation regimen of chloral hydrate, meperidine, and hydroxyzine with nitrous oxide (CH/M/H/N2O; N=19) or a regimen of midazolam, meperidine, and hydroxyzine with nitrous oxide (MZ/M/H/N2O; N=21). The two treating dentists answered a questionnaire regarding the perioperative period. Parents received two phone interviews at eight and 24 hours after sedation. Statistical analysis included chi-square, Pearson correlation coefficient, and t-test (P<.05).

RESULTS

Children sedated with MZ/M/H/N2O showed a significant increase in hyperactivity during dental treatment, slurring/difficulty speaking, and difficulty walking postoperatively within eight hours after discharge. Children sedated with CH/M/H/N2O showed a significant increase in frequency of sleeping, talking less than normal after arriving home, and an increased need for postoperative pain medication.

CONCLUSIONS

Different oral sedation regimens produce different adverse sedation-related events. The provider of pediatric oral sedation should select a sedative regimen with an adverse sedation-related profile that he/she believes is optimal for the patient being treated. Parents should be counseled as to possible postsedation effects anticipated based on the sedative regimen administered.

Authors+Show Affiliations

Dentist in private practice, Irvine, Calif.; USA. laura@lauradds.com.Advanced Education Program in Pediatric Dentistry, Department of Pediatric Dentistry, at Loma Linda University School of Dentistry, Loma Linda, Calif.; USA.Advanced Education Program in Dental Anesthesiology, Department of Dental Anesthesiology, at Loma Linda University School of Dentistry, Loma Linda, Calif.; USA.Advanced Education Program in Pediatric Dentistry, Department of Pediatric Dentistry, at Loma Linda University School of Dentistry, Loma Linda, Calif.; USA.

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

25197995

Citation

McCormack, Laura, et al. "A Comparison of Sedation-related Events for Two Multiagent Oral Sedation Regimens in Pediatric Dental Patients." Pediatric Dentistry, vol. 36, no. 4, 2014, pp. 302-8.
McCormack L, Chen JW, Trapp L, et al. A comparison of sedation-related events for two multiagent oral sedation regimens in pediatric dental patients. Pediatr Dent. 2014;36(4):302-8.
McCormack, L., Chen, J. W., Trapp, L., & Job, A. (2014). A comparison of sedation-related events for two multiagent oral sedation regimens in pediatric dental patients. Pediatric Dentistry, 36(4), pp. 302-8.
McCormack L, et al. A Comparison of Sedation-related Events for Two Multiagent Oral Sedation Regimens in Pediatric Dental Patients. Pediatr Dent. 2014;36(4):302-8. PubMed PMID: 25197995.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A comparison of sedation-related events for two multiagent oral sedation regimens in pediatric dental patients. AU - McCormack,Laura, AU - Chen,Jung-Wei, AU - Trapp,Larry, AU - Job,Allen, PY - 2014/9/9/entrez PY - 2014/9/10/pubmed PY - 2015/7/29/medline SP - 302 EP - 8 JF - Pediatric dentistry JO - Pediatr Dent VL - 36 IS - 4 N2 - PURPOSE: This study compared the incidence of adverse sedation-related events occurring with two different multiagent oral sedation regimens in pediatric dental patients. METHODS: Forty healthy patients (three to six years old), received either a sedation regimen of chloral hydrate, meperidine, and hydroxyzine with nitrous oxide (CH/M/H/N2O; N=19) or a regimen of midazolam, meperidine, and hydroxyzine with nitrous oxide (MZ/M/H/N2O; N=21). The two treating dentists answered a questionnaire regarding the perioperative period. Parents received two phone interviews at eight and 24 hours after sedation. Statistical analysis included chi-square, Pearson correlation coefficient, and t-test (P<.05). RESULTS: Children sedated with MZ/M/H/N2O showed a significant increase in hyperactivity during dental treatment, slurring/difficulty speaking, and difficulty walking postoperatively within eight hours after discharge. Children sedated with CH/M/H/N2O showed a significant increase in frequency of sleeping, talking less than normal after arriving home, and an increased need for postoperative pain medication. CONCLUSIONS: Different oral sedation regimens produce different adverse sedation-related events. The provider of pediatric oral sedation should select a sedative regimen with an adverse sedation-related profile that he/she believes is optimal for the patient being treated. Parents should be counseled as to possible postsedation effects anticipated based on the sedative regimen administered. SN - 1942-5473 UR - https://www.unboundmedicine.com/medline/citation/25197995/A_comparison_of_sedation_related_events_for_two_multiagent_oral_sedation_regimens_in_pediatric_dental_patients_ L2 - https://www.ingentaconnect.com/openurl?genre=article&amp;issn=0164-1263&amp;volume=36&amp;issue=4&amp;spage=302&amp;aulast=McCormack DB - PRIME DP - Unbound Medicine ER -