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Recent advances in clinical parasitology diagnostics.
Curr Infect Dis Rep 2014; 16(11):434CI

Abstract

Microscopy has several limitations in the diagnosis of parasitic infection. New technologies have emerged to address some of these limitations. We review recent advances in three key areas. The detection of enteric protozoa is a commonly requested test, particularly with increasing travel to and migration from endemic countries. Microscopy is slow and labor intensive and requires a high level of technical expertise. It also lacks both sensitivity and specificity. Recently developed nucleic acid amplification tests are automated and rapid and show superior accuracy. Proteomics shows promise for both the diagnosis of infections where parasite detection is difficult and the potential for accurate assessment of cure in these cases. Finally, rapid and simple diagnostic tests suitable for use in low-resource settings are now allowing for improved study and control of infection in endemic regions.

Authors+Show Affiliations

J.D. MacLean Centre for Tropical Diseases, McGill University Health Centre, 1650 Cedar Avenue, Room L10.509, Montreal, H3G 1A4, Canada.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

25230603

Citation

Yansouni, Cedric P., et al. "Recent Advances in Clinical Parasitology Diagnostics." Current Infectious Disease Reports, vol. 16, no. 11, 2014, p. 434.
Yansouni CP, Merckx J, Libman MD, et al. Recent advances in clinical parasitology diagnostics. Curr Infect Dis Rep. 2014;16(11):434.
Yansouni, C. P., Merckx, J., Libman, M. D., & Ndao, M. (2014). Recent advances in clinical parasitology diagnostics. Current Infectious Disease Reports, 16(11), p. 434. doi:10.1007/s11908-014-0434-9.
Yansouni CP, et al. Recent Advances in Clinical Parasitology Diagnostics. Curr Infect Dis Rep. 2014;16(11):434. PubMed PMID: 25230603.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Recent advances in clinical parasitology diagnostics. AU - Yansouni,Cedric P, AU - Merckx,Joanna, AU - Libman,Michael D, AU - Ndao,Momar, PY - 2014/9/19/entrez PY - 2014/9/19/pubmed PY - 2014/9/19/medline SP - 434 EP - 434 JF - Current infectious disease reports JO - Curr Infect Dis Rep VL - 16 IS - 11 N2 - Microscopy has several limitations in the diagnosis of parasitic infection. New technologies have emerged to address some of these limitations. We review recent advances in three key areas. The detection of enteric protozoa is a commonly requested test, particularly with increasing travel to and migration from endemic countries. Microscopy is slow and labor intensive and requires a high level of technical expertise. It also lacks both sensitivity and specificity. Recently developed nucleic acid amplification tests are automated and rapid and show superior accuracy. Proteomics shows promise for both the diagnosis of infections where parasite detection is difficult and the potential for accurate assessment of cure in these cases. Finally, rapid and simple diagnostic tests suitable for use in low-resource settings are now allowing for improved study and control of infection in endemic regions. SN - 1523-3847 UR - https://www.unboundmedicine.com/medline/citation/25230603/full_citation L2 - https://dx.doi.org/10.1007/s11908-014-0434-9 DB - PRIME DP - Unbound Medicine ER -