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Intensive low-glycaemic-load dietary intervention for the management of glycaemia and serum lipids among women with gestational diabetes: a randomized control trial.
Public Health Nutr 2015; 18(8):1506-13PH

Abstract

OBJECTIVE

The present study aimed to compare the effects of a general dietary intervention and an intervention with low glycaemic load (GL) on glycaemic control, blood lipid metabolism and pregnancy outcomes in women with gestational diabetes mellitus.

DESIGN

Participants were randomly assigned to two groups, receiving either an individualized general dietary intervention (Control group) or an intensive low-GL intervention (Low-GL group) every two weeks, from 24-26 weeks of gestation to delivery.

SETTING

The Center of Maternal Primary Care in Guangdong General Hospital, China.

SUBJECTS

Ninety-five women with gestational diabetes mellitus were enrolled from June 2008 to July 2009.

RESULTS

After the intervention, both groups significantly decreased their dietary intakes of energy, fat and carbohydrate. The Low-GL group had significantly lower values for GL (122 v. 136) and glycaemic index (50 v. 54) but greater dietary fibre intake (33 v. 29 g/d) than did the Control group (all P<0·01). Significantly greater decreases in fasting plasma glucose (-0·33 v. -0·02 mmol/l, P<0·01) and 2 h postprandial glucose (-2·98 v. -2·51 mmol/l, P<0·01), significantly lower increases in total cholesterol (0·12 v. 0·23 mmol/l) and TAG (0·41 v. 0·56 mmol/l) and a significantly lower decrease in HDL cholesterol (-0·01 v. -0·11 mmol/l) were also observed in the Low-GL group compared with the Control group (all P<0·05). There were no significant differences in body weight gain, birth weight or other maternal-fetal perinatal outcomes between the two groups.

CONCLUSIONS

The low-GL targeted dietary intervention outperformed the general dietary intervention in glycaemic control and the improvement of blood lipid levels in women with gestational diabetes mellitus.

Authors+Show Affiliations

1Guangdong General Hospital,Guangdong Academy of Medical Science,Guangzhou,People's Republic of China.1Guangdong General Hospital,Guangdong Academy of Medical Science,Guangzhou,People's Republic of China.2Faculty of Nutrition,School of Public Health,Sun Yat-sen University,74th Zhongshan II Road,Guangzhou 510080,People's Republic of China.1Guangdong General Hospital,Guangdong Academy of Medical Science,Guangzhou,People's Republic of China.1Guangdong General Hospital,Guangdong Academy of Medical Science,Guangzhou,People's Republic of China.1Guangdong General Hospital,Guangdong Academy of Medical Science,Guangzhou,People's Republic of China.1Guangdong General Hospital,Guangdong Academy of Medical Science,Guangzhou,People's Republic of China.2Faculty of Nutrition,School of Public Health,Sun Yat-sen University,74th Zhongshan II Road,Guangzhou 510080,People's Republic of China.2Faculty of Nutrition,School of Public Health,Sun Yat-sen University,74th Zhongshan II Road,Guangzhou 510080,People's Republic of China.

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

25222105

Citation

Ma, Wen-Jun, et al. "Intensive Low-glycaemic-load Dietary Intervention for the Management of Glycaemia and Serum Lipids Among Women With Gestational Diabetes: a Randomized Control Trial." Public Health Nutrition, vol. 18, no. 8, 2015, pp. 1506-13.
Ma WJ, Huang ZH, Huang BX, et al. Intensive low-glycaemic-load dietary intervention for the management of glycaemia and serum lipids among women with gestational diabetes: a randomized control trial. Public Health Nutr. 2015;18(8):1506-13.
Ma, W. J., Huang, Z. H., Huang, B. X., Qi, B. H., Zhang, Y. J., Xiao, B. X., ... Zhu, H. L. (2015). Intensive low-glycaemic-load dietary intervention for the management of glycaemia and serum lipids among women with gestational diabetes: a randomized control trial. Public Health Nutrition, 18(8), pp. 1506-13. doi:10.1017/S1368980014001992.
Ma WJ, et al. Intensive Low-glycaemic-load Dietary Intervention for the Management of Glycaemia and Serum Lipids Among Women With Gestational Diabetes: a Randomized Control Trial. Public Health Nutr. 2015;18(8):1506-13. PubMed PMID: 25222105.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Intensive low-glycaemic-load dietary intervention for the management of glycaemia and serum lipids among women with gestational diabetes: a randomized control trial. AU - Ma,Wen-Jun, AU - Huang,Zhi-Hong, AU - Huang,Bi-Xia, AU - Qi,Ben-Hua, AU - Zhang,Yan-Jun, AU - Xiao,Ben-Xi, AU - Li,Yuan-Hong, AU - Chen,Li, AU - Zhu,Hui-Lian, Y1 - 2014/09/15/ PY - 2014/9/16/entrez PY - 2014/9/16/pubmed PY - 2016/4/26/medline KW - Gestational diabetes mellitus SP - 1506 EP - 13 JF - Public health nutrition JO - Public Health Nutr VL - 18 IS - 8 N2 - OBJECTIVE: The present study aimed to compare the effects of a general dietary intervention and an intervention with low glycaemic load (GL) on glycaemic control, blood lipid metabolism and pregnancy outcomes in women with gestational diabetes mellitus. DESIGN: Participants were randomly assigned to two groups, receiving either an individualized general dietary intervention (Control group) or an intensive low-GL intervention (Low-GL group) every two weeks, from 24-26 weeks of gestation to delivery. SETTING: The Center of Maternal Primary Care in Guangdong General Hospital, China. SUBJECTS: Ninety-five women with gestational diabetes mellitus were enrolled from June 2008 to July 2009. RESULTS: After the intervention, both groups significantly decreased their dietary intakes of energy, fat and carbohydrate. The Low-GL group had significantly lower values for GL (122 v. 136) and glycaemic index (50 v. 54) but greater dietary fibre intake (33 v. 29 g/d) than did the Control group (all P<0·01). Significantly greater decreases in fasting plasma glucose (-0·33 v. -0·02 mmol/l, P<0·01) and 2 h postprandial glucose (-2·98 v. -2·51 mmol/l, P<0·01), significantly lower increases in total cholesterol (0·12 v. 0·23 mmol/l) and TAG (0·41 v. 0·56 mmol/l) and a significantly lower decrease in HDL cholesterol (-0·01 v. -0·11 mmol/l) were also observed in the Low-GL group compared with the Control group (all P<0·05). There were no significant differences in body weight gain, birth weight or other maternal-fetal perinatal outcomes between the two groups. CONCLUSIONS: The low-GL targeted dietary intervention outperformed the general dietary intervention in glycaemic control and the improvement of blood lipid levels in women with gestational diabetes mellitus. SN - 1475-2727 UR - https://www.unboundmedicine.com/medline/citation/25222105/Intensive_low_glycaemic_load_dietary_intervention_for_the_management_of_glycaemia_and_serum_lipids_among_women_with_gestational_diabetes:_a_randomized_control_trial_ L2 - https://www.cambridge.org/core/product/identifier/S1368980014001992/type/journal_article DB - PRIME DP - Unbound Medicine ER -