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Increased subsequent risk of acute coronary syndrome for patients with dermatomyositis/polymyositis: a nationwide population-based retrospective cohort study.
Scand J Rheumatol. 2015; 44(1):42-7.SJ

Abstract

OBJECTIVES

The aim of this study was to explore the possible association between dermatomyositis/polymyositis (DM/PM) and subsequent acute coronary syndrome (ACS) risk.

METHOD

We used data from the National Health Insurance (NHI) system of Taiwan to address the research topic. The exposure cohort contained 2029 patients with new diagnoses of DM/PM. Each patient was randomly frequency-matched according to sex and age with four participants from the general population who did not have a history of ACS at the index date (control group). Cox proportional hazard regression analyses were conducted to estimate the relationship between DM/PM and subsequent ACS risk.

RESULTS

Among patients with DM/PM, the overall risk for developing subsequent ACS was significantly higher than that of the control group [adjusted hazard ratio (aHR) 1.98, 95% confidence interval (CI) 1.17-3.35]. Further analysis indicated a higher risk in patients who were male, older, or diagnosed with comorbidities.

CONCLUSIONS

The findings from this population-based retrospective cohort study suggest that DM/PM is associated with an increased subsequent ACS risk.

Authors+Show Affiliations

Division of Cardiology, Department of Internal Medicine, China Medical University Hospital , Taichung , Taiwan.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

25205256

Citation

Lin, Y-N, et al. "Increased Subsequent Risk of Acute Coronary Syndrome for Patients With Dermatomyositis/polymyositis: a Nationwide Population-based Retrospective Cohort Study." Scandinavian Journal of Rheumatology, vol. 44, no. 1, 2015, pp. 42-7.
Lin YN, Lin CL, Chang KC, et al. Increased subsequent risk of acute coronary syndrome for patients with dermatomyositis/polymyositis: a nationwide population-based retrospective cohort study. Scand J Rheumatol. 2015;44(1):42-7.
Lin, Y. N., Lin, C. L., Chang, K. C., & Kao, C. H. (2015). Increased subsequent risk of acute coronary syndrome for patients with dermatomyositis/polymyositis: a nationwide population-based retrospective cohort study. Scandinavian Journal of Rheumatology, 44(1), 42-7. https://doi.org/10.3109/03009742.2014.918652
Lin YN, et al. Increased Subsequent Risk of Acute Coronary Syndrome for Patients With Dermatomyositis/polymyositis: a Nationwide Population-based Retrospective Cohort Study. Scand J Rheumatol. 2015;44(1):42-7. PubMed PMID: 25205256.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Increased subsequent risk of acute coronary syndrome for patients with dermatomyositis/polymyositis: a nationwide population-based retrospective cohort study. AU - Lin,Y-N, AU - Lin,C-L, AU - Chang,K-C, AU - Kao,C-H, Y1 - 2014/09/10/ PY - 2014/9/11/entrez PY - 2014/9/11/pubmed PY - 2015/3/11/medline SP - 42 EP - 7 JF - Scandinavian journal of rheumatology JO - Scand. J. Rheumatol. VL - 44 IS - 1 N2 - OBJECTIVES: The aim of this study was to explore the possible association between dermatomyositis/polymyositis (DM/PM) and subsequent acute coronary syndrome (ACS) risk. METHOD: We used data from the National Health Insurance (NHI) system of Taiwan to address the research topic. The exposure cohort contained 2029 patients with new diagnoses of DM/PM. Each patient was randomly frequency-matched according to sex and age with four participants from the general population who did not have a history of ACS at the index date (control group). Cox proportional hazard regression analyses were conducted to estimate the relationship between DM/PM and subsequent ACS risk. RESULTS: Among patients with DM/PM, the overall risk for developing subsequent ACS was significantly higher than that of the control group [adjusted hazard ratio (aHR) 1.98, 95% confidence interval (CI) 1.17-3.35]. Further analysis indicated a higher risk in patients who were male, older, or diagnosed with comorbidities. CONCLUSIONS: The findings from this population-based retrospective cohort study suggest that DM/PM is associated with an increased subsequent ACS risk. SN - 1502-7732 UR - https://www.unboundmedicine.com/medline/citation/25205256/Increased_subsequent_risk_of_acute_coronary_syndrome_for_patients_with_dermatomyositis/polymyositis:_a_nationwide_population_based_retrospective_cohort_study_ L2 - http://www.tandfonline.com/doi/full/10.3109/03009742.2014.918652 DB - PRIME DP - Unbound Medicine ER -